Tylenol and meloxicam are NSAIDs medication that treats pain and inflammation-related issues. Both Tylenol and meloxicam can be taken together as these drugs do not lead to any drug interactions.

Can Meloxicam be taken with Tylenol?

Meloxicam and Aleve (naproxen) are both nonsteroidal anti-inflammatory medications (NSAIDs) that are used to treat pain, fever, and inflammation. They're used to relieve mild to severe Pain from things like headaches, menstruation, migraines, arthritis, sprains and strains, and toothaches.

For moderate discomfort that is not controlled by NSAIDs alone, NSAIDs can be used with Tylenol (acetaminophen). It's advised to avoid taking more than one NSAID at a time because you'll increase your chances of suffering negative effects. Both Tylenol and meloxicam being NSAIDs can lead to some harmful effects. 

GI distress such as bloating, diarrhea, constipation, irritation of the stomach lining, nausea, and vomiting are the most prevalent side effects. NSAIDs also have an impact on renal function, slowing blood flow through the kidneys. They may induce salt and water retention, resulting in edema and excessive potassium levels. 

Some nonsteroidal anti-inflammatory drugs (NSAIDs) have a significant risk of cardiovascular thrombotic events such a heart attack or stroke. NSAIDs can also cause asthma, headaches, sleeplessness, and hives.

It is safer to take Tylenol with either meloxicam, but meloxicam and Tylenol should not be used together. Consult your doctor if the discomfort persists or worsens.

Study on Tylenol and Meloxicam Together

Research: this study was conducted by aRice University, Houston bU.S. Army Institute of Surgical Research, JBSA - Fort Sam Houston, Texas, USA.

Aim: The effects of acetaminophen and meloxicam on platelet aggregation and coagulation function in human blood samples were studied in this study.

Results: the results detected that Acetaminophen or meloxicam had no effect on PT or any Rotem measures. Platelet aggregation and a PTT were harmed by acetaminophen and meloxicam. Characterizing the effects of acetaminophen and meloxicam on bleeding in vivo requires more research (Martini AK, Rodriguez CM, Cap AP, Martini WZ, Dubick MA).

What is Meloxicam, and How does it Work?

Meloxicam, marketed as Mobic, is a nonsteroidal anti-inflammatory medicine used to treat pain and irritation caused by inflammation and enlargement, and hardness in the joints.

This medication can be either orally or injected into the veins. This medication works by preventing the synthetic Cyclooxygenase protein from doing its job, resulting in pain and edema are caused by prostaglandins (Noble, S. and Balfour, J.A., 1996).

What is Tylenol, and How does it Work?

Tylenol is a pain reliever, a nonsteroidal anti-inflammatory drug used to treat a variety of ailments, including muscular pain, migraine, sore throat, flu, arthritis, and more.

You can also Tylenol over the counter from certified online pharmacy.

It includes acetaminophen, an active chemical that recognizes the source of the Pain. It produces prostaglandins, which send a message to the brain and prevent Pain (AMEER, B. and GREENBLATT, D.J., 1977).

Forms and Strengths of Meloxicam 

Form: This medication's dose can come in the form of capsules, pills, or an injection

Strength: Suppository; 120 mg, 125 mg, 325 mg, 650 mg; Chewable tablets; 80 mg; Junior tablets: 160 mg; Regular strength: 325 mg; Extra strength: 500 mg (Noble, S. and Balfour, J.A., 1996).

Form and Strength of Tylenol

Form: This drug is available in tablet, caplet, capsule, and other forms and is suitable for adults and children.

Strength: Tablets 325mg, 500mg; Caplets containing 325 mg and 500 mg; Capsules 325 mg 500 mg 650 mg (AMEER, B. and GREENBLATT, D.J., 1977).

How to take Meloxicam? 

However, one can consume meloxicam with or without food under the doctor's guidance and surveillance. It is advised to take meloxicam at the same time every day (Noble, S. and Balfour, J.A., 1996).

How to take Tylenol? 

When symptoms remain, take 2 caplets every 6 hours. If not advised by a doctor, do not take more than 6 caplets in 24 hours. Unless instructed by a doctor, do not take for longer than 10 days (AMEER, B. and GREENBLATT, D.J., 1977).

Meloxicam Dosage                

The drug's dose for children must be discussed with a doctor since safety is paramount. Adults, on the other hand, should take their medications as follows:

In General Dosage

The recommended dosage for this drug is 15mg, which can be raised to 25mg with a doctor's approval.

  • In the case of hemodialysis

In the condition of hemodialysis, the dose is around 7.5mg.

  • In the case of adults with osteoarthritis

If diagnosed with osteoarthritis, the oral dose is around 7.5mg.

  • When it comes to rheumatoid arthritis

The recommended dose is 7.5mg.

Meloxicam medicine must be used exactly as recommended because an overdose of this drug can be fatal (Noble, S. and Balfour, J.A., 1996).

Tylenol Dosage 

Dosage in Tablets: This medication's recommended dosage ranges from 325mg to 500mg when taken orally.

Dosage in Caplets: This medication's recommended dosage ranges from 325mg to 600mg when taken orally.

Dosage in the Form of Capsule: Tylenol may be taken orally in doses ranging from 325mg to 500mg, much like tablets (AMEER, B. and GREENBLATT, D.J., 1977).

Meloxicam Overdose

Overdosage on this medication can be lethal and can lead to side effects such as drowsiness, dizziness, fatigue. Other than that can also be adverse, including gastrointestinal bleeding, renal failure, coma, which is considered to be a rare case (Noble, S. and Balfour, J.A., 1996).

Tylenol Overdose

Tylenol overdosage can be harmful. According to the US Food and Drug Administration (FDA), taking too much acetaminophen can harm your liver and lead to loss of appetite, nausea, vomiting, and loss of breath (AMEER, B. and GREENBLATT, D.J., 1977).

Side Effects of Meloxicam 

The side effects that occur may be common but, in rare cases, can be adverse. The symptoms are as follows:

Common Side Effects ​

The common symptoms that may occur are: 

  • Fatigue 
  • Diarrhea
  • Abdominal Pain 
  • Nausea

These are the side effects one may or may not experience.

Adverse effects

These symptoms are rare but can lead to severe effects. The symptoms areas 


  • Heart attack 
  • Stroke 
  • Epilepsy
  • Liver damage 
  • Increased blood pressure

Side effects of Tylenol 

The side effects can be standard or can even be adverse. The common symptoms can be as follow: 

Common symptoms 

  • Loss of appetite 
  • Vomiting or nausea 
  • Rashes

Adverse symptoms  

Adverse side effects can be a rare situation; however, in any case, consult the doctor. 

Who cannot take Meloxicam? 

  • Suffer from Difficulty in breathing 
  • Fever or any flu 
  • Skin blisters 
  • Swelling in any part of the body
  • Hives 
  • This medication can be considered as a high-risk drug as it can increase the potential of heart attacks, strokes, etc., and can be deadly if one is suffering from a heart-related issue.
  • It can be dangerous for persons who have certain cardiac or renal illnesses or drinking problems.

Who cannot take Tylenol? 

  • Liver problems: Do not take this medication if you have liver problems
  • Alcohol consumption: Do not use# this medication with alcohol or if you consume alcohol regularly.
  • Children under the age of two: If you are under the age of two, you should not take this medication.
  • Pregnancy: If you're expecting a child, talk to your doctor before using this drug.
  • Do not take any acetaminophen-containing medicine since it can lead to overdosing.


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