Buy Tizanidine Online In The USA To Treat Muscle Pain

Tizanidine (Zanaflex) is a short-acting muscle relaxer. It has been shown to be more effective than other antispasmodic drugs and is more tolerable than baclofen and Flexeril.
The drug was approved for medical use in the United States in 1996. In the year 2018, it ranked 86th as the most commonly prescribed medication in the U.S., with over 8 million prescriptions.

Tizanidine treats muscle spasticity and spinal cord injury by temporarily relaxing muscle tone. To know more, read the blog thoroughly.

A Brief On Zanaflex

Tizanidine is sold under the brand name Zanaflex, Sirdalud, and others. Tizanidine (Zanaflex) is a class of muscle relaxers called an alpha-2 adrenergic receptor agonist. Zanaflex is used to treat muscle spasms caused by conditions such as spinal cord injury or multiple sclerosis. It belongs to a category of drugs called alpha-2 adrenergic agonists, which work by blocking certain nerve signals in the brain and spinal cord that cause muscles to tighten.

How Does Zanaflex Work?

Tizanidine (Zanaflex) works by selectively stimulating alpha-2 adrenergic receptors in the central nervous system. When these receptors are stimulated, it inhibits the release of neurotransmitters such as norepinephrine that initiate and maintain muscle spasticity.

This reduction in neurotransmitter release leads to a decrease in the activity of motor neurons in the brain and spinal cord that regulate muscle contractions. This decrease in activity, in turn, reduces muscle tone and overall muscle spasticity. This is why Zanaflex is used to treat conditions such as spinal cord injury and multiple sclerosis, which can cause muscle spasticity.

In simple words, Zanaflex affects the connection of pain sensitization between the brain and the spinal cord, which helps to relax the muscle.

Usages Of Zanaflex

As mentioned above, Tizanidine (Zanaflex) is a muscle relaxant. It is used to treat muscle spasms caused by spinal cord injury, multiple sclerosis, or other conditions that affect muscle. Zanaflex is typically prescribed to treat Spasticity. Which is the condition where muscles become stiff and difficult to control.

Various conditions, such as multiple sclerosis, spinal cord injuries, and cerebral palsy can cause it.  Zanaflex also treats muscle spasms that are caused by conditions such as Fibromyalgia or tizanidine for backpain is helpful.

Tizanidine for headaches is useful, especially those caused by muscle tension. It may help reduce headaches’ frequency and severity by relaxing muscles and reducing spasms.

It’s important to note that off-label use of Tizanidine (Zanaflex) without your doctor’s advice may cause severe side effects.

Is Zanaflex Considered As Narcotic?

Tizanidine (Zanaflex) is a narcotic substance. Such type of questions always pops up however it can make people dependent i.e tizanidine addictive in nature. The misconception starts from the abuse rate and the prescription compulsion thing. Many folks abuse muscle relaxers making it into a controlled substance. Declaring Narcotic substance has many other legal things as well as attributes involved hence Zanaflex doesn’t come under Narcotic substance.

Dosages, Forms And Strength Of Zanaflex




2mg, 4mg, 6mg


2mg, 4mg



Adult: The typical starting dose is 2mg by mouth thrice daily. The dose can be raised slowly if needed up to a total of 36 mg in a day

Children: Use and dose according to the prescription by a doctor

Precautions for Tizanidine (Zanaflex):

Tizanidine (Zanaflex) is a prescription medication that should only be taken with the proper precaution.

Here are some precautions for Tizanidine (Zanaflex):

  • Inform your doctor about your medical history and the medicine you are currently taking before using Zanaflex. Tizanidine may interact with certain medications and medical conditions.
  • Follow the dosage and usage according to the prescription given by your doctor. Do not increase the dosage or duration. It may cause serious side effects.
  • Avoid driving or operating heavy machinery, which needs alertness.
  • Do not suddenly halt the Zanaflex after using it for a prolonged period. It may cause withdrawal symptoms.
  • Zanaflex may cause liver damage. Especially the person with a history of liver disease may have a higher risk of side effects. Your doctor may monitor your liver function while you are taking Zanaflex.
  • Inform your doctor if you have a blood pressure and heart disease history. As zanaflex can cause low blood pressure and slow down your heart rate.
  • Zanaflex may cause a dry mouth. So it’s important to keep your mouth hygienic to prevent yourself from having a dry mouth.
  • Pregnant and breastfeeding women should consult a doctor before using Zanaflex, as this medication may be passed into breast milk and may harm the baby.
  • Use Tizanidine (Tizanidine) according to the prescription and follow the precaution properly to avoid the Flexeril side effects.

Side Effects Of Zanaflex Table

Tizanidine (Zanaflex) can cause a range of side effects which can vary from person to person; here are the table of common side effects and serious side effects of Zanaflex

Common side effects 

Serious side effects

  • Abdominal pain
  • Constipation
  • Drowsiness
  • Dizziness
  • Dry mouth
  • Diarrhea
  • Fatigue
  • Nausea
  • Weakness
  • Flu-like symptoms, such as fever, chills, and body aches.
  • Allergic reaction
  • Liver damage
  • Low blood pressure
  • Heart problem
  • Mental health issue
  • Severe skin reaction
  • Muscle weakness
  • Respiratory depression

Interactions Of Zanaflex

Tizanidine (Zanaflex) may interact with other medications or substances. Which can affect the effectiveness of the medication and may cause serious health issues;

Here are some examples of the potential interaction;

  • Other muscle relaxants or sedative substances: taking Zanaflex with other medications which have sedative effects, such as benzodiazepines and alcohol, can increase the risk of drowsiness, dizziness, and difficulty breathing.
  • Blood pressure medication: Zanaflex may lower your medication, so taking another low pressure medication, such as beta-blockers, can increase the risk of hypertension.
  • Antibiotics: certain antibiotics, such as ciprofloxacin and fluvoxamine, can enhance the level of Zanaflex in the body, which may raise the risk of side effects.
  • Antidepressants: some antidepressants, such as Fluvoxamine, can increase the risk of side effects such as blurred vision, constipation, dry mouth, and urinary retention.
  • Herbal supplements: some herbal supplements, such as kava, can enhance the sedative effects of Zanaflex and increase the risk of side effects.
  • It’s important to inform your doctor about all medications and supplements you are taking before starting Tizanidine (Zanaflex) to avoid potential interactions.

Can You Buy Zanaflex Online?

You can buy Tizanidine (Zanaflex) online, but it is important to do so only from a legitimate and licensed online pharmacy. Buying medication online can be risky, as some websites may sell counterfeit or expired drugs that can harm your health.

  • To ensure you purchase Zanaflex from a reputable online pharmacy, look for the following:
  • Purchase from an FDA-approved medicines pharmacy.
  • Check whether the physical address and phone number listed on the website are genuine.
  • A licensed pharmacist is available to answer any questions you may have.
  • A prescription requirement for the medication. If they don’t ask for a prescription, it may be an illegal pharmacy, or they may sell a fake product.
  • To avoid the risk of fake products, buy Zanaflex offline by showing the proper prescription.

Can You Buy Zanaflex Over The Counter?

No, Tizanidine (Zanaflex) is a prescription medication unavailable over the counter. You need a proper prescription from a licensed healthcare provider to purchase Zanaflex.


As mentioned above, Zanaflex is a prescription muscle relaxant medication. It is used to treat muscle spasms caused by multiple sclerosis, spinal cord injury, or other muscle conditions. Do not increase the dose or duration of the treatment. Use it according to the prescription and guidelines given by your doctor. Many times comparing medications can be done in order to arrive at the final decision, for eg: Zanaflex vs soma. This type of comparison can help.