Diclofenac And Tylenol – Can We Combine It Together?

Diclofenac And Tylenol – Can We Combine It Together?

Medications have different varieties, and each has its effectiveness for the condition. When medications are combined or taken together, it can increase strength regarding the issue or vice versa. 

Diclofenac and Tylenol have different mechanisms of action and are also used to treat various conditions. What if it is combined and used? Let’s see, but first, a short teaser of them.

Diclofenac And Tylenol ( A short teaser)

Diclofenac is NSAID(Non-steroidal Anti-inflammatory drug) used to treat pain from arthritis, rheumatoid arthritis etc.

It blocks the production of pain-inducing hormones called COX1 and COX2 and relieves the pain. Diclofenac is available over the counter. Buy Diclofenac online from a certified online pharmacy. (Todd, P.A. and Sorkin, E.M., 1988)

Tylenol also known as Acetaminophen is a pain reliever which helps in menstrual pain, headaches, fever etc. It blocks the enzymes that produce prostaglandin in the brain(a pain chemical) and stops the pain signals from reaching the brain. Buy Tylenol online from a trusted and reputed online pharmacy.  (Ameer, B. and Greenblatt, D.J., 1977)

Observing keenly, we get to know that the medicines can stop pain arising from different conditions. So We can make a combination to increase the power of medicine. Is it possible?

Diclofenac And Tylenol: Useful Or Not?

Firstly, let’s clear your doubts about interaction. This mixture found no interaction in this combination. However, it doesn’t mean it cannot affect your health. You should notify your healthcare consultant before usage.

Mixing Diclofenac and Tylenol can be compared to two machines working for a single cause in their respective mechanism. Diclofenac relieves the pain by stopping cox one and cox2, which helps in decreasing the inflammation and swelling of the muscles and bones.

In contrast, Tylenol inhibits the prostaglandin in the brain to reduce the body’s temperature. Together they make an effective way to treat conditions or issues. We can say that the combination is successfully treating pain.

Can We Use Diclofenac And Tylenol For Long Term Purpose?

When you decide on its long term use, ask yourself and your doctor is it essential?. Generally, it is not recommended for long term usage as it can cause stomach bleed, ulcers, diarrhea, and increased unknown side effects.

Any medicine or combination of medication should be thoroughly discussed and consumed as per the prescription. Remember, you are a patient, not a self expert.

Who Cannot Use This Combination Of Diclofenac And Tylenol?

People who are allergic to painkillers have sensitive guts, heart conditions etc., should not use this medicine.This combination is prescribed to selected ones due to their condition and examined circumstances.

Some people still use it to escape their issues quickly without observing their effects on themselves. It can increase the weakness and strengthen the side effects on the body.

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Does Diclofenac + Tylenol(Acetaminophen) Interact with each other or other?

There were no severe interactions found in this combination, but they can interact with other medications and can harm the system

If you are consuming Tylenol and Diclofenac together, the medicines you should not consume with these two are mentioned below:

  • Aspirin
  • Antipsychotic drug
  • Blood thinners
  • Anti- Gout
  • Anti Cancer medicines 
  • Alcohol
  • Hypertensive drugs
  • Anti-Diabtetes medicines

Side Effects Of Diclofenac plus Tylenol

Forms And Dosages of Diclofenac


  • Tablet- 50mg
  • Delayed release tablet -25mg, 50mg, 75mg
  • Extended release tablets-100mg
  • Capsules-18mg, 25mg, 35mg
  • Oral solution-50mg
  • Injection -37.5mg

Dosage of Diclofenac for Rheumatoid arthritis and Osteoarthritis

14 years and older:

Diclofenac Potassium

  • 50mg (Gap of 8 to 12 hours)

Diclofenac Sodium

  • 50mg (gap of 8 hours) or
  • 75mg (12 hours)


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Precautions that a person should take before consuming Diclofenac

  • Avoid usage if you are allergic to diclofenac
  • ACE Inhibitors should be avoided
  • People who are 75 years or older in age are not recommended to use for long period
  • Alcohol and Cannabis should be avoided.
  • Notify doctor if you are consuming any hypertensive drug

Caution: Pregnant ladies should avoid using diclofenac and breastfeeding women too. They should take advice from their healthcare before using it.

Forms and Dosages of Tylenol

Tylenol is available in tablet and liquid form. Strengths of tablet form are 325mg, 500mg and 625mg. Whereas liquid gel consists of 325mg.

Dosage Of Tylenol


  • Two tablets of 500mg at a gap of 4 to 6 hours.
  • Max dose up to 4000mg per day.

Disclaimer: Only ten days recommended.


  • 325-650mg of 1 dose at a 4-6 hours gap.
  • Max dose up to 3250mg a day.

Disclaimer: Dosage might differ according to age and weight.

Precautions that a person should take before consuming Tylenol.

If the person 

  • consumes alcohol three times a day
  • has extreme liver damage.
  • is pregnant. (patient should take it only after advice)
  • is less than two years of age
  • Is suffering from malnourishment.
  • is having kidney problems.
  • is allergic to Tylenol.

Caution: If a woman consumes Tylenol while breastfeeding, it might cause an issue for the kid. The Tylenol drug gets mixed up with milk and can be harmful to the child.

What Is The Dosage Of Diclofenac And Tylenol?

Your health expert prescribes Diclofenac and Tylenol combination doses as per your health status. Combination medicines sometimes prove effective, and the same can cause side effects.

It is better to follow the advice. For a short idea of the dose, one can take two tablets every 6 hours of a gap of 24 hours. Again the dose should be well consulted by your physician.

How Long Does Diclofenac+Tylenol Stay In Your System?

Tylenol has a half-life of 2-4 hours and gets eliminated after 24 hours. Diclofenac has a half-life of 2-3 hours and wears off in 15 hours through urine.

When combined, the peak absorption time also differs. There is no fine study about how much it stays in your system but certain studies help us know it can last for two days in the system.


The combination is the new era of increasing the strength of medicine to relieve pain. The combination can be beneficial as well as yield unwanted situations. Diclofenac and Tylenol together are helpful in pain management.

The interactions are below the possibilities. Then too, the user has to be aware of both medicines’ side effects.  Always take advice before trying any mixture. And always ask the question!

Can you take Methocarbamol and Tylenol Together?

Can you take Methocarbamol and Tylenol Together?

A combination of Methocarbamol and Tylenol can be taken as per the doctor’s advice. It doesn’t have many side effects, but to be in a safe zone, a person should consult a doctor before having it. This might have side effects such as a feeling of headache, feeling of having a deep sleep, fainting, and maybe lightheadedness.

Methocarbamol is a drug used for making the muscles relax. It is used in treating pains more effectively on body muscles. It treats various issues in the body like injuries, spasms, and different muscle-related problems.

Methocarbamol is a generic name, whereas the brand name is Robaxin; muscle relaxers are a drug class. It is not an over the counter medication though you can get Methacarbamol online from a certifed online pharmacy but it is recommended to get doctors advise first.

 Tylenol is used in treating various aches in the body, which causes pains. It helps in lessening the pains and fevers. Tylenol has a generic name as Acetaminophen, whereas Tylenol is a brand name.

It is mainly known in the USA. It is an over-the-counter drug, which can be readily available. you can even buy Tylenol online from certified pharmacy.

Why Methocarbamol is used for?

