Tylenol (Acetaminophen)


Tylenol, the brand name for Acetaminophen, belongs to two classes of medications called analgesics (pain relievers) and antipyretics (fever reducers). It is widely used to treat mild to moderate pain and moderate to severe pain or reduce fever in conjunction with opiates. Its mechanism of action is to change the way the body senses and responds to pain and cool the body. Acetaminophen treats several common conditions, including migraine, muscle aches, menstrual cramps, backache, toothaches, sore throat, colds, fevers, flu, and arthritis (Sholal, J.B. and Smilkstein, M.J., 1996).

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Forms and strengths of Tylenol

Tylenol adult acetaminophen medications come in three strengths:
• Regular strength (325 mg)
• Extra strength (500 mg)
• Extended-release Tylenol 8 HR (625 mg).

There are two types of Tylenol Regular Strength: Tablets(325mg) and liquid gel capsules (325mg)

Dosage for Tylenol

  • The usual dose of immediate-release formulations for adults is 325mg to 650 mg every 4 hours or 500mg every 8 hours.
  • The dose for extended-release capsules is 1300mg every 8 hours. The maximum daily dose must not exceed 4 grams.
  • The oral dose for children is based on the individual child’s age and weight. If the child is younger than 12 years, the dosing is 10mg to 15mg/kg every 6 to 8 hours. The maximum daily dose is 2.6g/day (5 doses a day).
  • If the child is older than 12 years, the dose is 40mg to 60mg/kg/day every 6 hours. The maximum daily dose is 3ch.75 g/day (5 doses).
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What are the Possible Side effects of Tylenol?

The most common side effects caused by Tylenol include:

  • Headache,
  • Nausea,
  • Stomach pain,
  • Loss of appetite,
  • Itching,
  • Rash,
  • Yellowing of skin or eyes (jaundice)
  • Dark urine,
  • Clay-colored stools, and Constipation

Tylenol may cause serious side effects, including:

  • Severe rash or itching and swelling (especially of the face, tongue, or throat),
  • Severe dizziness,
  • Trouble breathing

Get immediate medical attention if you experience any of the symptoms mentioned above.

Inform your doctor if you have any side effects that are persistent or severe.

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Warnings and Precautions

  • You should not consume Tylenol if you are allergic to it.
  • An overdose of Acetaminophen can potentially damage your liver or, in extreme cases, may even cause death.
  • Adults or teenagers who weigh at least 50kgs (110 pounds) should not consume more than 1000mg in a single dose or more than 4000mg in 24 hours.
  • Children younger than 12 years must not consume more than five doses in 24 hours. Use exactly as advised by the child’s healthcare provider or exactly as directed on the label.
  • Without the advice of a doctor, do not give this medicine to a child younger than two years old.
  • Do not consume other medications that contain Acetaminophen (sometimes abbreviated as APAP), as that might result in a fatal overdose.
  • Get in touch with your doctor immediately if you have itching, loss of appetite, nausea, pain in your upper stomach, dark urine, clay-colored stools, or jaundice.
  • Stop using Tylenol and call your healthcare provider at once if you have skin redness or a rash that is spreading or causing blistering or peeling.
  • Do not consume Acetaminophen without medical advice if you have ever suffered from cirrhosis (alcoholic liver disease) or if you consume over three alcoholic beverages a day.
  • Your healthcare provider will determine whether acetaminophen is safe for you to consume during pregnancy. Do not use this medicine without the advice of your doctor if you are pregnant. Or during lactation, as it can pass into breast milk and potentially harm a nursing baby. (Parker, R.M., 2012)

Drug Interactions

  • Acetaminophen is found in a number of cold, flu, sinus, and arthritis treatments. Taking one or more of these medications increases the risk of acetaminophen intoxication or overdose.

    Other drugs may reduce the effectiveness of acetaminophen or increase the risk of acetaminophen-induced liver damage. Alcohol, anaesthetics, barbiturates, nicotine, some antibiotics, and certain anticonvulsants are among these drugs. Other possible medication interactions with Tylenol should be discussed with a healthcare provider.

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In the Event of an Overdose

An acetaminophen overdose can be lethal. Seek medical help as soon as possible. Loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness are the initial indicators of an acetaminophen overdose. Pain in the upper stomach, black urine, and yellowing of the skin or the whites of your eyes are some of the later signs.