Flexeril (Cyclobenzaprine) vs Valium (Diazepam)

Flexeril (Cyclobenzaprine) vs Valium (Diazepam)

Muscle spasms are treated with Flexeril (cyclobenzaprine) and Valium (diazepam). Valium is also prescribed for anxiety, seizures, and alcohol withdrawal symptoms. Valium and Flexeril belong to separate drug classes. Valium is a benzodiazepine, while Flexeril is a muscle relaxant (Basmajian, J.V., 1978).

Which One is Better?

Cyclobenzaprine is a common treatment for muscular spasms that is also available as a generic, although it should not be used for an extended period. Valium is beneficial for anxiety and muscle spasm when used infrequently or for a short period. Valium is particularly fast-acting when compared to cyclobenzaprine.

Difference between Cyclobenzaprine and Valium

Valium and cyclobenzaprine belong to separate pharmacological classes. Valium is a benzodiazepine and cyclobenzaprine is a muscle relaxant.

Diarrhea, rash, exhilaration, loss of balance, excitability, muscle spasm, lack of sleep, rage, and speech issues are some of the side effects of Valium that differ from cyclobenzaprine (Aker, P., 2004).

Similarities between Cyclobenzaprine and Valium

Cyclobenzaprine and Valium are both used to treat muscle spasms. Side effects of cyclobenzaprine and Valium that are similar include drowsiness, fatigue, vision problems, and confusion (Elenbaas, J.K., 1980).

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Age Restrictions

For Cyclobenzaprine-Cyclobenzaprine is not recommended for children under the age of 15.

For Diazepam- Use is not recommended for children under the age of six months.

Conditions Treated

By Cyclobenzaprine

  • Relaxes muscles
  • Relives pain from strains
  • Relives pain caused by sprains
  • Relives pain caused by muscle injuries
  • Chronic Myofascial Pain
  • Fibromyalgia
  • Migraine

By Valium 

  • panic disorder
  • a feeling of restlessness with the inability to sit still
  • symptoms from alcohol withdrawal
  • psychosis caused by sudden alcohol withdrawal
  • inducing of a relaxed, easy state
  • muscle spasm
  • anxiety

Availability and Cost

Flexeril (Cyclobenzaprine) vs Valium (Diazepam)

Cyclobenzaprine

Cyclobenzaprine pills are available in three dosage strengths.

  • 5 milligrammes (mg)
  • 7.5 milligrammes (mg)
  • 10 milligrammes (mg) tablets

Cyclobenzaprine is also available as a generic or under the brand name Amrix in 15 mg or 30 mg extended-release capsules.

Dosage for muscle spasms 

For adults and teenagers 15 years and older – For muscle spasms, take 5–10 mg up to three times per day as required for up to three weeks.

Maximum recommended dosage – For a maximum of three weeks, take no more than 10 mg three times each day.

Amrix and Fexmid are two brand names for cyclobenzaprine. Depending on the drugstore you visit, cyclobenzaprine oral tablet 10 mg costs roughly $10 for a supply of three tablets.

Valium

Valium (diazepam) comes as an intramuscular injection, an intravenous injection, and a tablet. It’s usually prescribed as a tablet, and it’s taken that way.

The tablet is available in the strength of

  • 2mg
  • 5mg
  • 10mg

Intramuscular injection: the amount varies. Intravenous injection: the amount varies.

Dosage 

For Adults to treat muscle spasms – 3-4 times a day, take a 2-10 mg pill.

For children six months and older – The standard dose is 0.1 to 10mg a day, and the maximum dose is 30mg.

Diazepam is a generic name for Valium. Valium oral tablet 2 mg costs roughly $364 for a 100-tablet supply, depending on the drugstore you go to.

Mechanism of Action

Cyclobenzaprine

Cyclobenzaprine is a centrally acting skeletal muscle relaxant with a tricyclic antidepressant-like structure. Cyclobenzaprine reduces localized skeletal, muscular spasms without impairing muscle function.

According to research, it predominantly functions in the brain stem of the central nervous system. Although an overlapping action on the spinal cord may contribute to its total skeletal muscle relaxant activity, cyclobenzaprine does not work directly on skeletal muscle or the neuromuscular junction. 