Methocarbamol is a relaxer for muscle pains and spasms. It is used in the treatment for getting the muscles cured. Spasms and muscle pains happen for overusing weights or any aches which are caused due to various reasons.

Why Tylenol is used for?

Tylenol is a medicine used for mild pains; it even cures fevers and colds in the body. It helps cure different aches and works for headaches, period cramps, and even arthritis.

A Study on Methocarbamol and Acetaminophen Together

Study: J Clin conducted this study from the Korean Society for Clinical Laboratory Science.

Aim: To observe the relaxation of pains after taking Methocarbamol + Ibuprofen compared to Methocarbamol + Acetaminophen.

Method: There were patients involved in the study who were facing different issues. This study was made for 7 days. Pains varied from mild to high. People were divided into 3 groups; the first group was given the combination of Acetaminophen and Ibuprofen consisting of 325mg tablets and 200mg tablets. The second group was given Acetaminophen, methocarbamol, and Ibuprofen which consisted of 325mg+500mg+200mg tablets. The third group was given methocarbamol and Acetaminophen consisting of 325mg+500mg, including body stretches 3 times a day.

Results: After all the completion of observing patients, the conclusion was like; Body pains were similar to every other combination included in the study. In other senses, Consuming Methocarbamol and Tylenol (Acetaminophen) showed the same results in curing pains by stretching the body parts and managing the pains.

conversation of two people on methocarbamol and tylenol

How does Methocarbamol work?

As Methocarbamol is a muscle relaxer, it works by the feeling of pain, which can cause many aches to the body and muscles by stopping it and obstructing it to send signals to the brain. It helps in curing the pains caused by various reasons.

How does Tylenol work?

As Tylenol is a pain reliever, it helps cure the pains throughout the body. It works by stopping the body from creating various pains. It works in lowering the body temperature; it is an analgesic and even antipyretic. 

What is Methocarbamol treated for?

Methocarbamol is treated for various muscle spasms in the body to which the person might have pains. It is mainly used in physical therapy and other related treatments.

What is Tylenol treated for?

Tylenol is a drug used in treating different body pains ranging from mild to moderate. It helps cure issues such as headaches, toothaches, fever, and cold.

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Forms and strengths






Tablet form

500mg, 700mg


Injection form

100mg, per ml


Tablet form

325mg, 500mg, 625mg


Liquid form


How should you take Methocarbamol?

For taking methocarbamol, a person should take all the required guidelines from a doctor or read the package. It is said that a person can take medicine with food or without food intake.

How should you take Tylenol?

Before taking medicine, you should keep in mind the procedure and how to have it by the doctor’s consultation. It is said that a person can take the medication with or without food intake, but the person should have enough water intake. 

Ways to take Methocarbamol

There is one type of medicine, whereas the other form is an injection

  • Tablet form can be taken by swallowing with a water
  • The doctor can only give the injection form of treatment.

Ways to take Tylenol

There are two forms of taking a medicine

  • Tablet form which has to be swallowed with water
  • The liquid form has to be placed at the point of pain.


Methocarbamol (Tablet)

Adult (18-64 years)

Pediatric (16-17 years)

Senior Citizen (65 years and more)


Dosing at the start-

It has to be taken 1500mg per dose (6000mg per day)

Starting dosage-

It can be taken (6000mg dose) 1500mg per dose

As per the age

Senior citizens have a weaker body, It leads to kidney issues

Continuation of dose- A person can take 4000mg -4500 mg per day (Dividing as per the doctor’s recommendation)

Continuation of Dose-

The person is recommended to have 4000-4500mg per day

Kidney doesnt work fast Due to the age, which will make the medicine in stomach stay for a longer time

In severe cases- 8000mg can be used.

It might vary from patient to patient.

Doctor would recommend it as per the patient’s condition.

Doctor might recommend only if needed, that too at a very low dose.

Methocarbamol (Tetanus)



Dosing at start-

1 to 2g followed by 1 to 2g

(should not exceed 3g)

Dosing at Start-

At every interval of 4-6 hours, 15mg can be given

It can also be given by diluting into water and inserting into the body

Maximum dose can be continuously taken at 1.8 g/m2/day IV for 3 days.

24mg should be the maximum dose according to the body reaction

If needed further, a doctor’s recommendation is mandatory.





In every 4-6 hours, 2 medicines can be consumed of 500mg

In every 4-6 hours 325mg to 650mg can be consumed

Max Dosage should not increase 4000mg per day

Max dosage should not  increase 3250mg per day

Only 10 days advisable

(Consult a doctor)

Dosage may vary from their age and weight

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Side effects (Methocarbamol)

Usual side effects which can be seen after consuming Methocarbamol

  • The person might feel having a mild headache
  • The person might feel sleepy or out of energy
  • The person might feel their head getting a little heavy
  • The person might feel sober

Serious side effects which can be seen after consuming Methocarbamol

  • The person might feel breathlessness, and even chest might pain
  • The person might feel specific areas getting swollen up
  • The person might feel having a heart attack or low blood pressure
  • The person might get the place swollen where the injection was inserted.
  • The person might feel things in yellow, maybe eyes and body
  • The person might think that his memory is getting lost or forgetting things
  • The person might have visionary issues, such as blurring

If the person faces any issues within them, the first duty is to consult a doctor for immediate guidance. Mild matters can be ignored but not up to the mark till you get those things to worsen for yourself. Get a medical emergency. It is always good to consult a doctor for a better purpose and health.

Side effects (Tylenol)

Usual side effects which can be seen after consuming Tylenol

  • The person might face allergic issues
  • The person might see rashes on their body
  • The person might feel itchiness in the body
  • The person might think that their mouth and throat are getting swollen up
  • The person might feel sleepy all day and tired
  • The person might face urinating dark in color
  • The person might get pains which have never been caused before
  • The person might think that the body and eyes are getting yellow

Severe effects which can be seen after consuming Tylenol

  • The person might feel unstable in their stomach
  • The person might start getting a feeling of kidney issues
  • The person might feel reduced in blood count because of insufficient oxygen flow into the body.

Severe effects should be first consulted to the doctor, to which it can get into control. Normal effects also be known to the doctor to prevent more issues on the person’s body.

What if I Overdose on Methocarbamol?

Overdose can result in panic and getting drowsy. If it happens to you, you should first consult a doctor for a proper dose.

What if I overdose on Tylenol?

Overdose can result in a person’s life and death. As it’s a pain reliever, it has many issues if you overdose on it. It’s good to consult a doctor immediately.


According to the study, there are no interactions with the medicines if combined. This tends to be safe, but the person might visit a doctor before consuming a medicine. Every drug can be good, but only after a doctor’s prescription.

Can You Take Tylenol And Meloxicam Together?

Can You Take Tylenol And Meloxicam Together?

Tylenol and meloxicam are NSAIDs medication that treats pain and inflammation-related issues. Both Tylenol and meloxicam can be taken together as these drugs do not lead to any drug interactions.

Can Meloxicam be taken with Tylenol?

Meloxicam and Aleve (naproxen) are both nonsteroidal anti-inflammatory medications (NSAIDs) that are used to treat pain, fever, and inflammation. They’re used to relieve mild to severe Pain from things like headaches, menstruation, migraines, arthritis, sprains and strains, and toothaches.

For moderate discomfort that is not controlled by NSAIDs alone, NSAIDs can be used with Tylenol (acetaminophen). It’s advised to avoid taking more than one NSAID at a time because you’ll increase your chances of suffering negative effects. Both Tylenol and meloxicam being NSAIDs can lead to some harmful effects. 

