Can You Take Meloxicam and Lisinopril Together?

Can You Take Meloxicam and Lisinopril Together?

Ever been curious to know about how two medications would work on two different conditions at the same time if taken together? There will be a question: how would Meloxicam and Lisinopril react on your body and should it be taken or not?

You should know about meloxicam and Lisinopril work on what conditions.

Meloxicam is used as a saviour for treating pain like situations, joint stiffness, or swelling on the body. It mainly works as a tool for treating arthritis. Meloxicam belongs to the drug class of Non Steroidal Anti-Inflammatory drug (NSAID).

Meloxicam has various Brand names known as Anjeso, Mobic, Qmiiz OD, Vivlodex.

Some varieties that these brand medicines show up are as follows:

  • In adults Anjeso is used for treating moderate to severe pains.
  • Vivlodex should be used only within adults.
  • Qmiiz OD is used for adults and kids who weigh more than 132 pounds.

Lisinopril is used for conditions such as high blood pressure. It is a boon for many people who tend to face blood pressure issues. It is used between people who are older than 6 years of age. In other ways Lisinopril is used in treating conditions such as congestive heart failure within adults.

Lisinopril is not available over the counter as it is a prescription medicine. you can also buy lisinopril online from a certified online pharmacy but it is recommended to get doctor’s prescription first.

Lisinopril belongs to the drug class ACE Inhibitors. In simple terms ACE (Angiotensin- converting enzyme) drug class consists of medicines that help the veins and arteries to lower the blood pressure. Brand names of Lisinopril are Prinivil, Qbrelis, Zestril. (Lancaster, S.G. and Todd, P.A., 1988.)

How Does Meloxicam And Lisinopril Work on The Body?

As it is one of the strongest painkillers to treat pain. Meloxicam is an Anti-Inflammatory drug that works on the body by blocking prostaglandins which produce inflammation. Once the inflammation is controlled, it reduces the pain and stiffness in the body.

Lisinopril is the most preferred medicine to control high blood pressure situations. Lisinopril works on the body by blocking the production of the chemicals that harden blood vessels. Once the blood vessels are relaxed blood flows smoothly. This smooth flow of blood throughout the body will make your blood pressure in control. (Kumar, B., 2015)

Can You Consume Meloxicam And Lisinopril Together?

You must have got a gist about the two different medications and how it works on the body. Let’s get on to the real question about whether consuming Meloxicam and Lisinopril is a good option to deal with?

Partially you can consume the medication together. This medication may affect your body in a way that it can create kidney issues. This problem may arise when you are consuming the medications too often or on a regular basis.

Consuming both medicines together can create situations like Lisinopril might reduce its working on your body. Lisinopril might stop working to lower the blood pressure. (Kumar, B., 2015)

Precautions Before Consuming Meloxicam And Lisinopril

It is very important for you to keep in mind about the precautions you take before consuming medicines. This will prevent you from not getting affected by the side effects.


  • Do not use the medicine for a longer duration. It may cause you heart attacks.
  • Do not use the medicine if you have faced heart issues.
  • Avoid consuming alcoholic beverages
  • Consume with food intake to avoid stomach aches
  • If you are allergic to Meloxicam or Aspirin. (If you are allergic to Aspirin there is a chance of you being allergic to Meloxicam as well)


  • Do not consume, if you are pregnant.
  • It’s not a good option for you to consume if you have angioedema.
  • Do not think of consuming If you are diabetic.
  • If you have any kidney issues avoid consuming.
  • Do not breastfeed if you are on Lisinopril medication.
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Forms And Dosage


  • Tablet and capsule form: 5mg, 7.5 mg,10 mg, 15 mg, 30 mg/mL


  • Tablet Form: 2.5mg, 5mg, 10mg, 20mg, 30mg, 40mg.
  • Oral solution: 1mg/ml (Qbrelis)

Usual Dosage of Meloxicam

Adult Dose

Dose at start- 7.5mg (once in a day)

Continuity dose- 15mg (Once in a day)

Max dose- 15mg (once in a day)

Usual Dosage of Lisinopril

Dosage for Hypertension (Adult)

Starting Dose: 5mg or 10mg (Once a day)

Continuation Dose: 20 to 40mg (Once a day)

Max Dose: 80mg (Once in a day)


Congestive heart failure dosage (Adults)

Starting dose: 2.5 or 5mg (Once a day)

Continuation dose: Will be decided by the first dose

Max dose: Not more than 40mg in a day

Side effects that you might face after consuming Meloxicam and Lisinopril

As the two medications work for the betterment, it has side effects that will affect your health.

