tylenol on empty stomach

Tylenol (acetaminophen) is a pain reliever as well as a fever reducer. Tylenol is an over-the-counter medicine used to treat and reduce the symptoms of pain and fever caused by conditions such as colds or flu, headaches, muscle aches, arthritis, mensuration cramps, or fever.

We all think that medications should only be taken after eating some food, but some medicines can be consumed without food and are completely safe, like Tylenol.


Many people often confuse Tylenol with a non-steroidal anti-inflammatory drug (NSAIDs) like ibuprofen or Mortin, which leads them to stereotype Tylenol and consider it unsafe without being aware of the facts and working of the drug. Unlike NSAIDs, Tylenol is entirely safe to take on an empty stomach as it does not cause gastric or ulcer diseases. Tylenol may take up to twice as long to take effect if taken on full stomach, depending on the preparation. (Bushra, R., Aslam, N. and Khan, A.Y., 2011).

Interaction of Food with Tylenol

Interaction of Food with tylenol

Tylenol can be taken on a glass of water, as an empty stomach absorbs Tylneol much faster since there is no food. Food in our stomach deters the absorption process of Tylenol. However, many people might feel ill or uncomfortable after taking Tylenol on an empty stomach; these people might have a sensitive gastrointestinal tract. Taking Tylenol with some food might turn out to be better and much more comfortable (Bushra, R., Aslam, N. and Khan, A.Y., 2011).

How long does it take Tylenol to start working?

The time it takes for Tylenol to start working depends on the dose. Oral tablets must first dissolve in the stomach and get absorbed into the bloodstream before affecting the body. Tylenol liquid takes about 20 minutes to start working, whereas oral tablets take about 30 to 45 minutes. Tylenol taken on a full stomach may take up to double the time to affect the body, depending on the preparation. It takes more time for Tylenol to reduce fever while it is faster in relieving pain.
Know the best rates for Tylenol

Side effects of Tylenol

Tylenol can cause some side effects which create discomfort. These are some of the rare side effects, which include.

• Rash
• Itching or swelling on face, tongue, or throat
• Dizziness
• Trouble in breathing in some cases

Some widespread side effects of Tylenol are

• Nausea
• Loss of appetite
• May feel like hungover
• Dark urine

It is essential to go to a doctor if you have any side effects that bother you and are not ready to go away.

Precautions to be taken before Consuming Tylenol

Precautions to be taken before Consuming Tylenol
  • You should not take Tylenol if you are allergic to acetaminophen or if you have severe liver conditions.
  • Do not consume this medicine until and unless it is recommended or prescribed by your doctor if you ever had liver disease or if you drink more than two alcoholic beverages per day. It is because alcohol combined with Tylenol can be hazardous and can cause severe side effects and discomfort.
  • Acetaminophen can pass to breast milk and may harm a nurturing baby. Asking a doctor is mandatory before using this medicine if you are pregnant.
  • This medicine is not be given to children younger than two years old without the advice of a doctor.


In the end, you have now learned facts about Tylenol that you might not have known before, and this blog may have cleared the stereotypes like taking Tylenol will destroy your liver, it a drug used to get high, and that if taken on an empty stomach it will damage your internal organs, that was clouding your judgment to take Tylenol on an empty stomach. Do you now know that what is the correct way to consume Tylenol? And who all can consume it? And the fact that Tylenol is completely safe to be consumed on an empty stomach. 

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