GI distress such as bloating, diarrhea, constipation, irritation of the stomach lining, nausea, and vomiting are the most prevalent side effects. NSAIDs also have an impact on renal function, slowing blood flow through the kidneys. They may induce salt and water retention, resulting in edema and excessive potassium levels. 

Some nonsteroidal anti-inflammatory drugs (NSAIDs) have a significant risk of cardiovascular thrombotic events such a heart attack or stroke. NSAIDs can also cause asthma, headaches, sleeplessness, and hives.

It is safer to take Tylenol with either meloxicam, but meloxicam and Tylenol should not be used together. Consult your doctor if the discomfort persists or worsens.

Study on Tylenol and Meloxicam Together

Research: this study was conducted by aRice University, Houston bU.S. Army Institute of Surgical Research, JBSA – Fort Sam Houston, Texas, USA.

Aim: The effects of acetaminophen and meloxicam on platelet aggregation and coagulation function in human blood samples were studied in this study.

Results: the results detected that Acetaminophen or meloxicam had no effect on PT or any Rotem measures. Platelet aggregation and a PTT were harmed by acetaminophen and meloxicam. Characterizing the effects of acetaminophen and meloxicam on bleeding in vivo requires more research (Martini AK, Rodriguez CM, Cap AP, Martini WZ, Dubick MA).

What is Meloxicam, and How does it Work?

Meloxicam, marketed as Mobic, is a nonsteroidal anti-inflammatory medicine used to treat pain and irritation caused by inflammation and enlargement, and hardness in the joints.

This medication can be either orally or injected into the veins. This medication works by preventing the synthetic Cyclooxygenase protein from doing its job, resulting in pain and edema are caused by prostaglandins (Noble, S. and Balfour, J.A., 1996).

What is Tylenol, and How does it Work?

Tylenol is a pain reliever, a nonsteroidal anti-inflammatory drug used to treat a variety of ailments, including muscular pain, migraine, sore throat, flu, arthritis, and more.

It is an OTC medication, you can also buy Tylenol online from certified online pharmacy.

It includes acetaminophen, an active chemical that recognizes the source of the Pain. It produces prostaglandins, which send a message to the brain and prevent Pain (AMEER, B. and GREENBLATT, D.J., 1977).

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Forms and Strengths of Meloxicam 

Form: This medication’s dose can come in the form of capsules, pills, or an injection

Strength: Suppository; 120 mg, 125 mg, 325 mg, 650 mg; Chewable tablets; 80 mg; Junior tablets: 160 mg; Regular strength: 325 mg; Extra strength: 500 mg (Noble, S. and Balfour, J.A., 1996).

Form and Strength of Tylenol

Form: This drug is available in tablet, caplet, capsule, and other forms and is suitable for adults and children.

Strength: Tablets 325mg, 500mg; Caplets containing 325 mg and 500 mg; Capsules 325 mg 500 mg 650 mg (AMEER, B. and GREENBLATT, D.J., 1977).

How to take Meloxicam? 

However, one can consume meloxicam with or without food under the doctor’s guidance and surveillance. It is advised to take meloxicam at the same time every day (Noble, S. and Balfour, J.A., 1996).

How to take Tylenol? 

When symptoms remain, take 2 caplets every 6 hours. If not advised by a doctor, do not take more than 6 caplets in 24 hours. Unless instructed by a doctor, do not take for longer than 10 days (AMEER, B. and GREENBLATT, D.J., 1977).

Meloxicam Dosage                

The drug’s dose for children must be discussed with a doctor since safety is paramount. Adults, on the other hand, should take their medications as follows:

In General Dosage

The recommended dosage for this drug is 15mg, which can be raised to 25mg with a doctor’s approval.

  • In the case of hemodialysis

In the condition of hemodialysis, the dose is around 7.5mg.

  • In the case of adults with osteoarthritis

If diagnosed with osteoarthritis, the oral dose is around 7.5mg.

  • When it comes to rheumatoid arthritis

The recommended dose is 7.5mg.

Meloxicam medicine must be used exactly as recommended because an overdose of this drug can be fatal (Noble, S. and Balfour, J.A., 1996).

Tylenol Dosage 

Dosage in Tablets: This medication’s recommended dosage ranges from 325mg to 500mg when taken orally.

Dosage in Caplets: This medication’s recommended dosage ranges from 325mg to 600mg when taken orally.

Dosage in the Form of Capsule: Tylenol may be taken orally in doses ranging from 325mg to 500mg, much like tablets (AMEER, B. and GREENBLATT, D.J., 1977).

Meloxicam Overdose

Overdosage on this medication can be lethal and can lead to side effects such as drowsiness, dizziness, fatigue. Other than that can also be adverse, including gastrointestinal bleeding, renal failure, coma, which is considered to be a rare case (Noble, S. and Balfour, J.A., 1996).

Tylenol Overdose

Tylenol overdosage can be harmful. According to the US Food and Drug Administration (FDA), taking too much acetaminophen can harm your liver and lead to loss of appetite, nausea, vomiting, and loss of breath (AMEER, B. and GREENBLATT, D.J., 1977).

Side Effects of Meloxicam 

The side effects that occur may be common but, in rare cases, can be adverse. The symptoms are as follows:

Common Side Effects ​

The common symptoms that may occur are: 

  • Fatigue 
  • Diarrhea
  • Abdominal Pain 
  • Nausea

These are the side effects one may or may not experience.

Adverse effects

These symptoms are rare but can lead to severe effects. The symptoms areas 


  • Heart attack 
  • Stroke 
  • Epilepsy
  • Liver damage 
  • Increased blood pressure

Side effects of Tylenol 

The side effects can be standard or can even be adverse. The common symptoms can be as follow: 

Common symptoms             

  • Loss of appetite 
  • Vomiting or nausea 
  • Rashes

Adverse symptoms  

Adverse side effects can be a rare situation; however, in any case, consult the doctor. 

Who cannot take Meloxicam? 

  • Suffer from Difficulty in breathing 
  • Fever or any flu 
  • Skin blisters 
  • Swelling in any part of the body
  • Hives 
  • This medication can be considered as a high-risk drug as it can increase the potential of heart attacks, strokes, etc., and can be deadly if one is suffering from a heart-related issue.
  • It can be dangerous for persons who have certain cardiac or renal illnesses or drinking problems.

Who cannot take Tylenol? 

  • Liver problems: Do not take this medication if you have liver problems
  • Alcohol consumption: Do not use# this medication with alcohol or if you consume alcohol regularly.
  • Children under the age of two: If you are under the age of two, you should not take this medication.
  • Pregnancy: If you’re expecting a child, talk to your doctor before using this drug.
  • Do not take any acetaminophen-containing medicine since it can lead to overdosing.
Can You Take Tylenol With Celebrex?

Can You Take Tylenol With Celebrex?

Tylenol is a medication used for the treatment of pain. Acetaminophen is the generic name of Tylenol. It is a member of the drug class called Analgesics. It works against the pain caused due to cold and fever, headaches, and menstrual cramps.

Tylenol and Celebrex are both medications used to treat pain caused due to various reasons in the body. There are no significant drug interactions observed between these two medications. One can take Tylenol with Celebrex to treat pain after consulting the medical practitioner. (Gunasingha, R.M., Niloy, I.L., Wetstein, B.B., Learn, P.A. and Turza, L.C., 2021)

tylenol with celebrex

Study Of Effectiveness Of Taking Tylenol With Celebrex

A study was conducted by Tijani Issioui et al. to compare the individual efficacy of Tylenol and Celebrex and take it together against pain after surgery.

