Tylenol or acetaminophen has been present for a long time. It has proven its efficacy over the years. Tylenol reduces fever, menstrual cramps, toothaches, back pain, and migraines. In a nutshell a multipurpose pain reliever.

As per the sources and research, Tylenol affects blood pressure. Various research papers and journals state Tylenol raises blood pressure after a sure consistency in use. Let's get your answer through a valid study.

Do Pain relievers raise blood pressure?

Acetaminophen is associated with decreasing pain or inflammation. As it has been in the market for a long time, there is a misconception about its working. It usually works by stopping the production of prostaglandin in the nervous system, and it decreases pain.

The connection between Tylenol and blood pressure is well displayed. You might have seen the official sites of Tylenol claiming that it did not affect blood pressure, but studies from the national library of science suggest some differences.
Tylenol is a non aspirin pain reliever, and as per the found studies, it raises blood pressure (Prisant, L.M. and Carr, A.A., 1989).

The Proof Centre:

Regular Acetaminophen Use and Blood Pressure

In a study conducted to observe the effect of acetaminophen on blood pressure, 110 individuals were given 1g of acetaminophen four times a day for two weeks. At the beginning and end of each treatment, the blood pressure was measured every 24 hours.

Results: Out of 110, 103 patients who completed the study, regular intake of 4g acetaminophen increased blood pressure in the mean daytime compared to placebo. Hence it clears acetaminophen increases blood pressure (Maxwell, E.N., Johnson, B., Cammilleri, J. and Ferreira, J.A., 2019).

Is There a Possibility Of Tylenol Lower Blood Pressure?

According to new research, intravenous acetaminophen lowers blood pressure. Intravenous systems help those who are unable to swallow tablets.

The Expert Box:

Thomas, an assistant professor in the biomedical sciences department at the University of Copenhagen, Says -

"Recent studies suggest it is quite a sizable drop. We are, for example, talking in the range of 25-30 mm Hg from a systolic pressure of 120, and we now believe that we know the mechanism underlying this dangerous side effect"

The above statement was made based on rat studies.

Can Tylenol Raise the Blood Pressure Of Hypotensive Patients?

As the study suggests, it can raise the blood pressure of people consuming Tylenol and increase hypotension. Certainly, Tylenol can raise the blood pressure of high blood pressure patients.

The Expert Box:

Dr. Donald Lloyd of the American Heart Association, Says

"An increase in the blood pressure of people with hypertension is always wrong.
Together, Tylenol can raise the blood pressure of hypertension patients."

Can You Take Tylenol With Blood Pressure Medications?

Tylenol raises blood pressure; the trials showed a specific spike in the blood pressure levels; however, it doesn't mean people on hypertension medication cannot use it at all.
For them, the lowest dose of Tylenol will be ok. Tylenol's two regular strengths of 325 mg tablets every six hours or two extra powers of 500 mg tablets every eight hours.

If you still feel your blood pressure is rising, you can alter it to a lower dose under the supervision of a doctor.

Also, Read


Tylenol leads to a rise in blood pressure. As stated in the studies, many official sites will explain it doesn't affect blood pressure. Although the reputed studies and research shows some differing pictures. However, high BP patients can still use Tylenol for their aches and pains under the supervision of their doctor.


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