Mentioned below are the symptoms that you might face:

  • Nausea
  • Urinating problems
  • Breathlessness
  • Cramps (Muscles)
  • Dizziness, Drowsiness
  • Heartbeats getting changed
  • Weight loss or gain.
  • Drowsiness

 If you are severely affected by the symptoms then get medical help.


Meloxicam and Lisinopril are saviours for some people. Other people may see the effects of lisinopril not working on their body. As meloxicam is used to treat arthritis and Lisinopril is used in controlling high blood pressure. Consuming Meloxicam and Lisinopril can affect your kidney to function properly.

Some of the Blood pressure medicines and anti-inflammatory drugs affect the health in a severe manner, but consuming Meloxicam and Lisinopril will not have much effect.

There are some of the side effects that you might observe such as weakness, dizziness and a few others. You should consult the doctor before consuming Meloxicam and Lisinopril. Both the medications need a compulsory prescription.

Lisinopril and Alcohol – Can We Take Them Together?

Lisinopril and Alcohol – Can We Take Them Together?

As everyone may know, the use of Lisinopril; if not, you can get information below.

In short, Lisinopril is a high blood pressure medication.

If you consume alcohol and Lisinopril to control your blood pressure.

So many questions may arise regarding a combination of both. The blog may clear all your doubts and may give helpful information.

Know All About Lisinopril

Lisinopril is a generic medication which belongs to the drug class known as Angiotensin Converting Enzyme(ACE) inhibitor.

Lisinopril is sold under various brand names called Prinivil, Zestril and Qbrelis. FDA approved it in 1987 to treat hypertension.

You can purchase Lisinopril online from a certified online pharmacy but it is required to get a doctor’s prescription first?

Lisinopril is used to treat the following conditions-

  • Hypertension(high blood pressure)
  • Heart attack
  • Congestive heart failure
  • Protecting kidneys in a patient with Diabetes
  • Chronic kidney disease
  • Migraines

Lisinopril works by blocking the action of ACE enzymes in the renin-angiotensin system(RAS). This enzyme produces a hormone called angiotensin-II, which helps regulate blood pressure by causing blood vessels to constrict.

Lisinopril prevents angiotensin-I from being converted to angiotensin-II.

By blocking the production of angiotensin-II, Lisinopril keeps blood vessels open and relaxed, lowering blood pressure.

So let’s explore the relationship between Lisinopril and Alcohol.

Can I Drink Alcohol While Consuming Lisinopril?

You can’t drink Alcohol while consuming hypertension medication(Lisinopril). The effect of alcohol depends on the type of drug the patient is taking.

Before taking Lisinopril, consult your healthcare provider about your medical history and discuss whether drinking Alcohol is safe or what amount of alcohol is safe for you.

Light or moderate alcohol use can cause a very slight decrease in blood pressure which may be dangerous if it happens often.

Maximum more than four drinks in one sitting or Excessive alcohol consumption can cause people to neglect personal care and identity. Thus it increases the risk of heart disease and results in high blood pressure.

If you have a habit of drinking Alcohol, then two drinks for men and one drink for women are suggested.

Drinking Alcohol can lead to short-term and long-term effects, increasing the risk of side effects. So people with hypertension are typically advised to cut back the habit of Alcohol or avoid it entirely.

Does Lisinopril Interact With Alcohol?

Yes, Lisinopril does interact with Alcohol. Lisinopril is an ACE inhibitor considered for treating high blood pressure in many people. When Lisinopril and Alcohol are combined, it is a potent interaction which results in dangerous side effects.

The interaction of Lisinopril with Alcohol reduces the drug’s effectiveness.

Studies state that drinking too much alcohol is a common reason for high blood pressure, and it makes the condition worse if we use medication to treat high blood pressure.

When you drink Alcohol and Lisinopril is already in your system, it can lower your blood pressure and lead to experiencing symptoms like dizziness and fainting.

If you notice that Lisinopril makes you dizzy without consuming Alcohol, try to avoid combining it with Alcohol.

Lisinopril and Alcohol can also make blood pressure higher and make the problem of heart failure worse in people who are consuming Lisinopril for such conditions. (Spies, C.D., Sander, M., Stangl, K., Fernandez-Sola, J., Preedy, V.R., Rubin, E., Andreasson, S., Hanna, E.Z. and Kox, W.J., 2001.)

