Flexeril in the Treatment of Back Pain

Flexeril in the Treatment of Back Pain

Flexeril is a medication that can treat back pain and is considered a frequently prescribed medication. Flexeril treats pain, injury, or muscle spasm-related conditions as a muscle relaxant. This drug is primarily used during the resting period and ongoing physical therapy treatment. 

Flexeril for backpain

How Does Flexeril Treat Back Pain?

Flexeril is a medication that works by interrupting the transmission of nerve impulses (or pain sensations) to the brain. To treat muscle spasms produced by painful circumstances such as an injury, Flexeril is combined with rest and physical therapy. Thus, Flexeril treats pain-related issues ranging from back pain to joint pain through this mechanism of action.

Flexeril Dosage For Back Pain

The recommended dose of Flexeril is 5 mg three times a day. The dosage of the medication may increase to 10 mg three times a day, depending on the patient’s response. Flexeril should not be taken for more than two or three weeks at a time.
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Flexeril Efficiency In Treating Back Pain

Research: This study was conducted by the Department of Medicine, National Naval Medical Center, Bethesda, MD, USA.

Aim: To conduct a systematic observation of the efficacy of Flexeril in the treatment of back pain.

Method: This study was evaluated by Searched outcomes from MEDLINE, PsycLIT, CINAHL, EMBASE, AIDS LINE, HEALTH STAR, CANCERLIT, the Cochrane Library, Micromedex, Federal Research in Progress, and the references of reviewed articles for English-language, randomized, placebo-controlled trials of Flexeril in adults with back pain.

Result: In the treatment of back pain, cyclobenzaprine is more efficient than placebo; however, the benefit is limited and comes at the cost of additional side effects. The effect is most significant within the first four days of treatment, implying that shorter treatments may be preferable (Chaffee DM. Cyclobenzaprine in the Treatment of Low Back Pain).

Adverse Side Effects Of Flexeril

Adverse Side Effects Of Flexeril 

One might experience certain adverse effects after taking this medication however is a rare case. Suppose detected any contact the doctor as fast as possible. 

  • Dizziness
  • Drowsiness
  • Light-headedness
  • The mouth feels dry
  • Blurred vision

Common Side Effects Of Flexeril 

The common side effects are namely as follows:

  • Bloating and gas are less prevalent adverse effects.
  • Indigestion
  • Vomiting or nausea
  • Constipation or discomfort in the stomach
  • Constipation
  • Diarrhea
  • Nervousness or excitement
  • More frequent urination 
  • Headache

Conclusion

Flexeril, a muscle relaxer, is used in conjunction with rest and physical therapy to treat muscle spasms caused by acute muscle and skeletal disorders. It’s only meant to be taken for a few weeks. The muscle relaxant Flexeril) is a typical medicine for low back pain that is used to relieve muscular spasms in addition to non-narcotic analgesic pain management. However, studies have shown that improvements in low back pain symptoms occurred at all recorded periods, with a more significant effect observed in the first four days of therapy as unfavorable effects would indeed persist beyond the first few days. Thus, Flexeril treats back pain however comes with certain side effects (Chaffee DM. Cyclobenzaprine in the Treatment of Low Back Pain).
The Efficacy of Diclofenac in the Treatment of Migraine

The Efficacy of Diclofenac in the Treatment of Migraine

Diclofenac is effective for relief from migraine. It is a very common drug used in day-to-day routine by migraine patients. It is also available widely across the entire country and around the world.

Diclofenac is a phenylacetic acid derivative that has anti-inflammatory, antipyretic, and analgesic properties through inhibition of COX-1 and COX-2 activity and prostaglandin synthesis.  Diclofenac is a potent COX inhibitor, with activity 3–1000 times greater than other NSAIDs. These actions relieve migraine (Gan, T.J., 2010. Diclofenac: an update on its mechanism of action).

chat with doctor to treat migraine

Scientific study for Treatment of Acute Migraine Attack With Diclofenac

In a double-blind placebo-controlled experiment comprising 86 migraine patients, the efficacy of diclofenac sodium, a powerful prostaglandin inhibitor, was examined in patients with acute migraine attacks.

Forty-six patients with acute migraine attacks were given a 75 mg diclofenac sodium intramuscular injection, while another forty individuals were given a paracetamol intramuscular injection.

The diclofenac sodium group experienced partial or complete relief of pain and other symptoms of an acute migraine episode within 10 minutes of treatment, while the paracetamol group experienced relief within 32 minutes.