The evidence suggests that cyclobenzaprine causes a decrease in tonic somatic motor activity, impacting both the gamma() and alpha() motor systems. According to recent research, cyclobenzaprine is a (5-HT2) receptor antagonist, and its antispasmodic activity is due to this extra action.

Valium

Valium is a benzodiazepine that has anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnestic properties. The majority of these effects are assumed to be due to a facilitation of the action of gamma-aminobutyric acid (GABA), a central nervous system inhibitory neurotransmitter.

How to take them?

Cyclobenzaprine

Cyclobenzaprine is available as a tablet and an extended-release capsule for oral administration. The tablet is normally taken three times a day, with or without food. 

The extended-release capsule is typically taken once a day, with or without food. Do not take this medication for longer than three weeks without consulting your healthcare professional. 

Follow the instructions on your prescription label carefully, and if there is anything you don’t understand, ask your doctor or pharmacist to explain it to you. 

Take cyclobenzaprine exactly as prescribed by your healthcare professional. Do not take more or less of it, or take it more frequently than your doctor has suggested.

Valium

With a glass of water, take diazepam tablets or liquid. They can be consumed with or without meals.

Typically, you’ll take your medicine one to three times per day.

Your healthcare professional will determine the most appropriate dose for you. It’s critical to take diazepam exactly as prescribed by your doctor (Hall, A.M., 2017).

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Common Side Effects

Cyclobenzaprine

  • Blurred vision, Dry mouth, or Throat.
  • Headache.
  • Fatigue.
  • Loss of appetite.
  • Stomach pain.
  • Drowsiness.
  • Dizziness.

Valium

  • Drowsiness
  • Tiredness
  • Dizziness
  • spinning sensation
  • Exhaustion
  • Constipation
  • ataxia (loss of balance)
  • memory issues
  • Constipation

Drug Warnings

Cyclobenzaprine

Serotonin syndrome is a potentially fatal side effect of this medication. This occurs when your body produces too much serotonin due to your drugs. If you have any signs of this ailment, contact your doctor immediately. Agitation, hallucinations, convulsions, and nausea are some of these symptoms. If you combine cyclobenzaprine with other drugs that enhance the risk of serotonin syndrome, such as antidepressants, your risk may be increased.

This medication has the potential to cause cardiac arrhythmias. If you use a depressive medication or already have cardiac problems, your risk may be increased. These problems can lead to a heart attack or stroke if they aren’t addressed.

Valium

Diazepam has the potential to become addictive. Do not take a higher dose, take it more frequently, or take it for a longer period than your doctor recommends.

Tell your doctor if you’ve ever drunk a lot of alcohol, if you use or have used illicit drugs, or if you’ve ever taken too many prescription prescriptions.

During your treatment, refrain from drinking alcohol or using illegal substances. When you drink alcohol or use illegal substances while taking diazepam, you increase your chances of developing these significant, life-threatening side effects.

Also, tell your doctor if you are currently suffering from or have ever suffered from depression or a similar mental disorder.

Diazepam, especially if taken for several days to weeks, can create physical dependency. Do not stop taking this drug or reduce your doses without consulting your doctor.

Stopping diazepam abruptly might aggravate your health and create withdrawal symptoms that can last anywhere from a few weeks to over a year. Your healthcare professional will most likely progressively reduce your diazepam dosage (Hincapie-Castillo).

Scientific Study

In patients with long-term intractable pain of cervical and lumbar origin increased by skeletal muscle spasm and soreness, the effectiveness of cyclobenzaprine hydrochloride, a novel tricyclic skeletal muscle relaxant, was demonstrated. The study compared cyclobenzaprine hydrochloride (10 mg three times a day) to diazepam (5 mg three times a day) and placebo in a double-blind, randomised trial.

The 16 patients in the cyclobenzaprine group showed an overall improvement in pain variables after two weeks of treatment, as did the 16 patients in the diazepam group. In the trial, no significant side effects from cyclobenzaprine were observed. However, the anticholinergic activity of cyclobenzaprine caused dry mouth and mild sleepiness, which were more common than with diazepam or placebo (Jackson, J.L. and O’Malley, P.G., 2001).

Robaxin vs. Valium

Robaxin vs. Valium

Robaxin (methocarbamol) belongs to the Skeletal Muscle Relaxant class of medicines. It is a prescription drug used to treat muscle cramps caused by pain or injury and Tetanus symptoms. Robaxin can be taken alone or in combination with other medications.