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What is the Connection Between Hypertension and Alcohol?

Regular use of alcohol may lead to addiction and harm to your internal organs. Alcohol acts as a nervous system depressant. There are many disadvantages of consuming Alcohol, and if it is combined with other medication, it undoubtedly impacts our healthy life.

If Alcohol is consumed at a low level, it does not increase blood pressure, but it may lower the blood pressure slightly. Typically more than three drinks can result in higher blood pressure. As many factors work together, the long term effect of Alcohol on Blood pressure may be life-threatening.

What Is Blood Pressure?

Blood pressure is the pressure of pushing blood against the wall of your arteries. The Arteries carry blood from your heart to other parts of your body.

Blood flows at two different pressures-high and low.

Blood pressure higher than usual is termed “High Blood Pressure” or “Hypertension”.High blood pressure occurs when the heart contracts and forces blood through the arteries. High pressure tends to cause the most damage when it is elevated.

It damages the lining of arteries which causes scarring and hardening of arteries and eventually leads to blockage. These blockages can block the blood flow to the heart, brain and other essential organs. Heart attacks are the most common complication caused by hypertension.

People with hypertension often don’t realise they have it, as it does not cause any symptoms until they have complications like a heart attack or stroke. That’s why hypertension is called a “silent killer”.

Low blood pressure seems to occur when the heart is relaxed. Low blood pressure is also termed “Hypotension”.When blood pressure gets low, it is dangerous, which usually occurs due to disease or a large amount of blood loss. The low blood pressure shows symptoms like dizziness and pale skin. Since low blood pressure is not a long-term health problem, high blood pressure creates more complications.

Let’s read below to know how the usage of Alcohol affects the process of blood pressure.

How Does Alcohol Affect Blood pressure?

There are many ways in which Alcohol indirectly affects blood pressure.

  • The nervous system plays an essential role in controlling blood pressure; thus, Alcohol is known to affect the process of the nervous system.
  • Pressure receptors are Baroreceptors. They sense the blood pressure and relay the information to the brain to maintain proper blood pressure. Thus Alcohol affects the changes in pressure receptors by making blood pressure higher.
  • Cortisol is the primary(main) stress hormone that raises blood pressure, and Alcohol increases the amount of Cortisol and thus, blood pressure increases.
  • Alcohol increases the amount of calcium in muscles those line arteries; this can cause arteries to become more constricted, elevating blood pressure.
  • Alcohol interacts with vasoconstrictor hormone to increase blood pressure, causing arteries to constrict and retain fluid filtered in the kidney.
  • People who are overweight are known to increase blood pressure. The empty calories in alcohol lead to weight gain over the long term and further increase blood pressure.

Since there is no single factor that results in higher blood pressure due to the usage of Alcohol, it is a combination of factors that increases blood pressure.

Side Effects and Risks of Combining Lisinopril and Alcohol?

Mixing Lisinopril with Alcohol can lead to

  • Dizziness
  • Lightheadedness
  • Fainting
  • Arrhythmia(irregular heartbeat)
  • Other heart problem

Avoid doing activities like driving a car or operating machinery, which require concentration and coordination while consuming Alcohol.Extreme feeling of dizziness or fainting may increase the risk of falling, which may harm you. Don’t even take a single drink of alcohol without knowing its effect on your body while taking Lisinopril.

Which People Are More At Risk When Combining Alcohol With Lisinopril?

Everyone has an equal chance of risk if they intake both Alcohol and Lisinopril, but we can’t define which group of people have more trouble.

But the National Institute on Alcohol Abuse and Alcoholism states that more risk is reported among such groups of people.

  • Older people above 65 years
  • Women
  • People who take multiple medications

This study was conducted by


Alcohol shows a negative impact on your lifestyle. The interaction of any medication may give a bad result.

Taking Lisinopril and Alcohol together can be a dangerous combination since there is an advanced connection between alcohol and blood pressure which affects essential organs.

The combined intake may show a positive effect on blood pressure by increasing or decreasing it. It may cause common effects like dizziness and fainting and lead to serious effects and worsen the heart problem.

So take advice from health care providers before using Lisinopril to know its benefits and risks and mostly avoid the usage of Lisinopril and alcohol together.

How Long Does Lisinopril Stay In Your System?

How Long Does Lisinopril Stay In Your System?

