Flexeril(Cyclobenzaprine) vs Soma(Carisoprodol) | The Most Trending Muscle Relaxer

Flexeril vs Soma

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Flexeril and Soma being the most trending muscle relaxer. Both have great demand. They slightly differ from each other but have similar attributes too. 

Your doctor may suggest that you try over-the-counter painkillers such as paracetamol (Tylenol) or Gabapentin and ibuprofen to relieve your pain. Your first line of treatment should be these over-the-counter drugs: non-steroidal anti-inflammatories (NSAIDs) such as ibuprofen (Advil, Naproxen, Aleve, etc.). Certain analgesics such as Tylensol (paracetamol) and Advil (ibuprofen) are also available as OTC. Muscle relaxants such as Flexeril work best for acute pain, but if you have trouble sleeping, a muscle relaxant can help when you need to rest. Like most prescription drugs, muscle relaxants and muscle relaxants are often used to treat people with back injuries or diseases that cause debilitating physical pain. 

If you have problems, your doctor may prescribe another muscle relaxant. Robaxin and Soma are two brand names of prescription drugs indicated for the treatment of muscle spasms. Both drugs are approved in the United States by the Food and Drug Administration (FDA).

What is Flexeril?

Cyclobenzaprine, sold under the brand name Flexeril, is a drug used for muscle spasms from the musculoskeletal state of sudden start. Cyclobenzaprine is available as prescription medicine in tablet form in doses up to 10 mg. It was approved in 1977 by the FDA under the brand name Flexeril. Unlike Carisoprodol, it has no addictive or uncontrolled status. You can buy Flexeril online from the certified online pharmacy taking a doctor’s prescription before consuming any medications 

What is Soma?

Soma is a muscle relaxer that helps to blocks the pain stir between the nerves and the brain. It is used together with rest and physical remedies to cure skeletal muscle states such as pain or injury.

According to Consumer Report 2, experts advise against Soma (generic name carisoprodol) because it carries a high risk of abuse and addiction, is ineffective, and the FDA has not approved skeletal muscle relaxants for long-term use, said Charles E. Argoff, MD, professor of neurology at Albany Medical College and director of the comprehensive pain program at Albany Medical Center. Soma, in particular, is a bad choice because of its potential for abuse and addiction. 

Is Flexeril and Soma the same thing?

Flexeril and Soma are both muscle relaxants. They both are associated with acute painful muscle and skeleton conditions. Both the medication may interact with alcohol and other drugs that may make one drowsy.

Flexeril comes in pill as well as liquid form, but Soma comes in only the pill form. Apart from this, they both have different side effects and which makes them different from each other.

Flexeril and Soma are both muscle relaxants. They both are associated with acute painful muscle and skeleton conditions. Both the medication may interact with alcohol and others drugs that may make one drowsy. Flexeril comes in pill as well as liquid form, but Soma comes in only the pill form. Apart from this, they both have different side effects and which makes them different from each other.

What are the side effects of Flexeril and Soma?

Side effects that occur in both the medications- 

  • Drowsiness
  • Headaches
  • Dizziness
  • Nervousness

Side effects of Flexeril include- 

  • Dry mouth
  • Fatigue
  • Nausea
  • Constipation
  • Blurred vision
  • Awful taste
  • Confusion
  • Acid reflux
  • Stomach pain 
  • Discomfort. 

Side effects of Soma include-

  • Agitation
  • Insomnia
  • Tremor
  • Irritability
  • Fainting
  • Depression
  • Abnormal heartbeat
  • Seizures


Drug interactions of Flexeril and Soma

Looking to purchase Soma at a discounted price?

Warnings and precautions of Flexeril and Soma

For Flereril-

  • SEROTONIN SYNDROME- if one is taking other medications, then it can affect the levels of serotonin in the brain. It is the chemical that is responsible for your mood; it is a rare syndrome but a dangerous one as it can threaten your life too. 
  • If you are over 65 years old, then it will cause drowsiness, and remember not to consume alcohol while medicating with Flexeril. 
  • It will cause you trouble urinating and get your eyes and mouth dry. 
  • It has been observed that people taking Flexeril will have liver problems. 

For Soma- 

  • It can cause sedation.
  • There are reports of accidents associated with the use of Soma. 
  • Overuse of Soma can lead to death.
  • It may cause problems like depression, hypotension, seizures, and other disorders.
  • Reported withdrawal symptoms like insomnia, vomiting, abdominal cramps, headache, tremors, muscle twitching, ataxia, hallucinations, and psychosis.

What is the Dosage of Cyclobenzaprine vs Carisoprodol?

 A socio-demographic analysis of the data demonstrated that users had a median age of 42.3 years (95% CI 38.1-47.8) and were between 16 and over 60 years old. The results of this study provide data on the use of muscle relaxants, but it is important to remember that the study presented information from 1988 to 1994. Antispastic drugs (Baclofen, Lioresal, Dantrolene, and Dantrium) are not normally prescribed for musculoskeletal disorders, and there is little evidence of their use. These results relate to active substances recommended for short-term use in this study and not to chronic management. 



The dose recommended for Cyclobenzaprine is 5 or 10 mg 3 times a day using immediate-release tablets. One can also take 15 or 30 mg once a day using extended-release tablets. 


For Carisoprodol recommended dose is 250 to 350 mg which is three times daily and at bedtime. The duration recommended

Is it safe to use Flexeril and Soma while being pregnant or breastfeeding?

For Flexeril: 

  • There is no such enough study of Flexeril in pregnant women. Although, when studied on animals, no important effects were observed in the fetus. So, it can be used in pregnancy only if the doctors think it is needed. 
  • During breastfeeding, should be cautious with this medication. 

For Soma: 

  • Like Flexeril, there are not enough studies present in pregnant women. 
  • Soma accumulates in breast milk in concentrations twice those in the mother’s blood. The effects of Carisoprodol on the babies of lactating mothers are undetermined. Hence it is recommended that women who are breastfeeding should be aware when using Soma.

Flexeril, Cyclobenzaprine (Soma), and Carisoprodol are muscle relaxants indicated as a supplement to rest and physical therapy to relieve muscle spasms in acute and/or painful muscle diseases. There are also two muscle relaxants called Zanaflex and Flexeril, which are used to treat fibromyalgia.


Flexeril is widely used to cure muscle spasms and is available as a generic, but it shouldn’t be used for the long term. Ease your muscles. Soma is used for muscle spasms and muscle pain, but it’s not considered a first-line treatment and is not meant for long-term therapy.

Both Soma and flexile differ from one other in some places. It varies from person to person. Users rate Carisopsrodol higher, so the evaluation of Skelaxin vs. Soma might be worthwhile for those looking for an alternative.

Soma and Zanaflex both are almost similar. Flexeril vs Soma is a medicine used as a muscle relaxant and approved for the short-term treatment of various painful musculoskeletal disorders.

Two muscle relaxants, Zanaflex and Flexeril, have not been approved for the treatment of fibromyalgia by the Food and Drug Administration (FDA) but are often prescribed as off-label medicines.

No, it will not show up on the standard testing panel unless one goes for the specific testing. But it may be detectable in urine from 5-13 days after the consumption of Flexeril. 


Guay DR, Are there alternatives to the use of quinine to treat nocturnal leg cramps?, https://www.ncbi.nlm.nih.gov/pubmed/18454580 Accessed on 12/07/2021

SHARON SEE, REGINA GINZBURG, Choosing a Skeletal Muscle Relaxant, https://www.aafp.org/afp/2008/0801/p365.html  Accessed on 12/07/2021