How Long Does Chlorzoxazone Stay In Your System?

How Long Does Chlorzoxazone Stay In Your System?

Chlorzoxazone is rapidly metabolized and eliminated in the urine, predominantly as the glucuronide in a conjugated form. In 24 hours, less than 1% of a dose of Chlorzoxazone is eliminated intact in the urine. Chlorzoxazone is a skeletal muscle relaxant prescribed as a supplement to rest, physical therapy, and other treatments to reduce pain and suffering caused by acute musculoskeletal problems. (Lucas, D., Ferrara, R., Gonzalez, E., Bodenez, P., Albores, A., Manno, M. and Berthou, F., 1999)

How Chlorzoxazone Works?

Chlorzoxazone suppresses multisynaptic reflex arcs involved in producing and maintaining skeletal muscle spasms of various etiologies at the level of the spinal cord and subcortical areas of the brain. The clinical outcome is a decrease in skeletal, muscular spasms, pain alleviation, and greater mobility of the affected muscles. (Cao, Y.J., Dreixler, J.C., Roizen, J.D., Roberts, M.T. and Houamed, K.M., 2001)

How To Consume Chlorzoxazone

Chlorzoxazone is available as a pill that must be swallowed. It’s often taken three to four times each day. Carefully follow the advice on the medication label, and if there is anything you don’t understand, ask your healthcare professional to explain it to you. Chlorzoxazone should be taken exactly as prescribed. Please do not consume more or less of it than your doctor has instructed. (Girre, C., Lucas, D., Hispard, E., Menez, C., Dally, S. and Menez, J.F., 1994)

Dosage

This medicine’s dosage will vary depending on the patient. Follow your doctor’s orders or the label’s instructions. Only the typical doses of this drug are included in the following information. If your amount of dose differs, do not alter it unless your doctor instructs you to.

The strength of the medicine determines how much you should take. Furthermore, the medical problem for which the drug is being used determines the number of doses you take every day, the interval between doses, and the length of time you take medicine.

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Side Effects Of Chlorzoxazone

Side Effects of Chlorzoxazone

Some of the side effects of Chlorzoxazone include:

  • Gastrointestinal bleeding
  • Drowsiness
  • Dizziness
  • Lightheadedness 
  • Malaise

How other Drugs affect Chlorzoxazone?

When Chlorzoxazone is used with other sleepy medicines, the impact can be amplified. Before taking an opioid prescription, a sleeping pill, a muscle relaxant, or a treatment for anxiety or seizures, consult your doctor. Other pharmaceuticals, such as prescription and over-the-counter medicines, vitamins, and herbal items, may interact with Chlorzoxazone. Tell your healthcare professioal about all of your existing medications, as well as any new or discontinued medications.

Safety measures to keep in mind before taking Chlorzoxazone

It’s critical that your doctor monitors your progress at frequent intervals to ensure that the treatment is working correctly and rule out any side effects. While taking this medication, you may get liver problems. If you have more than one of the symptoms mentioned above, stop taking this prescription and consult your doctor right away. Alcohol and other CNS depressants will be amplified by this medication (medicines that make you drowsy or less alert). Antihistamines or allergy medicine; sedatives, tranquilizers, sleeping medicine; prescription pain medicine or opioids; barbiturates; seizure medicine; or anesthetics, including some dental anesthetics, are all examples of CNS depressants. Before using any of these medications while taking Chlorzoxazone, see your doctor or dentist. (Jackson, J. and Anania, F.A., 2007)
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