Can you take Gabapentin and Ibuprofen together?

Gabapentin and Ibuprofen together
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Gabapentin And Ibuprofen Drug Interaction: An Overview

Gabapentin is a drug that helps in relaxing individuals suffering from seizures and epilepsy. It belongs to the anticonvulsants class of drugs. That is not its only use. It is also used to treat pain.

Individuals often complain about nerve pain caused due to tissue injury and inflammation. In fact, many adults are suffering from severe neuropathic pain at the spinal and central levels. To manage such painful sensations, doctors consider Gabapentin as the first-line drug

It reduces pain from diabetes, neuropathy, post-operative surgery, and other central nervous system disorders. But, mainly, it’s effective in treating seizures due to its anticonvulsant properties

Ibuprofen, on the other hand, is a Nonsteroidal Anti-Inflammatory Drug (NSAIDs). Ibuprofen is a potent pain-killer used for various muscular aches, including lower back pain, menstrual pain, dental pain, and inflammation caused by arthritis. You can find Ibuprofen at your nearby pharmacists or over-the-counter store. The brand name for Ibuprofen is known as Advil.

Your healthcare professional may use Gabapentin with Ibuprofen to achieve faster health results and commonly available prescriptions. Although, it is clinically proven to take Gabapentin with other chemical composites when prescribed by your doctor. However, safety is limited to a few medications, including supplements, OTC pills, and prescription medicines, which can have varied health effects.

Therefore, before taking Gabapentin, it’s significant to inform your doctor if you’re on any prescription or health supplements. Further will discuss its specific combination with Ibuprofen whether taking them together is effective or not?

Is it safe to take Gabapentin and Ibuprofen together?

Yes, you can take Gabapentin and Ibuprofen together. 

Ibuprofen is a potent pain-killer used for various muscular aches, including lower back pain, menstrual pain, dental pain, and inflammation caused by arthritis. You can find ibuprofen at your nearby pharmacists or over-the-counter store.

A few studies have indicated that taking gabapentin with an OTC drug is relatively safer. The health practitioners prescribe pain-killer like ibuprofen to suppress pain emitting from allergy or nerves.

However, it is crucial to tell your doctor about a specific brand you’re planning to intake. For example, one of the popular combinations of gabapentin and OTC medicine is Advil, made from its generic brand ibuprofen.

Interaction between Ibuprofen and Gabapentin

Although taking ibuprofen and gabapentin together is safer, it doesn’t mean that they don’t interact. Some of the common signs that can show you that this drug has started to react after their exchanging mechanism are as follows:

  • Drowsiness
  • Lack of concentration
  • Alertness
  • Confusion
  • Less attention

 Distraction are some of the common side effects of using ibuprofen and gabapentin simultaneously. This effect changes as per the biological factor.

For instance, when older adults take them together, they may suffer from a lack of motor coordination, thinking impairment, and judgment. Therefore, doctors always recommend that patients should stay away from activities requiring lots of attention and alertness, like driving a vehicle and operating a heavy piece of machinery.

Another critical factor is to obey the doctor’s written prescription. Do not stop using the medications halfway without asking for your doctor’s approval. You can buy Ibuprofen online or over the counter gabapentin from a certified online or nearest pharmacy.

Gabapentin and Ibuprofen available at a discounted rate​

The effects of Gabapentin and Ibuprofen when taken together

Both gabapentin and ibuprofen have their own medicinal properties, making them unique and best-selling in their respective drug class. However, when you combine them together, will it show the similar potential in treating is the point of concern.

To understand their effectiveness, a group of practitioners conducted a short survey. Then, they measured the potential benefits against the side effects, which gave them a positive outcome. As a result, they understood that the group of people who took gabapentin and ibuprofen in combination got positive results.

And yes, the result was medically concrete. Both, Gabapentin and Ibuprofen facilitate quick response in eliminating nerve pain, seizures, and pain after a post-operative surgery. Together these agents interact in an enhancing manner when used ethically.

Ultimately, doctors have shown a green signal to the pharmacists in rendering this medication to patients who want faster recovery. But the prescription is necessary. So it’s good to take an authorized approval before putting anything in your system. 

However, it is not compulsive that every other person can get benefitted from them. In addition, there are various other reasons, such as biological factors, current medical conditions, and past medical history, which can influence overall health.

This information is shared based on the medical research available online. We’re not recommending or stating these medications as a substitute under any circumstances. Therefore, please consult your doctor before taking them in combination.

What drugs can you take with Gabapentin?

If you’re already on a medication course or are planning to take gabapentin with other medications, please discuss it with your doctor. Inform them about any allergy or specific substance that your body is allergic to, protecting you from further setback.

Let us see few medications that you can take with gabapentin.


It’s appropriate to take pain-killers that are not composed of controlled substances as they’re less sedative in nature. Also, they do not directly react to the central nervous system, making it more potent for individuals from different age groups.

If your doctor approves, then you can anyone amongst the two of the popular pain-killers like paracetamol and aspirin together with gabapentin.

Antacid medications

They are nothing but indigestive pills consumed by individuals when suffering from acidity or other gastrointestinal effects.

Antacid medicines are composed of magnesium or aluminum that may pause or delay the absorption of gabapentin from the gut; therefore, it is advisable to maintain a short interval between the two of them.

Birth control pills

To restrict oneself from conceiving, most women often rely on contraceptive pills. They’re birth control pills that can be taken directly by mouth.

There is no harm in combining gabapentin with contraceptive pills as they don’t adversely affect them.

Strong pain-killers

Opioids like morphine is a robust pain-killer that intensifies and influences the effects of gabapentin more than its generic capacity, which results in a person feeling drowsier and tired.

So, if you’re taking them together, minimize the dose consumption to strike a balance in your mental alertness.


Prima facie Gabapentin and Ibuprofen interaction is minimal. You can safely take these two drugs together. The one aspect that you need to keep in mind is that this combination can reduce your alertness.

Otherwise, Gabapentin and Ibuprofen together is useful to treat pain after surgery, seizures, and other neuropathic pain. However, even then, it has to be taken wisely without exceeding the dose duration. Your health, age and weight needs to be analysed for the right dosage.

Also, if you happen to notice extreme changes in your body behaviour in terms of tiredness, lack of concentration, or other intolerable signs, please seek professional help to prevent further worsening.


Gabapentin/ibuprofen. Reactions Weekly1748, 217 (2019). Accessed on 21/06/2021 Accessed on 21/06/2021  Accessed on 21/06/2021

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