The total number of participants was 112, and the study was divided into 4 groups:

  • Group 1. Placebo (500 mg)
  • Group 2. Tylenol (2000 mg)
  • Group 3. Celebrex (200 mg)
  • Group 4. Tylenol and Celebrex (2000 mg and 200 mg respectively).

It was observed that Group 4 was more effective in reducing the pain compared to the other groups. Taking Tylenol with Celebrex was observed more effective in reducing the pain after the surgery.

It can be observed that Tylenol can be taken with Celebrex and get effective results.

How It Works


Tylenol blocks the prostaglandin-producing enzymes. Prostaglandin is the chemical that gives the feeling and sensation of pain in the body. The level of prostaglandin decreases due to the blocking of enzymes. It helps to reduce the pain. 


Celebrex blocks COX-2 enzymes and relieves pain. COX-2 enzymes produce prostaglandins that cause pain and inflammation in the body. This helps to decrease the level of prostaglandin and provides relief from pain and inflammation.

Celebrex is a medicine that requires prescription so before consuming these medications consult a doctor and you can buy Celebrex online from a certified online pharmacy. (Chiang, P.C., Ran, Y., Chou, K.J., Cui, Y., Sambrone, A., Chan, C. and Hart, R., 2012)

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Forms And Strengths


Tylenol is available as tablets, capsules, caplets, chewable tablets, and liquid forms.

Capsule: 325 mg, 500 mg

Tablet: 325 mg, 500 mg

Chewable tablet: 80 mg

Liquid solution : 160 mg/5 ml

Caplet extended release: 650 mg

Tablet oral-disintegrating: 80 mg, 160 mg

Caplet 325 mg, 500 mg, 650 mg


Celebrex is an oral medication available as capsules. It comes in the strengths of 50,100,200 and 400 mg capsules.

How To Take


Tylenol can be taken with water before or after a meal. Do not crush or break the tablets. For oral Tylenol, one should use a proper measuring spoon.

It should be taken only as directed and not change the dose without consulting the doctor. Take medical help if you face a problem while taking medicine.


Celebrex can be taken with or without eating food. If you face the problem of stomach upset, it is better to take it with food. It should be taken only as per the directions of a medical practitioner. This medication can be taken at any time, but one should take it regularly.



The normal adult dose of Tylenol extended-release is 1300 mg every 8 hours.

The maximum daily dose should not be more than 3900 mg.

Regular tablets dose is 325-650 mg taken 4 hours daily.

The maximum dose is 3250-4000 mg daily.


The initial adult daily dose is 200 mg, taken twice daily.

The maximum daily dose is 400 mg twice daily.

Who Should Not Take It?


One should not take Tylenol if:

  1. Cirrhosis
  2. Diabetes
  3. Allergic to acetaminophen
  4. Addicted to alcohol

It can be taken by pregnant and breastfeeding women only if prescribed by the doctor in an emergency and necessary conditions.


One should not take Celebrex if:

  1. Allergic to Celecoxib
  2. Asthma
  3. Heart diseases like stroke and high blood pressure
  4. Liver and kidney problems
  5. Bleeding and stomach ulcers
  6. Allergic to NSAIDs

It can be taken by pregnant and breastfeeding women only if prescribed by the doctor in an emergency and necessary conditions.

Side Effects


Following are some common side effects of Tylenol:

  1. Nausea- make you feel uneasy
  2. Stomach pain- discomfort in the abdomen.
  3. Headaches- severe headache leading to disturbance in sleep.
  4. Constipation- leading to digestion problems
  5. Loss of appetite- may lead to weakness

These are severe side effects associated with the medication of Tylenol:

  1. Jaundice- pale yellow urine and weakness
  2. Swelling – complicating some muscle movements
  3. Difficulty in breathing- suffocation, and restlessness
  4. Redness of the skin- constant feeling of itching


Following are some common side effects of Celebrex:

  1. Dizziness- feeling sleepy most of the time
  2. Nausea- feeling like vomiting.
  3. Heartburn- pain in the chest after eating.
  4. Stuffy nose- runny nose and cough problems.
  5. Stomach pain- unable to eat as discomfort in the abdomen.
  6. Constipation- problem in stools.

These are some adverse side effects after using Celebrex:

  1. Signs of heart attack- chest pain, sweating.
  2. Difficulty in breathing- restlessness, suffocation.
  3. Stomach bleeding- vomiting blood, blood in urine and stools.
  4. Anaemia- cold hands, pale skin, weakness.
  5. Swelling- restricting muscle movements.

Take immediate medical help if you face these side effects to prevent further risks.

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Other Precautions While Taking These Medications

  1. Drinking alcohol can lead to more dizziness and bleeding problems. Thus, it is advised not to consume alcohol.
  2. Other medicines for pain and fever can interact and have a negative impact on health. Therefore, do not consume or ask your medical health practitioner before taking such medicines.
  3. Do consult your doctor before taking Tylenol with Celebrex, as it might affect your health and lead to severe side effects.


Tylenol and Celebrex are medications for pain and fever. It is observed that Tylenol can be taken with Celebrex as no major drug interaction was observed between them. Take precautionary medical help before taking it.

Tylenol vs Ibuprofen

Tylenol vs Ibuprofen

What Is Tylenol?

Tylenol is a drug used for various pains in the body as the Medication involves different cures for other body pains and fever. It is a class of Analgesics.

The generic name for Tylenol is acetaminophen. It is one of the pain relievers seen in today’s world—this Medication, primarily known in the USA.

It is an over the counter medication you can also buy Tylenol online from certified pharmacy.

What Is Ibuprofen?

Ibuprofen is an anti-inflammatory drug (NSAIDs) that belongs to the class of nonsteroidal.

It reduces different hormones that cause pain and inflammation in the body. It helps in curing various aches and pains in the body.

It is also an OTC medication, you can also buy Ibuprofen online from certified pharmacy.

conversation of two people on tylenol and ibuprofen

How Does Tylenol Work?

Tylenol is an analgesic and even antipyretic. Tylenol works by obstructing the brain from emitting bodily substances which take out pains in the body. It cures the mild pains in the body. This works as a tool to obstruct pains, aches in the body. (Waldstein, A., 2006)

How Does Ibuprofen Work?

Ibuprofen works by obstructing the production of cyclooxygenase from the body. It helps in reducing pains, swelling, and inflammation. It has a more significant response to injuries and illness. (Xaudiera, S. and Cardenal, A.S., 2020)

Forms And Strengths Of Tylenol



1- Tablet form

325mg, 500mg, 625mg

2- Liquid gel


Forms And Strengths Of Ibuprofen.



1- Tablet

100mg, 200mg, 400mg, 600mg, 800mg

2- Liquid

100mg per 5ml, 50mg per 1.5ml  (infants)

3- Capsule


4- Chewable tablet


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How Should You Take Tylenol?

A person should consume Tylenol as per the instructions printed on the label or the doctor’s suggestion. Tylenol can be consumed after and before food intake with enough water intake before having it.

How Should You Take Ibuprofen?

Ibuprofen is a medicine that should be taken after food intake.

Always follow the instructions given on the label and the doctor’s recommendation.

