What is Metaxalone?

Metaxalone is a drug used in treating muscles. It works for the muscle and relaxes its pain. This tends to believe that the Metaxalone drug works to treat muscle pains. It is used in the physical treatment of the person to relax and cure the muscle tissues.

It is treated by obstructing the pain in the brain; it relaxes the skeletal muscle-related pains or injuries in the body.

The generic name is Metaxalone, and the brand name is Skelaxin. You can also buy Metaxalone online through an online pharmacy.

The drug class of Metaxalone is Skeletal muscle relaxants (Bruce, R.B., Turnbull, L., Newman, J. and Pitts, J., 1966).

What is Ibuprofen?

Ibuprofen is used as a drug in relieving different pains. It is one painkiller that can cure pains such as headaches, tooth pains, period cramps, muscle pains, and even arthritis.

It also makes the person by curing a cold, fevers, and minor aches that happen in the body. Generic name is Ibuprofen and brand name is Advil, Motrin, Nuprin. you can buy Ibuprofen online through trusted pharmacy.

The drug class of Ibuprofen is NSAID (Non-steroidal anti-inflammatory drug) (Davies, N.M., 1998).

Can Metaxalone and Ibuprofen be taken together?

It can be taken only after the doctor's prescription. This drug has similar effects on the body, which works on pain-related issues. But one works for muscles and the other works on the different pains in the body.

There were no interactions found if metaxalone and Ibuprofen were consumed together. It also doesn't mean; there are no real interactions; a person should consult a doctor for a preferred solution and the working process of the medicine in your body.

A study was conducted to know the outcome of two medicines used together, one with Ibuprofen plus placebo versus Ibuprofen and metaxalone.

For this study, 320 patients were distributed into two groups, to which one was advised to take Ibuprofen and placebo, whereas the other group was given Ibuprofen/metaxalone/baclofen/tizanidine.

It was observed for a week about their lower back pain. Group 1 was given ibuprofen 600mg (3 doses a day), and others were given Ibuprofen 600mg plus metaxalone 400 mg, tizanidine 2mg, baclofen 10 mg.

It does not have any other effect compared to the placebo. It has no interactions shown in pains (A Randomized, Placebo-Controlled Trial of Ibuprofen Plus Metaxalone, for Acute Low Back Pain).

How does Metaxalone work?

Metaxalone works by obstructing the pain in the brain, which relaxes the skeletal muscle-related pains or injuries in the body. It works on stiffness or spasms in the body, to which there are fewer pains, and the body can be moved freely (Bruce, R.B., Turnbull, L., Newman, J. and Pitts, J., 1966).

How does Ibuprofen work?

Ibuprofen works on the inflammation process in the body by obstructing the pain from the brain. It lessens the swelling created in the body, cures other pains, and works on fevers as well. For arthritis also, it can be used, but only after the doctor's prescription (Davies, N.M., 1998).

Forms and Strength











1- Tablet

100mg, 200mg, 400mg, 600mg, 800mg

2- Liquid

100mg per 5ml, 50mg per 1.5ml  (infants)

3- Capsule


4- Chewable tablet


Dosage of Metaxalone




800mg (3 to 4 times a day)


800mg (3 to 4 times a day)

Dosage of Ibuprofen




800mg per dose (3200mg max per day)

(4 doses per day)


It changes according to the weight

(Consult a doctor for a proper dosage)

(Liquid Form)

It should be taken after shaking the bottle well and consuming it through a proper dosing measurement suggested by the doctor)

(Chewing tablet)

Do not directly swallow unless it's appropriately chewed. All the medicines taken should be advised by the doctor to not have any side effects seen in the body later.

Side effects of Metaxalone

Severe side effects which can be seen are as follows:

  • Breathlessness
  • Face getting swollen up
  • Lips getting swollen up
  • Tongue starts to bulge a little
  • Infection in the throat or any other effects on the throat

You should stop and consult a doctor if the side effects have been seen, such as:

  • Slow breathing rate
  • Head feeling comparatively heavier
  • Fainting out
  • The color of the urine getting changed to yellow
  • Stomach ache

Normal effects which can be seen after consuming Metaxalone such as:

  • Feeling sleepy all-day
  • Weakness in the body
  • Feeling of puking
  • Mild headache
  • Feeling anxious about things

These are not the complete side effects; there might be others, too; it's better to consult a doctor if you feel any weird changes in your body.

Side effects of Ibuprofen

Severe side effects which can be seen are as follows:

  • Feels like Breathlessness
  • Face and throat getting swollen up
  • Allergies on skin
  • Heart attack or having a feel of heat stroke
  • Chest paining
  • Body parts getting numb

Call the doctor if you feel like

  • Vision getting blurred
  • Breathe rate getting low
  • Gaining weight or reducing
  • Rashes on skin
  • Stomach ache
  • Liver issues
  • Red blood is getting low
  • Kidney issues

Normal side effects which can be seen after consuming Ibuprofen

  • Gastric issues
  • Feeling of tiredness
  • Mild headache
  • Sleepy and weakness

If you Overdose on Metaxalone

If you have overdosed, get a medical emergency as soon as possible. If you feel like heart attacks or any related problems to which you are having severe issues, It is advised to consult a doctor if you have any unthoughtful effects in your body (Bruce, R.B., Turnbull, L., Newman, J. and Pitts, J., 1966).

If you Overdose on Ibuprofen

If you overdosed on Ibuprofen, then get a medical emergency to prevent it from becoming worse if you feel nausea, severe stomach aches, or puking blood. If you feel any other severe effects within your body, it is advised to consult a doctor as soon as possible (Davies, N.M., 1998).


Metaxalone and Ibuprofen do not have any interactions which can be harmful. But that doesn't mean you have to take it in an easier way; You should consult a doctor before taking any medicine.

There might be side effects that can be seen according to the body, so it's good to take advice from your doctor and have the medicine as prescribed.


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