Valium (Diazepam) belongs to the benzodiazepine class of medicines. It’s used to treat anxiety, withdrawal from alcohol, and seizures. It’s also used to treat muscle spasms and sedatives before medical procedures. This medicine calms the brain and nerves.

Differences Between Robaxin And Valium

Different skeletal muscle disorders are treated with Robaxin (methocarbamol) and Valium (diazepam). Robaxin is used to treat skeletal muscle conditions, including pain or damage combined with rest and physical therapy, while Valium is used to treat muscle spasms. Valium is also used to treat anxiety, convulsions, and alcohol withdrawal symptoms (Wei, S.U.N., Chong-hui, L.I., Liang-sheng, W.A.N.G. and Si-lan, D.A.I., 2010).

Robaxin and Valium are two different types of drugs. Valium is a benzodiazepine, while Robaxin is a muscle relaxant.

While they may have similar side effects like nausea, constipation, memory issues, loss of balance or coordination, blurred or double vision, dizziness, some side effects might differ between Robaxin and Valium.

Side effects of Robaxin that are different from Valium include stomach upset, vomiting, flushing (warmth, redness, or tingly feeling), sleep problems. In contrast, Side effects of Valium that are different from Robaxin include drooling, dry mouth, slurred speech, or loss of interest in sex.

conversation on robaxin and valium

Dosages

For Robaxin: Except in the case of tetanus, the total adult dosage should not exceed 30 mL (3 vials) each day for more than three days. A similar course may be followed following a 48-hour drug-free gap if the problem persists. 

One dose of 1 gram may be sufficient to alleviate mild symptoms. Additional doses of 1 gram may be repeated every 8 hours up to a maximum of 3 g/day for no more than three days in the most severe cases or in postoperative settings where oral administration is not possible.

Taking Valium alongside other sleep aids or medications that restrict your breathing can result in serious side effects or death. Consult your doctor before using opioid medication, a sleeping pill, a muscle relaxant, prescription cough medicine, or anything for depression or seizures. 

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Drug Interactions

Patients should be aware that Robaxin might produce drowsiness or dizziness, making it difficult for them to drive. Because Robaxin has a general CNS-depressant impact, patients should be mindful of the potential for adverse interactions with alcohol and other CNS depressants. 

Notify your healthcare professional if you are taking other products that cause drowsiness, such as opioid pain or cough relievers, alcohol, marijuana, drugs for sleep or anxiety, other muscle relaxants, or antihistamines.

Taking Valium alongside other sleep aids or medications that restrict your breathing can result in serious side effects or death. Consult your doctor before using opioid medication, a sleeping pill, a muscle relaxant, prescription cough medicine, or anything for depression or seizures.

Other pharmaceuticals, such as prescription and over-the-counter medications, vitamins, and herbal items, may interact with diazepam. Concomitant use with alcohol is not suggested due to the amplified sedative impact.

What Happens If You Take Robaxin And Valium Together?

Robaxin vs Valium

When Valium is used with Robaxin Side Effects: 

  •  Dizziness
  •  Drowsiness
  •  Disorientation

 Some people, especially the elderly, may have difficulty thinking, judging, and physical coordination. While using these medications, you should avoid or limit your alcohol use. Also, until you know how the prescriptions affect you, avoid tasks that need mental attention.

Which One Is Better - Robaxin or Valium?

Many healthcare professionals prefer Robaxin over Valium because it has been thoroughly researched. It’s also less expensive and sedating than some other solutions. In recent studies, 44 percent of people who took methocarbamol for up to 8 days experienced total pain relief (compared to 18 percent who did nothing) – and this was without any significant side effects.

Benzodiazepine drugs such as Valium are often prescribed as muscle relaxants. However, these aren’t really preferred because they don’t function as effectively as they should, are sedating, and can lead to addiction.(Simpson, M.H., Managing Cancer Pain.)
Soma vs Valium

Soma vs Valium

Soma is the brand name for the prescription drug carisoprodol, a muscle relaxant that has sedative properties that dampen the central nervous system. Doctors often prescribe Soma in conjunction with rest and physical therapy to relieve muscle tension and pain associated with injuries such as sprains and strains. The drug was approved in the year 1959 in the United States for medical purposes.