In 40 patients (88 percent), complete alleviation of the attack was achieved within 30 minutes after diclofenac sodium, compared to 7 patients (17.5 percent) in the paracetamol group. Side effects were uncommon and minor.

In conclusion, diclofenac sodium given intramuscularly is a highly effective treatment for acute migraine attacks (McNeely, W. and Goa, K.L., 1999. Diclofenac-potassium in migraine).

diclofenac vs paracetamol infographic

Dosage forms and Strengths

Diclofenac potassium

  • Packet-50 mg (1 packet) in 30-60 mL of water, mixed well, and drunk immediately
  • Tablet-50 mg
  • Capsule-25 mg

Diclofenac sodium

1.Tablet, delayed release

  • 25mg (generic)
  • 50mg (generic)
  • 75mg (generic)

2.Tablet, extended-release

  • 100mg (generic)

Diclofenac is not for prophylaxis but only for an acute attack of migraine. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals.

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Who can and cannot take diclofenac?

Most adults can take diclofenac. Diclofenac is not suitable for some people. To make sure it’s safe for you, tell your doctor or pharmacist if you:

  • Have ever had an allergic reaction to diclofenac or any other medicines.
  • Have an allergy to aspirin or other non-steroidal anti-inflammatory medicines (NSAIDs) such as ibuprofen or naproxen.
  • Have ever had side effects from taking NSAIDs, such as wheezing or other signs of asthma, a runny nose, swelling of the skin (angioedema), or a rash.
  • Have ever had stomach ulcers, bleeding in the stomach or intestines, or a hole in your stomach.
  • Have high blood pressure (hypertension).
  • Have heart failure, severe liver disease, or kidney disease.
  • Are pregnant, planning to get pregnant, or breastfeeding.

What if I take too much?

Taking more than your prescribed dose of diclofenac tablets, capsules or suppositories can be dangerous. It can cause side effects such as:

  • Stomach Ache
  • Feeling or Being Sick (Vomiting)
  • Diarrhea
  • Black poo or Blood in your vomit – a sign of Bleeding in your Stomach
  • Headaches
  • Drowsiness
  • Ringing in your Ears (Tinnitus)

Contact your doctor if you consume more than required or visit a hospital near you for proper management.

Conclusion

Diclofenac Sodium is a generic medication that is used to treat mild to moderate pain as well as the signs and symptoms of osteoarthritis and rheumatoid arthritis. Ankylosing spondylitis can also be treated with diclofenac sodium. Menstrual cramps can be treated with several brand-name versions. Diclofenac Sodium is also known by the names Diclofex DC, Voltaren, Solaraze, Voltaren Gel, and Pennsaid.

Does Aspirin Help with Headaches?

Does Aspirin Help with Headaches?

Aspirin is a group of salicylate acid and classified into Non-steroidal anti-inflammatory drugs. That is used to treat fever, pain, and any inflammation in our body. Moreover, it is an OTC medication. OTC (over-the-counter) means the prescription is unnecessary to buy this drug (Patrono, C., 2001. Aspirin).

How does Aspirin help with Headaches and Migraines?

Aspirin is a drug that can control the prostaglandin hormone level; having a high level of prostaglandin level leads to an increase in pain, fever, and inflammation. So the drug aspirin is helpful to reduce prostaglandin levels. The drug inhibits the chemical reaction in our body and serves as an anti-inflammatory, analgesic drug (Aspirin for acute treatment of episodic tension‐type headache in adults).
conversation of two people on headaches

Scientific study on the efficacy of Aspirin

A randomized, double-blind, placebo-controlled research looked at the efficacy of a single 1000-mg dose of Aspirin for treating acute moderate to severe migraine with or without aura. 409 of the 485 participants took study medicine, and 401 had a verified migraine attack (201 with Aspirin and 200 with placebo). At 2 hours, 20% of aspirin-treated subjects were pain-free, compared to only 6% of placebo-treated subjects. The rate of headache recurrence was 21.8 percent for Aspirin (23 of 105 patients) and 27.7% for placebo after 24 hours (19 of 68 subjects). At 24 hours, only 34% of aspirin-treated participants required rescue medication, compared to 52% of placebo-treated subjects.  Aspirin was well tolerated, with no significant differences in adverse events between groups (Efficacy and safety of aspirin, and caffeine in alleviating migraine headache pain).

Dosage for headaches

When you have a severe headache, immediately reach out to your doctor based on your pain and frequency.

  •  900 – 1300 mg used for onset use of headache.
  •  81 – 325 mg used for daily usage of headache.