Syrup form– You should shake the bottle for 10 seconds.

Tablet form– It should be swallowed with water as prescribed by the doctor.

Dosage Of Tylenol


The person can consume two tablets of 500mg in 4 to 6 hours in one dose (If required)

Single-dose can be more than 1000mg

The maximum dose for a day can be taken of 4000mg

A person should consult a doctor before consuming it (Only ten days advisable)


Dosage of Tylenol 325-650mg can be consumed in 1 dose every 4-6 hours

It should not exceed more than five doses a day (3250mg)

Different people can be given extra doses according to their weight and age.

Dosage Of Ibuprofen


A person can consume 800 mg per dose, extending to 3200mg per day.

(Overall 4 doses per day is recommendable)


Children’s doses differ in their age and weight.

For the exact dose, they should consult a doctor.

Who Should Not Take Tylenol?

  • The person who intakes alcohol three times a day
  • If the person has severe liver issues
  • If the person is pregnant (advisable after doctors recommendation)
  • If the person gives breastfeeding to a child, it’s not recommendable because it gets mixed into the milk, which can be harmful.
  • If the person is younger than two years.
  • Undernutrition person
  • Kidney failure
  • Allergic to acetaminophen.

Who Should Not Take Ibuprofen?

Ibuprofen should not be taken by following conditions:

  • A person suffering from allergic issues
  • Who gets asthma attacks
  • Pregnant ladies (unless recommended by a doctor)
  • Children younger than six years old
  • If the person has skin reactions
  • Running nose

Side Effects Of Tylenol

There are no side effects that affect it but contact the doctor if you feel this. If you have unusual effects on your body:

  • Allergic Reaction on the body
  • Rashes on the body
  • Itching
  • Swelling of the tongue, face, throats
  • Sleepy
  • A problem in breathing normally
  • Urine (Dark)
  • Skin becoming yellow.
  • Severe Effects may include
  • Bleeding in intestine
  • Kidney damage
  • Reduce blood count
  • Constipation

Side Effects Of Ibuprofen

Ibuprofen side effects on the body

  • Stomach ache
  • Gastric issues
  • Constipation
  • Heartburn
  • Weight gain
  • Swelling, rashes
  • Liver problem
  • Kidney issues
  • Reducing blood cells

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Drug Interaction With Tylenol

  • Similar drugs are related to acetaminophen.
  • Anesthetics
  • Antibiotics
  • Nicotine
  • Alcohol
  • Anticonvulsants
  • Other fever-related medicines.

Before consuming this drug, Inform the doctor to understand the cause better.

Drug Interaction With Ibuprofen

These are the everyday drug interactions that can be seen

  • Cyclosporine
  • Lithium
  • Methotrexate
  • Blood thinner
  • Blood pressure including water pill
  • Steroids medicine


A study was conducted by S A Cooper et al. to observe the relief of pains in the body.


To observe the random trial between Ibuprofen and acetaminophen (Tylenol) on the Reaction to the pain.


This study was conducted for 6 hours, including 184 members in the panel. Those 184 members were patients who had undergone dental surgery. This study included Ibuprofen 400mg and Tylenol 1000mg.; it was studied to know which Medication would be useful for the pain to get cured in the safest way possible. They observed at regular intervals of 6 hours.


184 were the people with the exact dosage given (given as above). The results surprised the researchers with having Ibuprofen being the most curable one compared to Tylenol. There were side effects on a few patients, but more effective with the Ibuprofen drug. Ibuprofen was safer in comparison with Tylenol in terms of pain.


Both medications have their ways of treating different issues (pains). According to the study, Ibuprofen is a medication that acts more useful for people compared to Tylenol.

Can Tylenol Cause Constipation?

Can Tylenol Cause Constipation?

Tylenol is a drug used to treat pain and fever. It helps to relieve pain caused due to fever, cold, headaches, and menstrual cramps. It also works to reduce fever. Acetaminophen is the generic name, and it belongs to the drug class named Analgesics. It is also called Opioid induced constipation (opioid is a drug class for medications relieving pain).

Through it is an over the counter medication you can even buy Tylenol online from certified pharmacy it is recommended to have doctor’s advise first.

During the medication of Tylenol, there are some side effects associated with it that one might have to face. One of the side effects which one may experience while taking Tylenol is constipation. Around 40 to 60 percent of Tylenol users faces the problem of constipation.

Constipation can be identified from symptoms like hard stools, pain in intestines, longer duration of excretion, dry stools.

How Does Tylenol Cause Constipation?

Tylenol is a pain reliever medicine. Tylenol leads to constipation as it affects bowel movement. It slows down the stool to pass through the intestines.

This makes the bowel absorb more water from the stool as the stool remains for a long time in the bowel. This might keep the stool hard and dry, which makes it difficult to pass and leads to constipation.

In medicinal terms Acetaminophen is the active ingredient which provokes the process of constipation, as it is also included in side effects of it.

(Moir, M.S., Bair, E., Shinnick, P. and Messner, A., 2000)

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Study: Tylenol And Constipation

Research and analysis were conducted by eHealthMe to study the effect of constipation during the medication of Tylenol.

eHealth studied the total individuals taking Tylenol and observed that 165623 people taking Tylenol faced side effects after medication. 2.97% of people (4925) suffered from constipation from these people

Along with this study, another study was conducted where 54 people who faced constipation due to medication of Tylenol were observed.

The severity of constipation was moderate to normal for the majority of the people and mainly affected the women participants.

Thus, it can be concluded that Tylenol causes constipation. Everyone might not face the effect, but it does affect some people. (Dowdell, T.D., Govindaraj, S. and Jain, P.C., 1992)

How Does Tylenol Work?

Tylenol works by blocking the enzymes which produce prostaglandins. Prostaglandin is the chemical that makes the body feel pain. Thus, as Tylenol blocks, the enzymes, the level of prostaglandin decreases and also reduces the feeling of pain.

Forms And Strengths

Tylenol is an oral medication available in different forms such as tablets, capsules, caplets, chewable tablets, liquid solution, extended-release caplets, and orally disintegrating tablets.




325 mg, 500 mg


325 mg, 500 mg

Tablet oral-disintegrating

80 mg, 160 mg


325 mg, 500 mg, 650 mg

Caplet extended release

650 mg

Chewable tablet

80 mg

Liquid solution

160 mg/5 ml

How To Take Tylenol?

One should take Tylenol only as per the direction of the medical expert. It should be taken with water before or after eating food. Do not break or crush the tablets. A proper measuring spoon should be used for oral Tylenol.

Do not try to increase or decrease the dose without consulting the doctor. Do consult before stopping the medicine. If you face any problems while taking medicine, contact your doctor immediately.

Doctors sometimes prescribes Tylenol with codeine according to your health status, as codeine is opioid it slows down central nervous system indirectly effecting digesting functions also, so always prefer doctor’s advice regarding prescribed medicine.


Adult Dose:

2 tablets of 500 mg are taken every 4-6 hours in one dose.

Single-dose should be more than 1000 mg.

The maximum daily dose is 4000 mg.

It is advised not to take it for more than 10 days.

Pediatric dose (6-12):

1 dose should be 325-650 mg given every 4-6 hours.

The maximum dose should not be more than 5 doses, i.e., 3250 mg

The dose can be changed depending upon the age and weight of an individual.

Who Should Not Take It?