The Journey Of Lisinopril In the Human Body

The journey of medicine in the human body undergoes many stages. Metaphorically speaking, it’s a voyage of a tablet that makes some influential discoveries by treating the condition. On this journey, people are a bit confused about the duration of the whole trip.

The other side of your curiosity related to your question seems practical, i.e. health consciousness, because Lisinopril gets interacted with other medicines.

This article is about a medicine called Lisinopril and its presence in the body. Let’s start the journey, Bon Voyage!

The Arrival Of Lisinopril

Lisinopril is a hypertension patient’s first choice. It normalises the blood pressure in an instance. The beauty of its effectiveness lies in the simple working system.

Lisinopril inhibits the production of angiotensin II and widens the blood arteries to supply blood and oxygen to the important body parts. During Hypertension, the heart is under immense pressure to pump blood.

You can also buy lisinopril online from a certified online pharmacy but it is recommended to get a doctor’s prescription first.

How Long Does Lisinopril Stay In Your Body?

After calming down the blood pressure, many folks are confused about the title mentioned above. Lisinopril takes about 48 to 60 hours to be completely flushed out of the body.

If it controls the blood pressure in such a low time, how can it take such a duration to exit?

Our body works in a uniform system of metabolism. Metabolism, in simple terms, is a process of absorption and mixing into the bloodstream then the medicine is also transferred into various elements of the human body. First, know how much time the medication takes to eliminate half of its life? (Lancaster, S.G. and Todd, P.A., 1988)

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The Half-Life Journey Of Lisinopril

Lisinopril or even any other medicine time is observed into half-life. According to legit sources, the Half-life of Lisinopril is about 12.6 hours. It means it takes about this much time to eliminate half of its quantity. Now let’s move toward the gallery of calculations.

As mentioned above, Lisinopril takes about 48 to 60 hours to push off from the system. Whereas, half-life of lisinopril  is 12 hours then why does lisinopril take such a long time to fully exit from your body?.

The answer is simple, Half-life itself works in a structured approach. It takes five half-lives of Lisinopril to exit from the system completely. (Lancaster, S.G. and Todd, P.A., 1988)

Mathematically 12*5=60 or 12*4=48.

Factors Affecting Lisinopril Stay

Every voyage has some obstacles or factors that slow down the whole trip. Parallelly it is also the same in the case of Lisinopril. Various factors aid in increasing the exit duration. They are as follows:

Weight: Weight is one of the reasons that slows down the metabolism process. Excessive fat cells in the body can pressurise the liver’s capacity to metabolise the medicine.

Age: Age is the stage of life. With the increase in age, there are also changes in the body. Older adults have a slow absorption capacity as the body parts are also losing their capability. Same as in children, their systems are not grown fully to absorb drugs faster.

Metabolism rate: Metabolism rate depicts how fast your body absorbs or digests the medicine. Faster the metabolism, the faster the exit duration.

Dose Frequency: The dosage pattern you follow affects the presence of the medicine. Missed doses or extra doses are common factors in increasing medicine stay.

Health conditions: Healthy body and the immune system helps to utilise the medicine properly and vice versa. Long term health conditions can cause a slow rate of dispersing the medication.

As we recently stated, it is also found in other body elements. For this, lab tests are conducted.

Can Lab Tests of Urine/Hair/ Blood Trace Lisinopril in Body?

Tests are conducted if your doctor feels you are not taking medication in a timely manner.

Another reason can be clinical purposes

  • Urine: Lisinopril stays about 1 to 2 days.
  • Hair: Hair tests show Lisinopril found for 90 days after the last dose you have taken.
  • Blood: Lisinopril stays for three days in the blood. The number is based on half-life.

How Quickly Lisinopril Lowers Blood Pressure?

The Lisinopril mechanism makes the medicine a good option for Hypertension. It lowers blood pressure within 1 hour. For maximum effectiveness, it takes about 6 hours. We can say that the peak performance of Lisinopril is 6 hours.

What If You Stop Taking Lisinopril?

You should remember the first thing, if you are stopping some medicine, you should immediately inform a health expert. Better not to make a decision which can avail troubles.

If you stop consuming medicine, there are chances of rising blood pressure. As your body becomes adapted to the mechanism, it can lead to heart stroke or rebound Hypertension.

How To Detox Lisinopril Faster?

