Ketorolac Tromethamine is sold under the trade name; Toradol. It is a medicine under the drug class named as non-steroidal anti-inflammatory drugs (NSAIDs).

Toradol is a potent analgesic (painkiller) and as well as an anti-inflammatory agent. It is used to heal moderate to severe types of pain.

Medicines That Make You Feel Sleepy

There is a list of medicines that cause sleepiness

  • Antihistamines (Cetirizine, loratadine, and hydroxyzine)
  • Muscle relaxants (carisoprodol and tizanidine)
  • Antidepressants (escitalopram, citalopram, paroxetine, and fluoxetine)
  • Topiramate
  • Beta-blockers (metoprolol, carvedilol, bisoprolol, and propranolol
  • Benzodiazepines (lorazepam , diazepam)

Does Toradol Make You Sleepy?

Toradol does not affect brain centers. Instead, it acts on the body to help reduce pain. It might release some sedative properties that make you sleepy, but in rare cases, Patients feel sleepy.
These medications treat pain but also cause sleepiness and probably habit-forming (addictive).

NSAIDs like Toradol are used to treat pain, but it does not belong to the class of opioids. Both are not in the same style and work differently; their side effects are also different. Toradol is less likely to produce an impact on the brain. Instead, it acts on other parts of the body — this tends to make no dependency. Migraines can impact on the sleeping pattern al though Toradol  is also useful in migraines.

Specific Warnings Are Associated While Taking Toradol, Such As

Patients suffering from gastrointestinal, heart, respiratory, kidney, and neurological disorders are at greater risk of experiencing the adverse effects of Toradol.
It does not prescribe for patients with heart attacks, stomach ulcers, asthma, etc.
It is also avoided during pregnancy due to its risks.

Many medicines interact with Toradol

  • Other NSAIDs (Aspirin)
  • Anti-seizure medicines (Phenytoin) 
  • Anti-hypertensives (hydrochlorothiazide, furosemide)
  • Anti-cancer (Methotrexate)

The interactions has the possibility to make you sleepy.


Toradol cannot cause sleepiness as it does not have an association with the brain's sleep centers. It has been suggested through sources that 1-10% of patients claim that they feel sleepiness and drowsiness while taking Toradol. This might be due to the sedative elements released by Toradol.

It is still doubtful because little data and research are available to justify the above statement as it has not involved a wide variety of clinical trials.


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