One should not take Tylenol if:

  1. Allergic to acetaminophen
  2. Serious liver disease like Cirrhosis
  3. Regular consumption of alcohol
  4. Diabetes

Pregnant and breastfeeding women can take this only if prescribed by the doctor in an emergency and necessary conditions.

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Side Effects

These are some common side effects of taking Tylenol:

  1. Nausea
  2. Loss of appetite
  3. Constipation
  4. Headaches
  5. Stomach pain

Following are some severe side effects which one may face after taking Tylenol:

  1. Difficulty in breathing
  2. Redness of the skin
  3. Swelling
  4. Abdomen pain
  5. Jaundice
  6. Itching and rashes on the skin

One should immediately consult the medical practitioner if any of these side effects are observed. The doctor may change the dose or terminate the medication depending upon the situation.

Drug Interactions

Tylenol may interact with the following drugs:

  1. Other medicines containing acetaminophen
  2. Antibiotics
  3. Anaesthetics
  4. Anticonvulsants
  5. Alcohol
  6. Nicotine
  7. Other fever medications

Inform your doctor if you take any of these medications, as these interactions can severely affect the body.

How To Tackle Constipation From Tylenol?

The problem of constipation caused due to Tylenol can be tackled by taking laxatives. These laxatives help to move your stool move in the bowel and allow the liquid to stay in the bowel.

Sennosides and PEG are some of the laxatives which can be used to treat the problem of constipation. In addition to this physical exercise, high fibre diet, and staying hydrated are also some of the measures to tackle constipation.

Do consult your doctor to know about the effects of these medicines on your body before taking them.


Tylenol is a widely used muscle relaxant that helps to tackle pain and ache. Tylenol works on central nervous system and indirectly effects on involuntary actions in digestion system leading to constipation.

Tylenol may lead to constipation in some individuals. This problem can be solved by following a proper diet and exercise. If you experience such an effect, inform your doctor and get the necessary professional help.

Can You Take Gabapentin And Tylenol Together?

Can You Take Gabapentin And Tylenol Together?

If you have epilepsy, chances are that you are on Gabapentin. Add fever to this and most likely you will be considering consuming Tylenol to take care of that. So the obvious question that will hot your mind will be can you take Gabapentin and Tylenol together?

Gabapentin is an anticonvulsant and anti-epileptic medication. It affects the chemicals and neurons that produce seizures and some forms of pain. Gabapentin is a prescribed medication available under the brand name Neurontin. It is mainly used to treat partial seizure that occur because of epilepsy.

Gabapentin is widely used in US. Its consumption has seen a drastic rise over the last decade. In the year 2004, the total sale was 18 million, this shot up to 47 million in the year 2019.

Tylenol, also known as acetaminophen, is a pain reliever and fever reducer. Colds, flu, headaches, muscular pains, arthritis, menstrual cramps, and fevers are all treated with this remedy. It also helps to reduce body temperature and ease minor pain.  

It is an OTC medication, you can buy Tylenol online from certified pharmacy.Tylenol is brand name which belongs to drug class of Analgesic or Opioid. Tylenol is an OTC medication.

The total sale of Tylenol was 6 million in the year 2004. Contrary to Gabapentin, the sales of Tylenol has dropped substantially over the last decade with sales going down to as less as 4.5 million in the year 2019.

The common thing about these two medicines is that they can treat pain, but their work is quite different.

Taking Gabapentin and Tylenol together

You can take Gabapentin and Tylenol together if your doctor prescribes it. Gabapentin is commonly used with OTC medications for pain relief and is usually safe to take.

We suggest you to be cautious when taking Gabapentin and other OTC medicines together, as they might increase Gabapentin’s side effects, such as nausea or dizziness. 

Please consult your doctor for any detected symptoms of the side effects or health issues occurring after taking them. 

How does both the Medications work?

Gabapentin appears to work by affecting the activity of molecules called neurotransmitters, which convey information between nerve cells and modify electrical activity in the brain. Gabapentin relieves pain by changing the way the body senses pain. These medication is also used as to treat nerve pain.

Tylenol reduces pain by raising the pain threshold, which means that a person must experience more pain before feeling it. When used together, both these drugs can reduce pain and amplify side effects in some people.

A study published in the Journal of Anaesthesiology Clinical Pharmacology observed the use of Gabapentin, Tylenol, and a combination of Gabapentin and Tylenol together as a protective premedication for post-operative analgesia.

It was a randomized, double-blind study conducted on 120 consenting patients. The drugs were given 2 hours before the induction. Time, number, VAS score at rest, and side effects were noted.

The study stated that premedication with antihyperalgesic and analgesic medications could help reduce postoperative pain.

Gabapentin premedication is successful in delivering superior postoperative pain management with fewer and later rescue analgesics, but it induces more nausea and vomiting episodes as well as greater degrees of drowsiness (study of acetaminophen, gabapentin and combination of acetaminophen with gabapentin for post-operative analgesia).

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A study published in the Journal of Anaesthesiology Clinical Pharmacology observed the use of Gabapentin, Tylenol, and a combination of Gabapentin and Tylenol together as a protective premedication for post-operative analgesia.

It was a randomized, double-blind study conducted on 120 consenting patients. The drugs were given 2 hours before the induction. Time, number, VAS score at rest, and side effects were noted.

The study stated that premedication with antihyperalgesic and analgesic medications could help reduce postoperative pain. Gabapentin premedication is successful in delivering superior postoperative pain management with fewer and later rescue analgesics, but it induces more nausea and vomiting episodes as well as greater degrees of drowsiness. (Syal, K., Goma, M., Dogra, R. K., Ohri, A., Gupta, A. K., & Goel, A. (2010).)

Forms and Strength of tylenol and Gabpentin

Gabapentin comes in capsules, tablets, and liquid forms. 


Capsules: 100, 300 and 400 mg.

Tablets: 600 and 800 mg.

Liquid: 250 mg per 5 mL.

Tylenol comes in capsules, tablets, and liquid forms.


Capsules: 325 mg and 500 mg.

Tablets: 325 and 500 mg.

Liquid: 160 and 500 mg per 5 mL.

How to Administer Gabapentin and Tylenol together?

Gabapentin pills, tablets, and oral solutions are commonly given three times a day, with or without meals.

Gabapentin can be started as a single 300 mg dosage on Day 1, 600 mg twice a day on Day 2, and 900 mg twice a day on Day 3 in individuals with postherpetic neuralgia (300 mg three times a day).

After then, the dose can be titrated up to 1800 mg per day as needed for pain management (600 mg three times a day) (Goa, K.L. and Sorkin, E.M., 1993. Gabapentin).

Tylenol is also available in the form of tablets or an oral solution. It can also be taken with or without meals. Tylenol Regular Strength is usually taken in two 650 mg pills or capsules every four to six hours.

In a 24-hour period, adults and adolescents aged 12 and above should not consume more than 10 Tylenol tablets (3,250 mg). Use for a maximum of 10 days.

Regular strength Tylenol can be taken by children aged 6 to 11. (325 mg). Children under the age of six should only be given Tylenol under the supervision of a doctor or other healthcare professional.

The recommended dose of Tylenol for young children is decided by the child’s weight and age (Sahajwalla, C.G. and Ayres, J.W., 1991).

If you have a sensitive stomach, we would suggest you eat food before taking these medicines as it may lessen the effects of an upset stomach. 

