04 Nov 2022
Losartan is an angiotensin receptor blocker (ARB) used to treat high blood pressure/hypertension. It is a Reno protective drug used in kidney problems caused by type 2 diabetes and used to decrease the risk of stroke/ Heart attack caused by high blood pressure and to treat heart enlargement commonly known as tachycardia.
Losartan is a very effective and well-tolerated medicine for diabetic erectile dysfunction. It is the only antihypertensive drug that does not cause erectile dysfunction and is safer. Losartan is only available in tablet form (Simpson, K.L. and McClellan, K.J., 2000).
Viagra, a brand name for sildenafil, is an oral drug of choice for erectile dysfunction. Sildenafil is a phosphodiesterase inhibitor that relaxes the vessels, increases blood flow to the penis, and contributes to erectile function. Phosphodiesterase (PDE) inhibitors are of different types and control various parts, PDE5 is found in penis erectile tissues.
Sildenafil is a selective PDE5 inhibitor, and studies show it is helpful for erectile dysfunction in 69% of people. Viagra is taken by mouth or by injection into a vein (Langtry, H.D. and Markham, A., 1999).
How Viagra Became An Ed Medicine Rather Than A Blood Pressure Medicine?
Viagra was developed in 1991 for the treatment of angina, but in 1998 it was used for the treatment of impotence. The most common cause of sexual dysfunction in men is vascular, and these Vascular causes include atherosclerosis, high blood pressure, and high cholesterol in the blood.
Viagra is a selective PDE5 inhibitor, increasing the platelet antiaggregatory activity of nitric oxide and inhibiting platelet thrombus formation and peripheral arterial-venous dilatation.
It helps to fill the penis with blood by dilating arteries, increasing blood flow, enhancing the ability to get an erection, and enabling men with erectile dysfunction to respond to sexual stimulation. Viagra is mainly used for erectile dysfunction but also affects blood pressure by relaxing vessels.
Does Losartan Works When You Take Viagra And Losartan Or Vice Versa?
Both drugs have different classes, so they have different action modes and work accordingly.
Losartan works by blocking angiotensin receptors, which relax vessels to increase blood flow and oxygen to the heart. In contrast, Viagra works by blocking phosphodiesterase and relaxing the vascular tissues, mainly penile erectile tissues.
Both drugs decrease blood pressure in different ways. Viagra adds to the blood pressure-lowering effects of losartan and reduces them together. They lower the blood flow to the heart and brain, causing severe problems that may lead to coma.
What Are The Effects of Losartan And Viagra Combination?
Losartan and Viagra decrease blood pressure in different ways. When we take these medications in combination, they double up the action of reducing blood pressure and cause life-threatening low blood pressure levels.
A single dose of Viagra can lower the systolic blood pressure by 8mmhg and diastolic blood pressure by about 5mmhg. Avoid using these drugs together because both increase dilatation of the vessels and cause a decrease in blood flow to the body's organs, leading to shock.
Talk to your doctor if you feel dizziness, lightheadedness, weak or rapid pulse, cold and sweaty skin, or any other symptom. It is better not to use this medication without a prescription from the doctor (Li, W.J., Xu, M., Gu, M., Zheng, D.C., Guo, J., Cai, Z. and Wang, Z., 2017).
Is Losartan Also Useful In Erectile Dysfunction?
All the medications for high blood pressure cause erectile dysfunction. Most people stop blood pressure medicines because they may interfere with sexual function. Now high blood pressure is treated by the newest drug, losartan, which controls blood pressure and positively affects sexuality.
It works by blocking angiotensin receptors. Angiotensin is a hormone that increases blood pressure and contributes to sexual dysfunction. Losartan improves sexual dysfunction in two ways. First, it acts on the blood vessels of the penis that are damaged by high blood pressure and supply them with blood through relaxation. Secondly, it works on the brain to improve the body's wellness, but should not be used for ED as there are many prominent ED based medications available just like Viagra (Chen, Y., Cui, S., Lin, H., Xu, Z., Zhu, W., Shi, L., Yang, R., Wang, R. and Dai, Y., 2012).
Conclusion
Losartan and Viagra are two different drugs used to treat high hypertension and erectile dysfunction, but these cannot be used together. Losartan is an antihypertensive drug that is safer to use for erectile function. It is effective for sexual dysfunction and improves erectile dysfunction but there are other options available which is made only for ED.
Viagra is a drug to treat erectile dysfunction, but it also lowers blood pressure because it relaxes tightened vessels and increases blood flow. Take these medications with the proper dosage prescribed by your doctor and don’t try to mix them together.
