Tylenol vs Ibuprofen

Tylenol vs Ibuprofen

Table of Contents

What Is Tylenol?

Tylenol is a drug used for various pains in the body as the Medication involves different cures for other body pains and fever. It is a class of Analgesics.

The generic name for Tylenol is acetaminophen. It is one of the pain relievers seen in today’s world—this Medication, primarily known in the USA.

You can also buy Tylenol over the counter from registered pharmacy.

What Is Ibuprofen?

Ibuprofen is an anti-inflammatory drug (NSAIDs) that belongs to the class of nonsteroidal.

It reduces different hormones that cause pain and inflammation in the body. It helps in curing various aches and pains in the body.

It is also an OTC medication, you can also buy Ibuprofen from certified pharmacy.

How Does Tylenol Work?

Tylenol is an analgesic and even antipyretic. Tylenol works by obstructing the brain from emitting bodily substances which take out pains in the body. It cures the mild pains in the body. This works as a tool to obstruct pains, aches in the body. (Waldstein, A., 2006)

How Does Ibuprofen Work?

Ibuprofen works by obstructing the production of cyclooxygenase from the body. It helps in reducing pains, swelling, and inflammation. It has a more significant response to injuries and illness. (Xaudiera, S. and Cardenal, A.S., 2020)

Forms And Strengths Of Tylenol



1- Tablet form

325mg, 500mg, 625mg

2- Liquid gel


Forms And Strengths Of Ibuprofen.



1- Tablet

100mg, 200mg, 400mg, 600mg, 800mg

2- Liquid

100mg per 5ml, 50mg per 1.5ml  (infants)

3- Capsule


4- Chewable tablet


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How Should You Take Tylenol?

A person should consume Tylenol as per the instructions printed on the label or the doctor’s suggestion. Tylenol can be consumed after and before food intake with enough water intake before having it.

How Should You Take Ibuprofen?

Ibuprofen is a medicine that should be taken after food intake.

Always follow the instructions given on the label and the doctor’s recommendation.

Syrup form– You should shake the bottle for 10 seconds.

Tablet form– It should be swallowed with water as prescribed by the doctor.

Dosage Of Tylenol


The person can consume two tablets of 500mg in 4 to 6 hours in one dose (If required)

Single-dose can be more than 1000mg

The maximum dose for a day can be taken of 4000mg

A person should consult a doctor before consuming it (Only ten days advisable)


Dosage of Tylenol 325-650mg can be consumed in 1 dose every 4-6 hours

It should not exceed more than five doses a day (3250mg)

Different people can be given extra doses according to their weight and age.

Dosage Of Ibuprofen


A person can consume 800 mg per dose, extending to 3200mg per day.

(Overall 4 doses per day is recommendable)


Children’s doses differ in their age and weight.

For the exact dose, they should consult a doctor.

Who Should Not Take Tylenol?

  • The person who intakes alcohol three times a day
  • If the person has severe liver issues
  • If the person is pregnant (advisable after doctors recommendation)
  • If the person gives breastfeeding to a child, it’s not recommendable because it gets mixed into the milk, which can be harmful.
  • If the person is younger than two years.
  • Undernutrition person
  • Kidney failure
  • Allergic to acetaminophen.

Who Should Not Take Ibuprofen?

Ibuprofen should not be taken by following conditions:

  • A person suffering from allergic issues
  • Who gets asthma attacks
  • Pregnant ladies (unless recommended by a doctor)
  • Children younger than six years old
  • If the person has skin reactions
  • Running nose

Side Effects Of Tylenol

There are no side effects that affect it but contact the doctor if you feel this. If you have unusual effects on your body:

  • Allergic Reaction on the body
  • Rashes on the body
  • Itching
  • Swelling of the tongue, face, throats
  • Sleepy
  • A problem in breathing normally
  • Urine (Dark)
  • Skin becoming yellow.
  • Severe Effects may include
  • Bleeding in intestine
  • Kidney damage
  • Reduce blood count
  • Constipation

Side Effects Of Ibuprofen

Ibuprofen side effects on the body

  • Stomach ache
  • Gastric issues
  • Constipation
  • Heartburn
  • Weight gain
  • Swelling, rashes
  • Liver problem
  • Kidney issues
  • Reducing blood cells
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Drug Interaction With Tylenol

  • Similar drugs are related to acetaminophen.
  • Anesthetics
  • Antibiotics
  • Nicotine
  • Alcohol
  • Anticonvulsants
  • Other fever-related medicines.

Before consuming this drug, Inform the doctor to understand the cause better.

Drug Interaction With Ibuprofen

These are the everyday drug interactions that can be seen

  • Cyclosporine
  • Lithium
  • Methotrexate
  • Blood thinner
  • Blood pressure including water pill
  • Steroids medicine


A study was conducted by S A Cooper et al. to observe the relief of pains in the body.


To observe the random trial between Ibuprofen and acetaminophen (Tylenol) on the Reaction to the pain.


This study was conducted for 6 hours, including 184 members in the panel. Those 184 members were patients who had undergone dental surgery. This study included Ibuprofen 400mg and Tylenol 1000mg.; it was studied to know which Medication would be useful for the pain to get cured in the safest way possible. They observed at regular intervals of 6 hours.


184 were the people with the exact dosage given (given as above). The results surprised the researchers with having Ibuprofen being the most curable one compared to Tylenol. There were side effects on a few patients, but more effective with the Ibuprofen drug. Ibuprofen was safer in comparison with Tylenol in terms of pain.


Both medications have their ways of treating different issues (pains). According to the study, Ibuprofen is a medication that acts more useful for people compared to Tylenol.