As mentioned above in the article published by the Journal of Anaesthesiology Clinical Pharmacology, the study studied the effects of Acetaminophen 1000 mg and 1200 mg of Gabapentin when taken together.

Can You Take Gabapentin And Tylenol Together

Who cannot take Gabapentin or Tylenol?

Gabapentin can cause life-threatening breathing issues, especially if you already have a respiratory disease or are taking other medications that make you sleepy or slow your breathing. If your breathing is sluggish, get medical help right once.

While using Gabapentin, some patients have suicidal ideation or behavioral problems. Keep an eye on your mood and symptoms for any changes. Notify your doctor if you develop new or worsening symptoms.

If you have severe liver disease, you should avoid using Tylenol. An acetaminophen overdose can harm your liver or perhaps cause death. Adults and teens weighing at least 110 pounds should not consume more than 1000 mg at a time or 4000 mg in 24 hours.

Children under the age of 12 should not take more than five doses in 24 hours and should only take the quantity of mg per dosage suggested for their weight and age. Strictly follow the directions on the label.

We strongly suggest you not to drink alcohol, use heavy machinery or drive when under the influence of either of these two medicines. 

Side Effects

Side Effects

Some side effects of these medications are:


  • Weak or shallow breathing
  • Blue colored skin
  • Confusion
  • Increased seizures
  • Fever
  • Headache
  • Nausea and vomiting
  • Fatigue
  • Dizziness
  • Instability in body movements
  • Unusual eye movements
  • Blurred vision

Some side effects of these medications are:


  • Stomach pain
  • Loss of appetite
  • Tiredness
  • Jaundice
  • Dark urine
  • Itching
  • Rashes
  • Dark urine
  • Clay-coloured stools
  • Jaundice

Other side effects can happen when taking Gabapentin and Tylenol, which are not mentioned in this article. Consult your doctor as soon as you have any symptoms of one. 

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Interractions Of Gabapentin and Tylenol With Other Drugs

Gabapentin is known to interact with:

  • Aspirin
  • Flexeril
  • Lexapro
  • Tylenol
  • Vitamins

Gabapentin interacts with 262 known medications.

Tylenol is known to interact with:

  • Aspirin
  • Gabapentin
  • Ibuprofen
  • Metformin
  • Omeprazole

Tylenol interacts with 105 known medications.

These medications are known to interact with alcohol, vitamin, and herbal drugs.  


We can take Gabapentin and Tylenol together for pain relief under proper guidance. As per most studies it is perfectly safe it is perfectly safe to take Gabapentin and Tylenol together. Both the medications have different effects on your body.

Although, some people may face severe side effects and show quick results. We suggest you take caution while consuming the medication and talk to your doctor if any side effects occur. 

Tylenol vs Paracetamol

Tylenol vs Paracetamol

What is Tylenol? 

Acetaminophen is marketed under the brand name Tylenol. Tylenol is a pain reliever and fever reducer as well. Colds and flu, headaches, muscle pains, arthritis, menstrual cramps, and fevers are treated with Tylenol to decrease fever and relieve moderate pain (Douglas, D.R., Sholal, J.B. and Smilkstein, M.J., 1996).

What is Paracetamol?

Paracetamol is also another name for acetaminophen. It is a mild pain medication with few adverse effects. Sciatica, Muscle Pain, Fever, and Pain are among the conditions for this medication (Prescott, L.F., 2000).

two people conversation on tylenol comparing with paracetamol

Forms and Strengths


Tylenol adult acetaminophen medications come in three strengths:

  • regular strength (325 mg)
  • extra strength (500 mg)
  • extended-release Tylenol 8 HR (625 mg)

Tablets (325 mg) and liquid gel capsules are both available in Tylenol Regular Strength (325 mg)


The following forms and strengths of paracetamol are available:

  • Tablets: 325mg – 500mg
  • Extended-release caplets: 650mg
  • Capsules: 500mg
  • Gel caps / gel tabs: 500mg
  • Oral suspension or solution: 160mg or 5ml
  • Liquid (oral): 500mg or 5ml
  • Oral-disintegrating tablets: 80mg – 160mg
  • Caplets: 325mg, 500mg and 650mg
  • Syrup: 160mg or 5ml
  • Suppositories: 125mg, 250mg and 500mg

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For Tylenol

The typical dose of Tylenol Regular Strength is two tablets or capsules of 650 mg every four to six hours.

Adults and adolescents aged 12 and above should not take more than 10 Tylenol pills (3,250 mg) in 24 hours. Use for no more than ten days.

Children between 6 and 11 can take regular strength Tylenol (325 mg). Tylenol should only be given to children under the age of six under the supervision of a doctor or other healthcare expert. 

When providing Tylenol to young children, the appropriate dose is determined by the child’s weight and age (Lesko, S.M. and Mitchell, A.A., 1999).

For Paracetamol

Adults and children aged 16 and above should take 500 mg to 1 g every 4-6 hours, up to a maximum of 4 g per day.

The standard dose for children aged 12-15 years is 480-750 mg every 4-6 hours, up to a maximum of four doses per day.

If needed, a dosage of paracetamol can be taken every 4-6 hours, up to four times each day. Remember that you should wait at least four hours between doses and that you should not take more than four paracetamol doses in 24 hours (Cranswick, N. and Coghlan, D., 2000).

Are Tylenol and Paracetamol the same thing?

In the United States, paracetamol is known as acetaminophen. It comes in a variety of brands, including Tylenol, Mapap, and Panadol, as well as generics and store-specific brands.

Although suggested doses and available strengths may vary significantly between nations, there are no changes in the chemical structure or therapeutic usage of Tylenol and paracetamol.

Tylenol is commonly referred as to as paracetamol in various parts of the world, including Europe, Australia, India, and New Zealand.

Side Effects

Tyleno Side Effects

Although acetaminophen has negative effects, most people do not notice them. The majority of people well tolerate this medicine. It has caused allergic reactions in a few persons. Severe liver damage is the most concerning adverse effect. 

Acetaminophen has the following common side effects:

  • Loss of appetite
  • Itching
  • Rash
  • Headache
  • Dark urine
  • Clay-colored feces
Paracetamol Side Effects

Some people have suffered adverse reactions to acetaminophen in very uncommon situations. Contact your healthcare professional right away if you have any of the following symptoms after taking acetaminophen.

  • Skin itching
  • Peeling of skin
  • Difficulty breathing
  • Swelling of your face, lips, throat, or tongue
  • Skin blistering 
  • severe dizziness

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How does it work?

Acetaminophen belongs to the analgesics (pain relievers) and antipyretics pharmacological classes (fever reducers). Acetaminophen’s specific method of action is unknown. 

Prostaglandin production in the brain may be reduced by this medication. Prostaglandins are inflammatory and swelling-causing substances. Acetaminophen alleviates pain by raising the pain threshold, which means that a person must experience more pain before feeling it. 

It works by reducing fever by affecting the brain’s heat-regulating region. When the body’s temperature rises, it instructs the center to lower the body’s temperature (Graham, G.G. and Scott, K.F., 2005. Mechanism of action of paracetamol)

Tylenol vs Toradol: Which is Effective?

Tylenol vs Toradol: Which is Effective?

What is Tylenol?

Tylenol is a medication that belongs to the Analgesics drug class, Tylenol is used for migraines, muscle aches, toothache, and various types of body pains used for medication as a pain reliever, and fever reducer. Tylenol works by affecting the production of chemicals that cause pain and swelling inside the body. Tylenol is available over the counter, you can buy Tylenol online from a certified online pharmacy. (Mitchell, M.L., 1989).

