Celebrex is a nonsteroidal anti-inflammatory drug (NSAID) used to treat acute pain and inflammatory disorders caused by rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also used to lower menstrual cramps and migraines. The drug works by producing chemicals that reduce hormones causing pain and inflammation in the body. Celebrex is taken orally, and it shows its effects within an hour. Sometimes combination of celebrex and other medicines for fibromyalgia.

Talking about coffee, it is a fundamental source of caffeine and has physical and psychological effects. Most people take coffee in the morning and the evening and, in most cases, at the prescribed time by doctors for taking a dose of Celebrex. That’s why here the question arises, whether you should consume Celebrex and coffee together or not? And if you take them together? So, for more information, read the article carefully and explore all about the subject.

Why Should You Drink Coffee in Your Daily Life?

Taking a coffee in your daily life can be refreshing and soothing. If you take it in the morning, it can help you to get up and finish your chores actively. Several people have misconceptions that coffee is unhealthy, but the reality is different.

You may feel much happier and energized after having a cup of coffee. If you want to lose weight without getting any side effects, it will help you. Medically, you will decrease diabetes, gout, and certain cancer risks by taking coffee. It may also help you in improving heart and liver health.

Similarly, one can consume coffee and Celebrex together as coffee has those substances which enhance the solubility of those compounds in Celebrex that are difficult to dissolve in the body.

Can You Consume Celebrex And Coffee Together?

Without a doubt, the combination of coffee and Celebrex is perfect, but at the same time, it is not advisable to take them together in one go. There should be a time duration gap between them.

Although the period is not apparent, the recommended gap duration of taking coffee and the drug together is 1 hour. This way, the drug will perform well, and you will be safe from unwanted disadvantages caused by this medicine. Moreover, coffee will give you an energy boost, and the dizziness after taking medication will not come.

How Does Coffee Dissolve Components Of Celecoxib (Celebrex)?

According to studies, coffee is extracted from tea leaves and prepared using the sublimation method. Upon dissolution with coffee, Celebrex and coffee formed a molecular complex of caffeine-celecoxib substance. In this process, the celecoxib was dissolved in distilled water, and the molecular complex (caffeine-celecoxib) was set by using the HPLC strategy at a wavelength of 250 nm.

In dissolution studies, USP dissolution apparatus one was used for diluting a usual Celebrex capsule, and apparatus 2 for cutting caffeine-celecoxib in distilled water. The highest solubility rate, i.e 48% (mg/m), was obtained with caffeine-celecoxib molecular complex compared to the usual Celebrex capsule.

The molecular complex showed excellent results in dissolution and solubility. This study shows that coffee has agents that help enhance the solubility and dissolution of poorly dissolved compounds in Celebrex. (PubMed)

When Should  You Take Celebrex Before Or After Coffee?

There is not a perfect time for consuming medicine, if you experience side effects like vomiting, headache, stomach pain etc then you should keep a gap of minimum 1 hour to avoid the effects. The best thing is to take consultation for a better and clear view towards it.

Preventive Measures You Should Take

If you’re treating your diseases (specific arthritis), you must take extra care of what you consume. Therefore, you must consider certain things while taking Celebrex with coffee which will prevent you from side effects. These preventive measures are given below:

  • Do not take coffee and your dose more than two times a day.
  • Do not take other medicines with Celebrex besides consuming coffee.
  • Eat food before taking your dose, and then grab a coffee.
  • Avoid other narcotics, such as alcohol.
  • Do not drink strong coffee when you are on medications. The strength of coffee should be medium.
  • Your dose of Celebrex should also be low, i.e., 100 - 300mg.
  • Call your doctor if you notice sudden weight loss.
  • If you’re pregnant, do not consume coffee with medication.

Moreover, listen to your doctor’s prescription carefully and follow all those instructions and steps.

Side Effects

You can face adverse side effects if you are not taking something in the prescribed manner. Similarly, if you consume Celebrex and coffee by neglecting preventive measures, your negligence will lead to other side effects. These side effects are:

  • Severe headache
  • Stomach pain
  • Diarrhea
  • Intestines problem
  • Constipation
  • Hypertension

These side effects can make your disease even worse. Therefore, you should stop consuming coffee and consult your healthcare provider if anything serious happens to you for further treatment.


You should not worry about consuming coffee with Celebrex. Just take your dose according to the prescription, consume healthy eatables, exercise correctly, and get your medical reports done after a while. Apart from taking coffee with Celebrex, make it a part of your daily life. You will find a clear difference in your activities.


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