Valium was patented in the year 1959 by Hoffmann-La Roche. The drug was one of the most frequently prescribed medications in the world since its launch. It is recorded in the World Health Organization’s List of Essential medicine.

The blog will give you analytical data about Soma and Valium.

What are the Key Differences between Soma vs Valium

What are the Key Differences between Soma vs Valium
  • Soma is used for muscle and joint pain. At the same time, Valium is used for multiple purposes like anxiety, seizures, alcohol withdrawal syndrome, benzodiazepine withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome.
  • Soma comes in the form of tablets. Valium comes in a variety of dosage forms like tablets, oral solution, rectal gel, injectable solution, and intramuscular devices.
  • The lowest price for Soma is $6.78, and for Valium, the lowest cost is $6.74 (depending upon the pharmacy).
  • Valium injection starts acting in just 1 to 5 minutes. On the other hand, Soma takes at least 30 minutes to start acting.
  • Soma helps relax the muscle, but Valium helps to relax you.

Difference between their Dosages

For Soma-
The usual adult dosage can go around 250 to 350 mg orally 3 times a day and at bedtime.
The duration of this therapy should be 2-3 weeks.

For Valium-
Valium is used for many purposes.

• For Management of Anxiety Disorders and Relief of Symptoms of Anxiety- Depends upon the severity of symptoms, the dosage can go around 2mg to 10 mg, 2-4 times a day.
• For Symptomatic Relief in Acute Alcohol Withdrawal- 10 mg, 3 or 4 times during the first 24 hours, reducing to 5 mg, 3 or 4 times daily as needed.
• For Adjunctively for Relief of Skeletal Muscle Spasm- 2 mg to 10 mg, 3 or 4 times daily.
• For Adjunctively in Convulsive Disorders- 2 mg to 10 mg, 2-4 times daily.
• For Geriatric Patients, or in the presence of debilitating disease- 2 mg to 2.5 mg, 1 or 2 times daily initially; increase steadily as required and tolerated.

The dosage should not be compared or go against what your healthcare provider has prescribed to it. Every person needs a different amount of dosage depending upon the person’s age, gender, medical conditions, etc.

soma-Vs-Valium
Affordable Soma (Carisoprodol) available

Warnings of Soma vs Valium

  • Inform your doctor about your past and current medical conditions, including which medications you are on.
  • Never misuse or abuse any drugs, it can lead to addiction or adverse effects.
  • The drugs are for a short period only. Do not extend the duration unless your doctor has told you to do so.
  • Take the drug as prescribed by your health care professional. Always follow the physician’s advice.
  • If in case you miss any dose, take it immediately but make sure it is not time for your next dose. Do not double dose.
  • The drugs have the potent to make you feel sleepy, so avoid alcoholic beverages while on the medications and do not work on any hazardous machinery unless you feel you are fine to take the task.
  • Do not discontinue taking the drugs on your own. If you want to stop the intake, first discuss with your physician, they will provide a safe way to reduce down the drugs.

For Pregnancy and Breast feeding

soma and valium for pregnancy and breastfeeding

Soma-
Soma is not recommended for pregnant women. It should be used only if the Gynaecologist feels that the benefit can out weight the possible risks.
Soma is Excreted into human milk. Like pregnancy, for breastfeeding, the drug is not recommended. If, in any case, it has been given, caution should be taken, and the infant should be monitored for signs of sedation.
Valium-
The drug is not recommended for pregnancy and breastfeeding. It can be only used if the Gynaecologist believes that the benefit can overweight the possible risks. The infant should be kept under supervision for any changes.

Conclusion

Both Soma and Valium are the first preference for most doctors when it comes to managing muscle spasms. In fact, Soma is one of the most common medications that doctors recommend for muscle spasms. Valium causes more activity in the body than Carisoprodol leading to more side effects. Relaxation of muscles released with Valium: this is a side effect that makes no sense in Valium. Any of the drugs or sometimes none of the drugs may not be effective for some people. If you don’t feel any positive changes in your body after taking the drug, consult your doctor; your doctor may prescribe another drug for you. Always stick to your doctor’s direction and never share your medicine with anyone(Leonard, P. and Valaer, C., 2014).