There is no fast method to detox lisinopril. Most people do not face any symptoms after stopping Lisinopril, but their blood pressure can rise. Detox depends on the dose frequency, duration, and whether you’re taking other ACE inhibitors.

Better to talk with your consultant before stopping the dose. Informed decisions are always better.


Lisinopril is a good and potent medicine for Hypertension. People are often blank about what goes in their bodies and ends up with unanswered questions.

The heart is the core of the human body that helps to pump blood and oxygen to the whole body. Disturbance in blood flow level results in serious issues. Lisinopril helps to maintain blood pressure level.

The Medicines exit time depends on several factors, observing the overall behaviour of medicine mechanism, one can quickly clear his doubts on his own.

Lastly, our medical voyage has come to an end.

Lisinopril vs Losartan

Lisinopril vs Losartan

In every house, we come across individuals suffering from one or the other health issue. It is observed that high blood pressure is a very common ailment.

As per the American College of Cardiology and American Heart Association nearly half of adults in the US (47%, or 116 million) have hypertension.

Only about 1 in 4 adults (24%) with hypertension have their condition under control. As we compare between men and women, a percentage of men(50%) have a higher blood pressure than women(44%).

So what exactly is blood pressure? Blood pressure is the pressure used by the blood against the walls of your arteries to help circulate blood across various body parts.

The normal blood pressure range is less than 120 on top and less than 80 on the bottom. High blood pressure occurs when your blood applies pressure that is higher than this range. It is also known as hypertension.

Oftentimes, high blood pressure is also termed a “silent killer” because you may not experience any symptoms indicating a problem with blood pressure. A few people may experience headaches, nosebleeds, or shortness of breath.

Food, medicine, lifestyle, health conditions, age, and genetics cause high blood pressure. High blood pressure can damage blood vessels of the brain, heart, and kidneys resulting in a stroke, heart failure, or kidney disease.

High blood pressure should not be taken lightly. It should be treated as soon as possible to avoid unnecessary complications. Lisinopril and Losartan are medicines that are mainly used to treat high blood pressure.

Do you know about Lisinopril and Losartan?

Lisinopril is an angiotensin-converting enzyme(ACE) inhibitor. It treats high blood pressure, and heart failure improves survival in people who had a heart attack, and also prevents future heart attacks.

It is not available over the counter as it is a prescription-based drug though you can purchase Lisinopril online from a certified online pharmacy it is recommended to get a doctor’s prescription first.

Lisinopril, which is an ACE inhibitor, means it blocks the action of ACE enzymes in the renin-angiotensin system(RAS).

Lisinopril prevents angiotensin-I from being converted to angiotensin-II.

By blocking the production of angiotensin-II, Lisinopril keeps blood vessels open and relaxed which lowers Blood pressure. (Lancaster, S.G. and Todd, P.A., 1988)

Losartan is known as an Angiotensin-II receptor blocker. Losartan is used to treat high blood pressure, stroke risk, and kidney problems associated with diabetes.

with a proper doctor’s prescription, you can also purchase Losartan online from a certified online pharmacy.

Losartan blocks the action of Angiotensin-II.

Angiotensin-II is a substance that narrows blood vessels and causes high blood pressure and it becomes hard to pump the blood.

Thus Losartan helps to relax your veins and arteries to lower the blood pressure and make it easier for your heart to pump blood. (Simpson, K.L. and McClellan, K.J., 2000)

Other uses of Lisinopril and Losartan?

 The other uses of Lisinopril and Losartan are as follows-

  • Heart Failure
  • Heart Attack
  • Stroke prevention
  • High blood pressure with diabetes
  • Lower heart attack and stroke risk
  • Kidney damage due to diabetes
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How can Lisinopril and Losartan be taken?

Lisinopril and Losartan are prescribed medications and are available in tablet form.

The tablet is taken orally once a day.

You can consume these tablets with or without food.

Consult your doctor,if Lisinopril tablets are hard to swallow as he can switch you to oral solution.

As there is no specific time to take Lisinopril and you can consume it anytime in the day.But it is helpful if you take Lisinopril on a daily routine or at the same time every day.

Try to take Losartan at the same time every day, for most people it would be morning and you can also consume it during the night.

Does their dosage differ from each other?

Yes, their dosages differ from each other. Dosages are especially recommended by our health care providers which depend on several factors like age, weight, medical condition, the effect of medication, etc.

Lisinopril dosage strength usually ranges from 2.5mg to 40mg.