Forms and Strengths of Aspirin

Aspirin is available in a range of forms and strengths, such as:

  • Tablet – 81 mg, 325 mg, 500 mg
  • Tablet, delayed-release – 162mg, 325mg, 500mg
  • Tablet, chewable – 75mg, 81mg
  • Tablet, enteric-coated – 81mg, 162mg, 325mg, 650mg
  • Gum, chewing, oral – 227mg
  • The extended-release capsule – 162.5mg

Common side effects

Does Aspirin Help with Headaches

Aspirin also has some side effects, so it is necessary to talk to the doctor about the dosage and frequency of the drug before taking medicine. It is not recommended for children under 16 years.

  • Nausea
  • Vomiting
  • Stomach bleeding
  • Drowsiness.

Conclusion

Aspirin is a drug that helps to relieve mild to moderate levels of headache. Before using the medication, it is recommended to consult the doctor.

Is Toradol Useful To Treat Migraine?

Is Toradol Useful To Treat Migraine?

Yes, Toradol is the medication that can treat migraine; however, it is not FDA approved for the treatment related to migraine or headache-related issues. This medication is often used off the table for migraine. This medication acts as abortive therapy; it can stop the pain after the migraine starts its action(Rowe, B.H., 2013).

Study: Toradol For Migraine And Its Effectiveness

Is Toradol Useful To Treat Migraine

Study: Toradol effectiveness For migraine.

Research: This study was conducted by the 1Department of Surgery (Emergency Services), University of Texas Medical Branch, Galveston. 

Objective: To examine the effectiveness of Toradol for migraine. 

Method: this experimentation was conducted by gathering Twenty-three patients who presented in the emergency department and were previously diagnosed with migraine.  

Result: out of 23 patients, about 17 patients experienced relief from pain and discomfort due to acute headaches. The effectiveness lasted for 6 hours when injected directly into veins. 

Conclusion: Toradol works efficiently for pain relief from migraine.

conversation of two people on migraine

Dosage Toradol

This medication should only be taken according to the prescribed Dosage and under the physician’s guidance. The Dosage for Toradol for migraine is as follow: Toradol is a popular NSAID medication that treats migraine, pain, and inflammation. The advised Dosage for the treatment of migraine is as follows(Conlon, P., 1998):

Intravenously

The Dosage intravenous is about 15mg to 30mg per day.

Intramuscular

The Dosage in the case of Intramuscular is 60mg which can be further increased to 120mg, however, under the medical practitioner.

Do not overdose on this medication in any case, as it can lead to serious effects.

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How Long Does Toradol Take To Work?

Toradol is a medication that works by blocking the naturally occurring substance which causes pain. Toradol proceeds to the mechanism of action quickly. It takes about 30mins after administration. Its full impact takes about 1-2 hrs, and the effects last for 6-7hrs, often prescribed for acute migraine or for post-recovery therapy(Poretsky, L., 1995).

Other Side Effects

Other than migraine, there are other side effects that can be adverse or common.

Adverse Side Effects

  • Fainting
  • Palpitation heartbeat
  • Ringing in the ears
  • Mental/mood problems (confusion, despair)
  • Persistent/severe headache
  • Stomach pain
  • Visual changes

These are a few adverse effects; consult the doctor immediately.

Common Side Effects

  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea
  • Gas 
  • Dizziness

These are a few side effects that can fade away in side effects.

Medication Other Than Toradol

Aside from Toradol and other NSAIDs, you can opt for these medications:

  • Rizatriptan (Maxalt)
  • Zolmitriptan (Zomig)
  • Sumatriptan (Imitrex)
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Other Medicines For Migraine.

Other than Toradol, there are several different medications that are precisely used for or are effective in working against migraine. They are namely:  

  • Tylenol  
  • Aspirin 
  • Naprosyn 
  • Ibuprofen  
Does Tylenol Help with Cramps?

Does Tylenol Help with Cramps?

Tylenol is also known by the generic name Acetaminophen is a pain reliever and a fever reducer. There are several brands and forms of Acetaminophen available, and Tylenol is one of them. Tylenol is used commonly among people since it’s an over-the-counter drug. Tylenol can be used for the following reasons:

  • Headache.
  • Arthritis.
  • Backache.
  • Toothache.
  • Sore throat.

These were a few common conditions for which Tylenol gives us relief. Tylenol isn’t meant for children below 12 years of age without a doctor’s recommendation, and an adult shouldn’t exceed 4000mg of Acetaminophen in a day. An irregular dose could result in a hazardous overdose.

conversation of two people on Cramps

How does Tylenol work?

