Strength and Dosage for Zanaflex
Strength and Dosage for Flexeril
Side Effects for Zanaflex
- dry mouth
- muscle weakness
- back pain
- increased muscle tone or spasms
- numbness or tingling
- stomach pain
Side Effects for Flexeril
- Unpleasant taste
- Acid reflux
- Abdominal pain or discomfort
- Dry mouth
- Blurred vision
Drug Interactions for Zanaflex
- Zanaflex is mostly metabolized in the liver by the CYP1A2 enzyme. Zanaflex levels in the body can be increased by drugs that block or inhibit this enzyme.
- Increased medication levels might cause sleepiness and dizziness, among other side effects.
- CYP1A2 inhibitors like ciprofloxacin and cimetidine and birth control pills containing Ethinyl estradiol should be avoided when taking Zanaflex.
- Zanaflex may interact with drugs that depress the central nervous system. Barbiturates, opioids, and benzodiazepines are examples of these medications.
- Zanaflex might intensify their effects, causing dizziness and sedation.
Study on the effectiveness of Zanaflex and FlexerilCyclobenzaprine has been evaluated in most clinical trials with evidence to support its usage, according to a meta-analysis. Tizanidine has been shown to help with spasticity caused by multiple sclerosis. For musculoskeletal problems, such as acute neck or back pain, both cyclobenzaprine and tizanidine were proven to be helpful. Over 100 trials comparing muscle relaxants such as Lioresal (baclofen), Soma (carisoprodol), Robaxin (methocarbamol), Skelaxin (metaxalone), and Valium were included in the meta-analysis (diazepam). Overall, the study discovered that the efficacy and safety of these medications are equal. Muscle relaxants, according to certain guidelines, produce drowsiness and should only be used for a short period. Both Zanaflex and Flexeril are efficient muscular spasm and pain relievers. On a case-by-case basis, they are used depending on which one is most appropriate. There is currently no clinical evidence that shows a direct comparison between these two medicines (Chou R, Peterson K, Helfand M)
Is there a difference between Zanaflex and Flexeril?
Flexeril and Zanaflex are not the same things. Flexeril has an average half-life of 18 hours, while Zanaflex has a half-life of roughly 2.5 hours. Flexeril is only available in extended-release capsules, whilst Zanaflex is only available in immediate-release oral tablets and capsules(Peterson, K. and Helfand, M., 2004).
Is it better to take Zanaflex or Flexeril?
Zanaflex is a relatively new medicine that has been licensed by the FDA to treat muscle spasticity caused by multiple sclerosis and spinal cord injury. Flexeril is an older medication that has been examined extensively for musculoskeletal pain and spasms. The better medicine is the one that is most effective for your condition. Consult a doctor for assistance in determining the best course of action for you(Dickerson, L.M., 2010).