Dosage of Lisinopril can vary depending on whether it is being used for hypertension, heart disorders, etc

The initial dosage starts at 2.5mg to 5mg a day, which can be increased up to 40mg a day.The recommended dose of Lisinopril for high blood pressure is 10mg once a day.

Losartan is also used to treat multiple conditions.So dosing will vary and also depends on each individual.

The initial dose of Losartan for high blood pressure is 50mg taken once a day, the dose can also increase up to 100mg per day or it can be taken all at once or split into two doses like 50mg twice a day.

How long do Lisinopril and Losartan stay in your system?

It is hard to define each medication and for how long it stays in your system. But if we know the half-life of a drug we can easily identify how long medication stays in our system.

After consuming Lisinopril, the half-life is about 12-hours and Lisinopril stays in your system for about 48 to 60 hours.

After consuming Losartan, the half-life is about 2 hours and Losartan takes around 6 to 9 hours to stay in your system. 

How fast do Lisinopril and Losartan work?

Lisinopril starts working as soon as you take your first dose. In clinical studies, many people have observed that their blood pressure is lowered within one hour of taking their first dose. Thus it shows maximum effectiveness within 6 hours. (Lancaster, S.G. and Todd, P.A., 1988)

Losartan is found to be the safest option for long-term treatment. Losartan starts to reduce the blood pressure within one hour but it may take 3 to 6 weeks to fully treat your condition. (Simpson, K.L. and McClellan, K.J., 2000)

Side Effects of both the medication

Both medications show similar side effects which may be noticed during the start of your treatment and your symptoms may go away within a week.

The common side effects are-

  • You may feel dizzy or unsteady. The chances of fainting increase due to weakness.
  • Headache is the most common symptom. Sometimes it may also lead to lightheadedness and it becomes hard to concentrate.
  • Both medications cause a respiratory tract infection which leads to Cough.

           During coughing something irritates your throat or airways.

  • You may also feel fatigued. It is a daily lack of energy and unusual or excessive whole-body tiredness not relieved by sleep.
  • By taking this medication you may notice an upset stomach and loose, watery stools that are difficult or painful to pass which is also called Diarrhoea.
  • You may also notice normal chest pain which may lead to trouble in breathing and also lowers blood pressure.

If we compare both the medications, Losartan causes fewer side effects than Lisinopril. Lisinopril shows severe side effects like-

  • Lisinopril can cause you persistent cough. From the start of your dose or if the doctor increases the amount of dose you may notice continuous cough which may be harmful further. It has been observed the coughing continues until you stop the treatment. Losartan does not cause cough and is a good alternative option.
  • If you consume Lisinopril there are utmost chances of Angioedema.

           Angioedema is swelling of the lips, mouth, tongue, and throat. The swelling can be serious so you immediately need medical help.

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Who can’t take Losartan and Lisinopril?

  • It is not safe for children who are below six years old.
  • The usage of Lisinopril and Losartan should be avoided in pregnant women and breastfeeding mothers as they are very dangerous for developing fetus and could cause serious birth defects or even death.
  • Elderly people can take both the medication but the work will be slow due to smaller amounts dosage.
  • Both the medication changes the level of potassium in the blood so avoid the use of potassium-related foodstuffs and medication.
  • If you ever had any type of allergic reaction by using any medication, supplements, vitamins, etc.
  • If you are taking other treatments besides lisinopril and losartan. Don’t combine and take this medication at the same time.
  • Losartan and Lisinopril may be not effective in people of the African desert because they show tendency towards a low renin state and lower cardiac output with increased peripheral resistance.

Is Losartan and Lisinopril the same?

No, Losartan and Lisinopril are different medications that work on various conditions. Since they belong to different drug classes.But both the medications work on the renin-angiotensin system and also they work on different parts of the system. But both medications lower blood pressure and are used for heart and kidney problems. They also differ in dosing, warning, price, etc.


Lisinopril is an ACE inhibitor that treats various heart disorders. Losartan is an ARB which treats heart disorders and kidney problems. They both treat the same conditions but work differently.

Lisinopril works faster than Losartan. However, the side effects of Lisinopril are more. It also stays longer in your body. We conclude that Losartan is a better medicine to treat high blood pressure in the long term.

Consult your health care provider before taking both medications as they know which suits best for your condition.

Ensure that you are well hydrated before taking lisinopril, as it may make you dizzy.

Lisinopril and Losartan interact with alcohol and cause sedative effects. This increases the risk of blood pressure getting too low and can be dangerous if we drive or use other machinery.