Research is ongoing to know how Tylenol actually works. We know how it reacts with the human body, however. It is considered a Non-opioid analgesic.  A Non-opioid analgesic works by impeding an enzyme known as cyclooxygenase (COX). COX works as a catalyst for converting fatty acids stored in cell walls-arachidonic acid- to substances called Prostaglandins. Prostaglandins serve various protective functions in the body that can also cause pain, inflammation, and fever. After a cell injury, the prostaglandin causes pain by several mechanisms. The impairment occurs in the peripheral nervous system, where the nerves are outside the brain, spinal cord, and central nervous system. They increase one’s body temperature by affecting the brain’s heat-regulating region, also called the hypothalamus. During any injury, prostaglandin causes us pain. Still, the Tylenol blocks the COX, which stops the subsequent production of prostaglandins in the central and peripheral nervous system (Botting, R.M., 2000. Mechanism of action of acetaminophen)

How does Tylenol help with Menstrual Cramp?

According to a study by the wright state University School of Medicine and College of Science and Engineering, Dayton, Ohio, USA. It was a four-month study where 90 women participated. No pain relievers were given to them in the first two periods; however, during the last two periods, they were given a dose of 2 x 325 mg aspirin, Acetaminophen (Tylenol), or an identically packed placebo. These medicines were given to them every 4 hours to a total of eight tablets during the first 24 hours of their periods, beginning with spots. For a statistical analysis period, 1 and 2 were combined on an average and then compared to the average of periods 3 and 4. The number of days of flow, total menstrual loss in grams, pain were examined by MANOVA for the three treatment groups. An ANOVA type of analysis was also done for each of these variables for the first 3 menstrual days. The MANOVA reading failed to show any significant differences from all 3 variables. The same was for the ANOVA reading except for the variable pain of cramps. To see the difference in the measurement of cramps, the Duncan’s Multiple Range Test for pain was used, which showed us that the average pain of the placebo group was higher than the average pain of the aspirin group and Tylenol (Acetaminophen) group. This concludes that neither aspirin nor Acetaminophen (Tylenol) given in the doses changes either total menstrual loss or the pattern of loss during the first 3 menstrual days. But, when it came to cramps, both the drugs proved to be an effective means to alter the pain (Pendergrass, P.B. Effect of small doses of aspirin and acetaminophen on total menstrual loss and pain of cramps).

Tylenol dosages for Cramps

Tylenol dosages for Cramps

Tylenol is an over-counter drug available in:

  • Capsules,
  • Gel caps,
  • Chewable,
  • Liquid,

Adults and teenagers weighing at least 110 pounds (50kgs) should not take more than 1000mg at one time and not more than 4000mg per day.

Why Ibuprofen is better for Menstrual Cramps?

Menstrual cramps take a toll on women and are a significant concern for them. One out of two people suffers from extreme menstrual cramps. Although menstrual cramps are really intense from the age of 20-24, they weaken as a women ages. Many analgesics help relieve menstrual cramps like ibuprofen and Tylenol. When we compare the 2, ibuprofen is similar to Tylenol, which helps relieve pain and fever. Still, Ibuprofen has inflammatory properties, which makes it a better drug to relieve menstrual cramps. The recommended dosage is 400 mg of ibuprofen taken every six to eight hours for the initial days of the period. Any queries regarding the drug, dosage, or uses, the pharmacist will assist you (Chan, W.Y., Dawood, M.Y. and Fuchs, F., 1979).
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Conclusion

Although menstrual cramps are a typical symptom of menstruation, they can be dealt with using the correct medication and can be under control. Consult your General Practitioner regarding the same and drug usage.

Tylenol’s Efficacy and Safety in the Treatment of Migraine

Tylenol’s Efficacy and Safety in the Treatment of Migraine

The generic name for Tylenol is acetaminophen which is used as a fever reducer and a pain reliever. Tylenol is an over-counter drug available in capsules, gel caps, chewable, liquid, and suppositories. Adults usually use two 325 mg capsules every 4 to 6 hours and not exceeding ten tablets in 24 hours. 4000mg is the maximum an adult can consume. Before consumption of the drug, it is advisable to consult your General Practitioner. (Hynninen, M.S., Cheng, D.C., Hossain, I., Carroll, J., Aumbhagavan, S.S., Yue, R. and Karski, J.M., 2000)

conversation of two people on migraine

How does Tylenol deals with a Migraine?

