Loratadine is an antihistamine which is used for allergies. It is sold under the brand name Claritin.

A study was conducted by Rodsarin Yamprasert et al. to determine the efficacy and safety of Loratadine compared with ginger extract. This study was a double-blind randomised control trial. It was conducted for six weeks and involved 80 people who were divided into two groups of 40 each. One group was given a ginger extract of 500mg and the other group was given Loratadine tablet, 10mg.

The efficacy of both drugs was measured using various parameters which were the Total Nasal Symptom Score(TNSS), rhinoconjunctivitis quality of life questionnaire (RQLQ) and cross-sectional area of the nasal cavity with acoustic rhinometry (ARM) while the safety of both treatments was measured through history taking of side effects, blood analysis and blood pressure measurements.

Both groups improved TNSS and RQLQ and did not have any statistically significant difference. Both groups had no effect on blood pressure and also had similar liver function, and renal function results from the blood analysis and were determined to be safe.

How Does It Work?

Loratadine is a non-drowsy antihistamine that works by blocking the effects of histamine which is a substance that causes allergic symptoms such as sneezing, running nose, hay fever, watery eyes and hives. Loratadine is an over the counter medication which can be gotten from any pharmacy.

Forms And Strengths

There are different forms of Loratadine medicine; the syrup, capsule and the tablet. The syrup formulation comes as 5mg/5mls strenght, the tablet as 5mg and 10mg while the capsule is 10mg.

Ways To Take Medicine?

Its important to follow your doctors instructions and those on the prescription label before consumption and if self-medicating, ensure to read the directions on the leaflet.

Loratadine comes in various forms. The liquid form of the medicine is more convenient for smaller kids while older children and adults can take the capsule or the tablet which is available as a chewable or disintegrating form.

When To Take?

There is no compulsory timing; Loratadine can be consumed before or after food. It is usually taken once a day unless otherwise directed by your doctor.

Precautions To Take With The Liquid Form

For proper dosaging of the syrup, the correct measuring spoon or the syringe must be used. If unavailable, one can be gotten from a nearby medical store. Do not use a regular kitchen spoon because it will be difficult to get the correct dosage.


Allergic Rhinitis


  • 10 mg once a day
  • Maximum dose: 10 mg/day


  • 2 to 5 years: 5 mg once a day
  • Maximum dose: 5 mg/day
  • Six years and older: 10 mg once a day
  • Maximum dose: 10 mg/day



  • 10 mg once a day
  • Maximum dose: 10 mg/day


  • 2 to 5 years: 5 mg once a day
  • Maximum dose: 5 mg/day
  • Six years and older: 10 mg once a day
  • Maximum dose: 10 mg/day

Who Should Avoid Taking Loratadine?

  • Do not give this drug to children less than 2 years old.
  • Do not use if you are allergic to it or its inactive ingredients.
  • Use with caution in cases of kidney or liver disease
  • If you have diabetes (Because it may contain sugar)
  • Breastfeeding women are not advised to take this medicine because it is excreted in milk.

What Are The Side Effects?

Few people experience side effects with loratadine.

Common side effects Rare side effects
Headaches Tachycardia
Nervousness Hypotension
Fatigue Change in bowel habit
Dry mouth Bronchitis
Somnolence Gastritis

Also, Read


Loratadine is an antihistamine which is used for the treatment of allergic rhinitis and urticaria.

It is relatively safe with no to few side effects however it is important to visit your doctor before taking the medication.

  • Yamprasert, R., Chanvimalueng, W., Mukkasombut, N. et al. Ginger extract versus Loratadine in the treatment of allergic rhinitis: a randomized controlled trial. BMC Complement Med Ther 20, 119 (2020). From https://doi.org/10.1186/s12906-020-2875-z Accessed on 10 January 2022
  • Nault, M.A., Milne, B. and Parlow, J.L., 2002. Effects of the Selective H1and H2Histamine Receptor Antagonists Loratadine and Ranitidine on Autonomic Control of the Heart. The Journal of the American Society of Anesthesiologists96(2), pp.336-341. From https://doi.org/10.1097/00000542-200202000-00018 Accessed on 9 January 2022


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