Severe side effects of lisinopril are persistent and dry cough as Losartan shows fewer side effects than lisinopril, so we can switch them for side effects.

Can You Take Lisinopril and Ibuprofen Together?

Can You Take Lisinopril and Ibuprofen Together?

We know that Medications are an excellent way to treat our health problems and relieve our pain.But what if two medications are combined and give you satisfying results?

Blood pressure and pain are different conditions connected to our body. But what if they occur at the same time? Can they be treated?

For instance-If, we take medication for blood pressure and suddenly there is back pain. Can we take other medicine for it? Can we consume them together or not? Let’s find out about Lisinopril and Ibuprofen.

Why is Lisinopril used?

Lisinopril is an antihypertensive drug. Lisinopril is a prescribed medication to treat high blood pressure, heart failure, and heart stroke.

Lisinopril is sold under several brand names like Prinivil, Zestril, and Qbrelis. Buy Lisinopril online from a certified online pharmacy. (Olvera Lopez E, Parmar M, Pendela VS, et al)

Why is Ibuprofen used ?

Ibuprofen is a pain reliever drug.It reduces fever and treats inflammation, minor aches, joint pain, sore throat, cold, etc.

Ibuprofen is also prescribed for arthritis and osteoarthritis in people. Ibuprofen is sold under common brand names Advil, Motrin, and Nuprin. Order Ibuprofen online from a certified online pharmacy. (Ngo VTH, Bajaj T)

Mechanism of Lisinopril

Lisinopril belongs to a group of medication ACE(angiotensin-converting enzyme)inhibitors. Lisinopril works on angiotensin systems and blocks enzymes called ACE.

This enzyme produces a hormone called angiotensin-II, which helps regulate blood pressure by causing blood vessels to constrict. It blocks the production of angiotensin-II and lowers blood pressure by relaxing the veins and arteries in the body. (Olvera Lopez E, Parmar M, Pendela VS, et al)

Mechanism of Ibuprofen

Ibuprofen belongs to a drug class called a non-steroidal anti-inflammatory drug (NSAID). When cells in your body are injured, the cells release certain chemicals in response called prostaglandins.

These chemicals cause inflammation and amplify signals coming from nerves. Thus, they increase the pain you feel. Ibuprofen works by blocking the prostaglandins, and you feel relief.  (Ngo VTH, Bajaj T)

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Can you take Lisinopril and Ibuprofen together?

If you are a patient with high blood pressure, you need to be attentive and careful while consuming OTC pain medication.

Some NSAIDs can be risky for people with high blood pressure, like Ibuprofen, naproxen sodium, ketoprofen, etc.

Effects of Lisinopril and Ibuprofen on Kidney

Ibuprofen initially passes through the kidneys. The kidneys are safe and healthy when the blood pressure in the kidneys goes from high to normal. (Ngo VTH, Bajaj T)

But when we have a kidney problem, the blood pressure goes from normal to low, which leads to damage to the kidneys, which can happen to patients who consume ACE inhibitors and get dehydrated or develop low blood pressure from other causes.

Therefore if we mix Ibuprofen with Lisinopril, things can get even worse. (Olvera Lopez E, Parmar M, Pendela VS, et al)

Effects of Lisinopril and Ibuprofen on Stomach and Intestine

If we regularly use Ibuprofen, there are chances of stomach and intestinal bleeding, and if we combine both, it can show harmful effects on the intestine and stomach. (Ngo VTH, Bajaj T)

Ibuprofen and all NSAIDs irritate and erode the lining of the stomach and intestines, causing an ulcer or sore, which leads to bleeding. Some patients who take Ibuprofen have noticed and reported passing blood in their stool after one dose of Ibuprofen.

However, patients who don’t have stomach and intestine disorders don’t have such bleeding problems. (Olvera Lopez E, Parmar M, Pendela VS, et al)

Effects of Lisinopril and Ibuprofen on Heart

There is a risk of a heart attack while consuming Ibuprofen. Some people have experienced heart attacks soon after taking Ibuprofen. This usually occurs in people with heart disease or a history of heart attack and after open-heart surgery. (Ngo VTH, Bajaj T)

Ibuprofen makes ACE inhibitors(Lisinopril) less effective and increases blood pressure, making it hard to control.The doctor may advise this patient to monitor their blood pressure to stay safe regularly. (Olvera Lopez E, Parmar M, Pendela VS, et al)

What are the other Pain Medications we can take with Lisinopril?