What Is Toradol?

Ketorolac is a non-steroidal anti-inflammatory sold under the brand name Toradol that treats pain and inflammation. As the medication only treats mild pain, it cannot treat severe pain caused by arthritis. This medication precisely works by blocking the naturally occurring chemical substances that cause pain and inflammation(Felsen, D., 1993).

conversation on tylenol and toradol

Difference: Tylenol vs Toradol

This study was conducted by J Endod

Objective: Comparing Tylenol and Toradol in treating acute apical periodontitis

Method: A total of 66 patients with severe pain were randomly assigned to either Toradol or Tylenol (33 patients in each group) and their pain scores were measured once every 10 minutes for 90 minutes following administration.

Result: The Toradol group experienced considerably less pain than the Tylenol group according to the research.

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Dosage of Tylenol

  • The dosage is determined by the individual’s age and weight. Tylenol comes in a variety of forms, including tablets, chewable tablets, liquid, and powder.
  • Initial dosage: A single dose of 1000 mg Tylenol can be taken by teenagers and adults weighing at least 50 kg (110 pounds).
  • Maximum dosage: Over the course of the day, the total dose should not exceed 4000 mg.



  • Initial dosage: 30mg one dose injectable
  • Maximum dose: 120mg (not advisable to exceed more or can lead to overdose)

Oral Administration

  • Initial Orally – 20 mg at a time
  • The maximum dose: is 40 mg per kilogram of body weight.

Dosage of Toradol

The treatment should not last longer than 5 days.
Injectable dosage:

  • 30 mg intravenous single dose or 60 mg intramuscular single dose
  • The maximum dose should not be more than 120 milligrams.

Oral dosage:

  • After intramuscular or intravenous therapy, take 20 mg once.
  • The maximum daily dose should not exceed 40mg.

Side Effects Of Toradol

Adverse Side Effects

The adverse side effects are as follows:

  • Pessimistic thoughts  
  • Euphoric feeling 
  • Bronchospasm
  • Liver failure
  • Depression
  • Hemolytic-uremic syndrome

Contact the medical expert immediately if notice any of these symptoms. 


Common Side Effects

Common Side Effects

  • Vomiting or nausea 
  • Drowsiness and dizziness 
  • Abdominal pain or stomach pain 
  • Diarrhea or constipation 
  • Itching or irritation

These are a few common side effects that won’t last long but in any case, consult the physician. 

Adverse Side Effects

Adverse Side Effects

While following are some severe side effects that need to be addressed quickly and require emergency doctor help:

  • Difficulty in breathing
  • Swelling of face, throat, or tongue.
  • Upper stomach pain
  • Allergic reaction


Common Side Effects

Following are some common side effects which are associated with the medication of

  • Nausea
  • Rash and itching
  • Loss of appetite

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Tylenol or Toradol: Which Medication Is Effective?

Both the medication treat pain however toradol also treats fever. According to the study Toradol was more effective than Tylenol. Thus, consult the doctor before taking any of the medications and take effective measures. Do not overdose on any of the drugs or can lead to lethal side effects(Petrikovets, A., Sheyn, D., Sun, H.H., Chapman, G.C., Mahajan, S.T., Pollard, R.R., El-Nashar, S.A., Hijaz, A.K. and Mangel, J., 2019).
Can You Take Naproxen and Tylenol?

Can You Take Naproxen and Tylenol?

Naproxen is a non-steroidal anti-inflammatory drug (NSAID). Naproxen is used for the treatment of painful conditions such as arthritis, sprains and strains, backache, menstrual pain, and gout pain. Buy Naproxen online from a certified online pharmacy.

Tylenol is an over-the-counter medicine used to treat reduce symptoms of pain and fever. Tylenol belongs to a class of drugs called Analgesics. Tylenol could be taken by adults and children above the age of 12.   

Can Naproxen And Tylenol Be Taken Together?

Naproxen and Tylenol could be taken together and found to be safe. However, it is advisable to take both medicines at different times for more effective results.

Staggering the medication can help to extend relief from pain. In case the pain is severe Tylenol alone may not be effective.

Doses of Naproxen could be added. A combination of both the medicine may work better than either drug alone.(Akhter, T., BAQAI, R. and Aziz, M., 2010)

conversation of two people on naproxen and tylenol

Difference Between Naproxen And Tylenol

                                                  Naproxen                                                    Tylenol

Naproxen works well for treating mild to moderate pain or inflammation.

Tylenol effectively reduces fever and relieves pain, but it doesn’t lower inflammation and swelling.

Naproxen is good for relieving pain from common conditions like menstrual cramps, toothaches, and arthritis.

Works well to relieve pain and fevers. Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.

Naproxen causes fewer stomach problems and is generally safe to use. Naproxen is not safe for pregnant women and people who are above the age of 60. Could cause kidney problems and stomach bleeding if taken for a longer period.

Tylenol causes less upset stomach, ulcers, bruising, and bleeding than other pain medications. It doesn’t cause kidney damage and is also safe to use for people suffering from heart problems or in case of pregnancy.

Naproxen can raise the risk of getting blood clots, heart attack, or stroke.

Drinking alcohol while taking Tylenol can damage the liver

Comparison of Side Effects of Naproxen And Tylenol

The utility of Tylenol and Naproxen are largely defined by their side effects. The side effects of Tylenol are minor and may include stomach upset, nausea, loss of appetite, and headache. On occasion, itchiness and rash can also develop. By contrast, Naproxen can cause heartburn, stomach pain, and peptic ulcers. Long-term or excessive use can affect blood pressure and clotting and increase the risk of bleeding, hypertension, peripheral edema (leg swelling), heart attack, and stroke. Tylenol is neither associated with cardiovascular nor peptic ulcer risk. It can, however, cause serious liver damage if used in excess (more than 4,000 milligrams per day) or taken with alcohol. While Naproxen can also hurt the liver if used in excess, the risk is far smaller. The same applies to the kidneys but usually only when there is an underlying kidney disorder.(Leuschen, M.P., Filipi, M. and Healey, K., 2004)

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Whom Should Avoid Naproxen

Some medicines under certain conditions are not suitable for people and may only be used after taking advice from a doctor or pharmacist. Those conditions may be;
  • If you have asthma or any other allergic disorder.
  • If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohn’s disease or ulcerative colitis.
  • If you have a heart condition or a problem with your blood vessels or circulation.
  • If you have high blood pressure.
  • If you have ever had blood clotting problems.
  • If you have high blood sugar or cholesterol levels.
  • If you are a smoker.
  • If you have a connective tissue disorder, such as systemic lupus erythematosus (an inflammatory condition also called lupus or SLE).
  • If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
  • If you have ever had an allergic reaction to any other NSAID.(Risser, A., Donovan, D., Heintzman, J., and Page, T., 2009)



The recommended dosage of Naproxen, for adults, is one pill every 8–12 hours. However, this depends on the strength of the medication. While, Tylenol generally comes in 325 mg, 500 mg, or 650 mg pills.

  • 1 or 2 325 mg pills every 4–6 hours, taking no more than 8–10 pills per day
  • 1 or 2 500 mg pills every 4–6 hours, taking no more than 6 pills per day
  • 1 or 2 650 mg extended-release pills every 8 hours, taking no more than 4–6 pills per day

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