Research is still going on to know how Tylenol works. We know what it does to the human body, however. It is considered a Non-opioid analgesic. A Non-opioid analgesic works by obstructing an enzyme known as cyclooxygenase (COX). COX works as a catalyst for converting fatty acids stored in cell walls-arachidonic acid- to substances called Prostaglandins. 

Prostaglandins serve several protective functions in the body but can also cause pain, inflammation, and fever. After a cell injury, the prostaglandin causes pain by several mechanisms, primarily where the damage occurs in the peripheral nervous system where the nerves are outside the brain and spinal cord and in the central nervous system. They increase one’s body temperature by affecting the brain’s heat-regulating region, which is also called the hypothalamus.

During a headache, we face a similar function where the prostaglandin causes us pain. Still, the Tylenol blocks the COX, which stops the subsequent production of prostaglandins in the central and peripheral nervous system. Hence resulting in relief when it comes to migraine. (Lipton, R.B., Baggish, J.S., Stewart, W.F., Codispoti, J.R. and Fu, M., 2000)

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Effects of Tylenol on Migraine

Effects of Tylenol on Migraine

According to a study done by the Department of Neurology of the Albert Einstein College of Medicine of Yeshiva University, most people treat their migraine headaches with over-the-counter medication. A treatment used by incorporating Tylenol is very sparse.

The study was based on a randomized, double-blind, placebo-controlled oral consumption of Tylenol (acetaminophen). 1000mg (two 500mg extra-strength Tylenol tablets) with an identical placebo to treat a single acute migraine attack. Patients who met the international headache society diagnostic criteria with or without aura were included. Patients who needed bed rest with their headaches or vomited more than 20% of the time were excluded.

After 2 hours, the headache rate for the patients who took Tylenol was 57.8% in the acetaminophen group and 38.7% in the placebo group. Pain-free rates after 2 hours were experienced by 22.4% in the acetaminophen group and 11.3% in the placebo group. The average pain intensity difference from the baseline after 2 hours was 1.08 in the acetaminophen group and 0.73 in the placebo group. At 2 hours, other migraine disabilities also significantly improved.

The research was concluded by stating that Tylenol (Acetaminophen) was very effective in treating pain, photophobia, headaches, and functional disability in mild cases of migraines, excluding the people with severe cases of migraines. The drug also had a good safety profile and was tolerated correctly. (Lipton RB, Baggish JS, Stewart WF, Codispoti JR, Fu M)

Conclusion

Around 1 billion people worldwide suffer from a migraine, and a part of them use over-the-counter drugs to treat it. These headaches/migraine needs to be treated carefully and with the help of medical care. Acetaminophen, i.e., Tylenol overuse, is more common than you think. Frequent use of such drugs could lead to severe cases of headaches and dependency on them. To avoid such a thing from happening, it is advisable to use it in moderation and seek professional help when required. 

Aspirin for Toothache | Is it the Right Choice?

Aspirin for Toothache | Is it the Right Choice?

Aspirin is an NSAID (nonsteroidal anti-inflammatory drug. It was the first NSAID to be ever discovered. NSAID’s are a class of drugs that help relieve pain, lower inflammation, and reduce fever.

Aspirin contains a salicylate compound that is found in plants such as myrtle and willow tree.  Aspirin is used to treat many conditions, especially to manage pain and swelling, while also reducing the dangers of heart attack and strokes in patients with high risk.

 

Aspirin for Toothache Is it the Right Choice

In general, aspirin is used to treat mild to moderate pain and swelling and health issues such as:

  • Tylenol for Cold and flu
  • Tylenol for Migraine and Headaches
  • Tylenol Menstrual cramps
  • Arthritis and migraine
  • Sprains and strain
two people conversation about asprin for toothache is a right choice

How does Aspirin Work?

Aspirin is an antipyretic (fever reducer), analgesic (pain reliever), and anti-inflammatory (fights swelling and inflammation). As mentioned before, aspirin is an NSAID. Like other NSAIDs, aspirin also chemically addresses the nerve signals by blocking the effects of certain enzymes that create prostaglandins, meaning less pain and minor swelling. In addition to this, aspirin can also reduce the risk of heart attack and strokes. Aspirin works to stave off the platelets in your blood from clumping and clotting your arteries, escalating the blood flow to your brain and heart. (Vane, J.R. and Botting, R.M., 2003. The mechanism of action of aspirin)

Can Aspirin be used for Toothache?

The leading cause of toothache is swelling inside the tooth. However, unlike other swellings on your body, the swelling inside your tooth hurts more. This is because the surrounding tooth structure is rigid and not flexible/ expandable. This means that the swelling inside your tooth has got nowhere to go. This pressure that you feel inside your tooth is what you call toothache and is the thing that makes you feel like your tooth is about to explode.