Other NSAID pain relievers may be less dangerous, like Aspirin and Acetaminophen.

  • Aspirin-Low dose of Aspirin, 75mg a day, is safe to take with Lisinopril for people with hypertension.
  • Acetaminophen appears to be the safest option that doesn’t raise the blood pressure, and you can take it with Lisinopril.

Dosages of Lisinopril

Dosages are recommended by our health care providers, which depend on several factors like age, weight, medical condition, the effect of medication, etc.

Dosage of Lisinopril can vary depending on whether it is being used for hypertension, heart disorders, etc. The recommended dose of Lisinopril for high blood pressure is 10mg once a day.

Dosages of Ibuprofen

Dosage for mild to moderate pain might be as follows-

Adults can consume 200mg to 400 mg every 4 to 6 hours. The maximum dosage for adults is 3200mg per day

Side Effects of Lisinopril and Ibuprofen

You may notice some common side effects during the start of your treatment which may last long till one week. Consult your healthcare provider if side effects don’t fade within a week.

Common side effects of Lisinopril

  • When you consume Lisinopril, you may notice some irritation in the throat, leading to Cough.
  • You may feel dizziness or feel weak and unsteady. You may also experience a false sense of motion.
  • Headache is a common symptom of Lisinopril.
  • You may be Fatigued, which is unusual, or whole-body tiredness not relieved by sleep.
  • You may suffer from diarrhoea and notice loose, watery stools.
  • In the initial period, Lisinopril results in mild chest pain and causes low blood pressure. (Olvera Lopez E, Parmar M, Pendela VS, et al)

Common side effects of Ibuprofen

  • During the start of your treatment, you may feel like vomiting because of your stomach discomfort, which is called Nausea.
  • If you vomit soon after taking Ibuprofen, it is possible that your body didn’t have the chance to absorb it.
  • You may feel lightheadedness or a mild Headache.
  • It becomes difficult or painful for you to pass the stools, which are hard, dry, and lumpy, called constipation.
  • It results in Diarrhoea, which is loose and watery stools.
  • You may feel weak or dizzy, or tired; you might feel sleepy or tired during the day.
  • Symptoms may occur like indigestion or upset stomach, and stomach pain. (Ngo VTH, Bajaj T)

Who can't take Lisinopril?

  • Those who had allergic reactions with Lisinopril or any other medication, herbs, supplement, vitamins, and ever had a history of angioedema(swelling of mouth, tongue, throat).
  • If you are a patient with a kidney disorder or ever have dialysis, there is a risk of severe side effects with Lisinopril. Please consult your doctor so they can adjust the medication.
  • For people with diabetes because the medication can affect blood sugar levels.
  • Lisinopril is avoided in pregnant women as it is not safe for the foetus.
  • There is also a risk for older patients with Lisinopril, so they are suggested for low doses.
  • Lisinopril is not recommended for children younger than six years.
  • The medication may not work in Black patients.

See Deals On Lisinopril

Who can't take Ibuprofen?

  • Don’t use it if you ever had an allergic reaction to Ibuprofen or other NSAIDs or medication.
  • If you ever had a heart attack, asthma, liver and kidney disease. Avoid the usage if you ever have high blood pressure or stomach and intestinal problems.
  • Ibuprofen is not recommended if the child is younger than six months old.
  • Usage of Ibuprofen should be avoided in pregnant women and breastfeeding mothers as it harms the foetus and causes problems in delivery.
  • Don’t take medication for a more extended period as they cause serious side effects, so elder patients above 65 are suggested a low dose for a short period.


Lisinopril is an antihypertensive drug that treats various heart disorders. Ibuprofen is a painkiller medication that treats minor aches, joint pain, inflammation, swelling, etc.

They both are different medications that work in different ways to treat conditions.

They differ in dosages, forms, and strength mentioned above. Be aware and careful while consuming both medications together.

Avoid the usage of Lisinopril with Ibuprofen as they show dangerous effects on the body. Other safest alternatives are available

Lisinopril treats high blood pressure, but there is a risk of causing insomnia(sleep disorders).

No, it does not affect our weight. Lisinopril is not known to cause weight loss or weight gain.

All NSAIDs affect the blood, including Ibuprofen. It slows down the clotting time. That means if we have a cut on our body, it may take longer to stop the bleeding.

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