Is Celebrex For Fibromyalgia Effective?

celebrex for fibromyalgia
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Celebrex is an NSAID, a non-steroidal anti-inflammatory drug, also labeled as a prescription drug. As described by its placement in the class of anti-inflammatory drugs, Celebrex is primarily used to cure inflammatory conditions, particularly in adults. Within this frame of reference, it is meant to treat rheumatoid arthritis, osteoarthritis, acute pain, menstrual cramps, and ankylosing spondylitis.

The active ingredient of Celebrex is celecoxib, and Celebrex is the brand name. It is the drug provided in the form of capsules. Moreover, it has received the most severe warning from the FDA, the black box warning, due to its increased risk of gastrointestinal bleeding and cardiovascular events.

Doctors also prescribe it to relieve fibromyalgia, a chronic pain disorder about severe widespread pain in fibrous tissues and muscles accompanied by fatigue, sleep problems, and low mood.

How Fibromyalgia Occurs?

Medically fibromyalgia is referred to as “Idiopathic muscle pain” because the species causing it are still not known. The outbreak of fibromyalgia is more likely among females. Neither does fibromyalgia cause inflammation nor spotlight inflammation as a symptom.
However, its underlying causative factor includes chronic inflammation. The trigger factor involved in the onset of fibromyalgia includes recurrent reactivation of the herpes virus. Various factors can lead to fibromyalgia, given as follows.

  • Infection: Some bacterial or viral infections appear to trigger or sometimes aggravate the fibromyalgia condition.
  • Genetics: Hereditary factors also contribute to the development of fibromyalgia, making people more susceptible to it; thus, it appears to run in families.
  • Emotional or Physical Trauma: Post-traumatic stress disorder has also been a fundamental determinant of fibromyalgia.

Symptoms for Fibromyalgia

Several symptoms indicate the development of Fibromyalgia, but they vary from person to person. For a long time, it has been considered that certain psychological factors are responsible for fibromyalgia, but later research revealed that surgery, illness, or injury might trigger the condition.
Some of the common symptoms include;
Widespread muscle or joint pain,
The problem in staying asleep or sleeping

  • Fatigue
  • Stiffness
  • Tender areas of body parts, particularly the elbow, knees, & head, cause pain when touched.
  • Cognitive difficulties include difficulty concentrating, memory problems, and impaired ability to focus.

Is Celebrex For Fibromyalgia A Good Choice?

Although Celebrex is not approved to treat fibromyalgia, one of the recent studies reveals that the combination of celecoxib and famciclovir is effective and safe in treating fibromyalgia. The combination of both drugs [IMC-1] provides aggressive antiviral activity against the latent herpes virus, eventually actively counteracting its reactivation and infection, thereby providing a timely, short-lived treatment against fibromyalgia.

Case Study:

As per the National Library Of Medicine a study was conducted on 143 Fibromyalgia patient for 16 week in a placebo (Dummy Medicine) controlled trial environment. Patients were randomly given the combination of Celebrex and Famciclovir in 1:1 ratio (Equally) and the outcome was measured in 24 hour time span.

Results: Significant change was recorded to the patient of combined medicine as compared to placebo patient. Hence proving a better solution for fibromyalgia.

(Pridgen WL, Duffy C, Gendreau JF, Gendreau )

Celebrex for fibromyalgia is more predominantly used in females than in males, where the percentage is found to be 86.67% in females and 13.33% in males. However, Celebrex’s effectiveness for fibromyalgia is given as follows:

Sr #

Overall 

No. of People

Long-Term

No. of People

1

Not at all

1

Not at all

0

2

Somewhat 

12 

Somewhat 

3

3

Moderate 

9

Moderate 

3

4

High 

12

High 

8

5

Very high

3

Very high

3

Is Celebrex A Permanent Solution For Fibromyalgia?

Despite being the remedy for inflammatory conditions, you might see doctors recommending Celebrex as a treatment option for fibromyalgia, which is not an inflammatory condition. It is not an approved medication for fibromyalgia, but doctors sometimes prescribe it off-label to treat the condition. When a drug is used to medicate conditions other than it is approved, it gets the name of the off-label drug.

Because Celebrex is NSAID, it is a drug with analgesic properties (pain-killing). It can lessen the pain in people with fibromyalgia, eventually improving sleep but not ensuring a permanent solution for the condition. Generally speaking, fibromyalgia has no permanent cure, while various medications can help manage the symptoms. Celebrex is available online as well as from your nearest pharmacy. With the internet pharmacies with certification one can buy online or Celebrex over the counter.

A New Approach to Treat Fibromyalgia

If gastrointestinal problems like leaky gut, dysbiosis, and infections are underlying causes of fibromyalgia, then following major key steps can be effective for the long-term improvement of fibromyalgia. Apparently the combination can be a good treatment under a proper supervision of doctor. 

Some major recommendations to develop long-term relief from fibromyalgia include:

  • Avoid medication (antibiotics), chemicals, and foods irritating your gut.
  • Consume fermented foods such as yogurt.
  • Eat plenty of fermentable fiber like starches.
  • Consume glycine and broth-rich foods, for instance, tongue cuts of meat.
  • Manage your stress with mindfulness, meditation, or biofeedback.
  • Consider taking prebiotic and probiotic supplements.
  • Treat any intestinal pathogens, such as parasites, if present.
  • Acquire at least 7-8 hours of sleep every day.

Conclusion

Avoid using Celebrex without a doctor’s recommendation, particularly if you are pregnant. Before using Celebrex for fibromyalgia, it is necessary to know the reason behind the development of the condition. 

Moreover, it is advisable to use Celebrex for fibromyalgia when it involves pain as the primary symptom because NSAIDs like Celebrex are no different. from placebo, again done under supervision or else the combination treatment of Celebrex and famciclovir can be undertaken.

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