People often think aspirin can cure your toothache. It is pretty accurate, but this common misconception is that placing an aspirin on your tongue can relieve your pain. Placing aspirin on your tooth or gums only allows the aspirin to dissolve into your bloodstream slowly. This is an inferior way to ingest aspirin into your system.

The generic name of aspirin is Acetylsalicylic Acid, which explains the corrosive effects that the tablets possess. Placing aspirin on your gum causes chemical burns to take place. Being an acid, it will start to attack your enamel. If this process is repeated, severe erosions may occur. The aspirin begins to burn your gums as well as your cheeks if placed on the gums. It will usually look like some of the gums and cheek tissues have turned white, which in reality is burn damage. (Seymour, R.A., 1983. The efficacy of self-prescribed analgesics in the treatment of toothache)

The proper way to take aspirin to treat a toothache is by swallowing it. Aspirin works by being ingested. Once the tablet is in the stomach, it starts to make its way through the body and bloodstream. Aspirin relieves the aches by blocking the pain signals from being sent to the brain. The way it helps is by interrupting the pain chemicals in the bloodstream.

Doctors prescribe a 600mg dosage of aspirin every two hours to treat toothache. This would mean you will have a four-hour gap between each dosage; however, do not take more than the daily dose as recommended on the box. New research has found out that aspirin holds a few dental benefits despite its concerns. Taking low dosages of aspirin repairs damaged cavities in the tooth. A research team in British found that aspirin can enhance the function of stem cells located in the teeth. Aspirin also increases the expression of genes that work to form dentin (the primary structure of the teeth damaged by decay). (Faisal, M.D: a potential plant for treatment of toothache)

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Conclusion

So yes, aspirin can help deal with toothache but only if swallowed and not by placing it on your tongue. There are also many other treatments available to treat toothache. You should see a dentist if your tooth starts aching too much. To take proper care of your teeth, book a dental checkup appointment every six months to ensure your oral health.

Does Aspirin Help with Lower Blood Pressure?

Does Aspirin Help with Lower Blood Pressure?

How does Aspirin Work?

Aspirin is a drug commonly used to get relief from minor aches, pains, and fevers. It is also used as a blood thinner or an anti-inflammatory medication. Without a prescription, aspirin can be purchased over-the-counter. Aspirin is the world’s first nonsteroidal anti-inflammatory medication (NSAID). An Aspirin is not a steroid but has similar properties. Aspirin isn’t suitable for everyone and could have undesired side effects when a person is in pain; the nerves present in their damaged tissue signal the brain. The brain, in return, sends a message to the damaged tissue to release certain chemicals called prostaglandins which is a hormone that makes the tissue swell up. This process also intensifies the signal process to the brain, which results in feeling more pain. Here is where aspirin comes into the picture. The drug is used to block the signals hence reducing the pain. Aspirin also helps thin the blood, which reduces the swelling to an extent. (Vane, J.R. and Botting, R.M., 2003. The mechanism of action of aspirin)
two people conversation on aspirin help with lower blood pressure
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What is High Blood Pressure?

When the force of your blood pushing against the walls of your veins is constantly high, it is called Hypertension (high blood pressure). Our tissues and organs need oxygenated blood. The nerves supply the oxygenated blood to our body parts. When our heart beats, it creates pressure that pushes the blood through our nerves, reaching our organs. This pressure is our blood pressure, which contains two forces, the systolic pressure, which pumps out the blood out of the heart to the arteries, and the diastolic pressure, where the heart rests between heartbeats. These two pressures represent the blood pressure in numbers. (American Heart Association, 2017. What is high blood pressure?)

Aspirin for High Blood Pressure

aspirin for high blood pressure
High blood pressure, also known as Hypertension, is a problem that quite some people face. If not treated immediately, high blood pressure can cause nerve damage, heart damage and affect your brain. A Spanish study shows that taking aspirin at night is more effective than taking one in the morning. This study included 328 people with stage 1 high blood pressure; the patients were 44 years old. The patients were divided into three groups, group 1 was given no aspirin, group 2 was given 100mg of aspirin in the morning, and group 3 was given 100mg of aspirin in the night. All patients’ blood pressure was monitored every 20 minutes during the day and every 30 minutes at night. The results were as follow: • When you take aspirin at night, your blood pressure drops significantly. • When you take aspirin first thing in the morning, your blood pressure rises somewhat. • Without aspirin, blood pressure is somewhat lower. (Hermida, R.C., Ayala, D.E., Calvo, C. and López, J.E., 2005)

Aspirin for Lower Blood Pressure

Low blood pressure, also known as Hypotension, can seem desirable, and for some people, it may not cause any problem. But abnormally low blood pressure can cause dizziness and feel weariness. In extreme cases, low blood pressure can be life-threatening. Aspirin is a drug that is used to relieve pain, fever, etc. The drug can also be used as an anti-inflammatory or a blood thinner. When a person has low blood pressure, their heart doesn’t pump the blood to the organs via the veins with much force, causing them to feel dizzy or lightheaded. According to a study done by the population health sciences of the University of Wisconsin medical school, published by the National Library of Medicine, Nonsteroidal anti-inflammatory drugs usually are taken to increase blood pressure. Still, it has been recently proven that aspirin lowers blood pressure. Trials conducted suggest that aspirin taken at bedtime lowers blood pressure in a controlled and unmasked way. It also opposes past studies by showing an 18% increase in the risk of Hypertension among regular users. Short-term use of aspirin isn’t harmful and doesn’t seem to interfere with other antihypertensive medication. Hence stating the benefits of aspirin is undesirable for high blood pressure. (Effects of intensive blood-pressure lowering and low-dose aspirin in patients)

What are the Other ways to Cope up with Low Blood Pressure?

ways to cope up with low blood pressure

Low blood pressure isn’t much of a significant concern normally but should be taken care of to avoid other complications that it may cause later on. Following are a few ways to cope with low blood pressure:
• Using more salt.
• Drinking more water.
• Medications.
• Wearing compressed stockings.
• Implementing lifestyle changes.
• Getting a good night’s sleep.
• Exercising regularly.

Side effects of Aspirin

All medicines have their share of side effects, and aspirin also has side effects, although not everyone may experience them. Following are a few side effects:

Common Side Effects:

  • Slight Indigestion.
  • Bleeding more than usual. Since aspirin thins your blood, it can make you bleed more easily.

Serious Side Effects:

  • Rashes, peeling of the skin.
  • Coughing up blood. 
  • Blood in your stools.
  • Liver problems.
  • Swollen limbs.
  • Serious allergic reaction.

 

It is advisable to seek immediate medical care if one experiences such symptoms. Consult a doctor before taking any medications and be thorough with your symptoms for a speedy recovery.

Is Robaxin Effective on Headaches?

Is Robaxin Effective on Headaches?

Although not proven that Robaxin is effective for headaches but, some clinical experiments suggest that Robaxin, when combined with other medications, can be effective on headaches. A seventy-five-year-old, 60 kg woman without significant medical history, presented to the Long Island College Hospital Emergency Department with an acute inferior wall MI in 1990. The patient was discharged from the hospital on day five with a regimen of isosorbide dinitrate, diltiazem, metoprolol, and aspirin. The patient remained well until November, 1990, when she began to experience headaches. By February, the patient felt well except for an occasional headache, which responded to acetaminophen. Isosorbide dinitrate was discontinued. In early June, the patient noticed an increase in frequency and intensity of the headache, and more disturbing was a charge in its character, which was described as a bitemporal squeezing with radiation to the sternocleidomastoid muscles bilaterally. Methocarbamol and acetaminophen were prescribed. By late June the headaches were intolerable, now associated with dizziness, and the patient underwent CT of the brain which disclosed a large left SDH. There was no history of head trauma, alcohol abuse, or seizure disorder. (Case Report)
two people conversation on robaxin effective on headaches

How to consume Robaxin

how to administer Robaxin
Robaxin should be taken exactly as directed by your doctor. Read all drug guides or instruction sheets and follow all guidelines on your prescription label. Robaxin oral is a medication that is taken by mouth. After the first two or three days of treatment, you may need to reduce your dose. Follow your doctor’s dosing recommendations carefully. Robaxin injection is delivered as an infusion into a vein or as a muscle injection. This injection will be given to you by a healthcare provider. Before starting the oral form, the injection is normally administered as a single dosage. When the medicine is injected, tell your caretakers if you have any burning, pain, or swelling around the IV needle. (Uccellani, E.L., 1960)

Dosage in Different age groups

For the first 48 to 72 hours, adults with musculoskeletal discomfort should take three 500 mg capsules by mouth four times a day, then two tablets four times a day to keep spasms at bay. If using 750 mg tablets, take two pills by mouth four times a day for the first 48 to 72 hours, then one tablet every four hours or two tablets three times a day to keep spasms at bay. Injections are given every 8 hours at a dose of 1 gram intravenously or intramuscularly, with a maximum of 3 grams a day for three days. For Tetanus spasms in adults, inject 1 to 2 grams intravenously every 6 hours as needed, up to a maximum of 24 grams per day. In children, inject 15 mg/kg intravenously every 6 hours as needed. For three days, the cumulative dose should not exceed 1.8 g/m2. (Boakes, J., Peach, J.P. and McGill, S.M., 1998)

Side effects of Robaxin

Is Robaxin Effective on Headaches

Robaxin has the potential to induce major adverse effects, such as:

  • Convulsions
  • Lightheadedness
  • slow heartbeats
  • Fever
  • Chills
  • flu symptoms 
  • skin or eye yellowing (jaundice)

If you think you have a side effect that worries you or does not go away, tell your doctor.

The common side effects include:

  • Headaches, vertigo, and sleepiness;
  • Fever
  • Confusion and memory issues;
  • Nausea, vomiting, and stomach pains;
  • Double vision
  • Flushing (a sensation of warmth, redness, or tingling);
  • Insomnia (sleep deprivation)
  • A lack of cooperation
Say goodbye to headaches with Robaxin

Safety Measures

  • This drug should only be taken during pregnancy if necessary.
  • This medication may cause dizziness, drowsiness, or blurred vision. You may become dizzy or sleepy if you consume alcohol or marijuana (cannabis). Do not drive, operate machinery, or perform any other activity that requires alertness or clear vision until you can do so safely.
  • Tell your doctor or pharmacist about your medical history, especially if you have liver problems.
  • Inactive substances in his product could cause allergic reactions or other difficulties. For further information, speak with your healthcare professional.
  • The drug’s adverse effects, particularly disorientation, dizziness, and sleepiness, may be more noticeable in older persons. These side effects can make you more prone to falling.
  • Tell your healthcare professional if you use other products that cause drowsiness, such as opioid pain or cough relievers, drugs for sleep or anxiety, other muscle relaxants, or antihistamines.
Musflex Pills

Musflex Pills

Nowadays, pain in the neck, back, and joints is widespread among people worldwide, especially in the U.S.

The primary reason is the changing lifestyle of working professionals. If you are one of those suffering from such conditions, Musflex pills can give you comfort.

They are muscle relaxers, and can be beneficial in the cases of contracting or twitching muscles. Generally, the doctors prescribe acetaminophen or ibuprofen as a counter medicine first. If their treatments are not relaxing, you can get a prescription of Musflex pills.

Musflex-Pills

What is Musflex?

Musflex is an analgesic that consists of Carisoprodol and Naproxen. These pills are used to get relaxation from short-term pain. Carisoprodol is a synthetic derivative that relieves musculoskeletal pain (due to muscular changes or movements of body parts). It is available generically and also sold under the brand name Soma.

Carisoprodol is an FDA-approved drug. Its chemical composition is C12H24N2O4, and its synonyms are Carisoprodate, Carisoprodatum, etc. Frank Berger was a pharmacologist who invented it in June 1959 at Wallace Laboratory.

What are its Side Effects

When you intake Carisoprodol for muscle pain, it produces meprobamate that works to keep your body calm. But, the consumption of Musflex pills without prescription or its abuse can be dangerous because it might become addictive for some people.

Musflex-Pills

These medicines may generate cravings in you. They have comparatively less risk of adverse health effects due to overdose, but they have some side effects, which are following-

  • Dizziness
  • Drowsiness
  • Headache
  • Tiredness
  • Fast heartbeat
  • Dryness in mouth
  • Vomiting
Ease muscle pain with Carisoprodol at an inexpensive price

Warnings For Medication

Avoid its medication if you have porphyria.

Pregnant or breastfeeding women should consult their doctor before taking it.

  • Keep it away from children, or else it will cause significant issues if they swallow it.
  • People who consume alcohol will feel drowsier. Avoid alcohol during the medical routine.
  • Don’t continue the medication for longer than three weeks.
  • Please don’t stop the dosage suddenly; reduce it gradually.

Is Carisoprodol Anti-inflammatory?

The non-steroidal anti-inflammatory drugs (NSAID) restricts the body from producing inflammatory chemicals. They can reduce fever and effective arthritis pain, back pain, cramps in the stomach, etc.

Carisoprodol is an antipyretic and anti-inflammatory analgesic. The duration of action of this drug is 4 to 6 hours. It is also used in combination with aspirin for pain relaxation. Aspirin is also a non-narcotic analgesic with antipyretic and anti-inflammatory properties.