Chlorzoxazone reduces pain and muscle stiffness caused by muscle sprains and strains. It is an FDA-approved prescription drug. Chlorzoxazone belongs to the drug class centrally acting skeletal Muscle relaxers. It works best when combined with rest and physical therapy.

Narcotics are some of the substances used to treat moderate to severe pain but can be highly addictive. Narcotics are very similar to opiates, but they are not made from opium.

Chlorzoxazone is used to treat pain, but it is not a narcotic. It belongs to drug class skeletal muscle relaxers which are not narcotics. However, some muscle relaxers like Valium and Soma are considered narcotics even though they are muscle relaxers.

Chlorzoxazone works by affecting the central nervous system and has sedative effects on the body. But it does not come under the controlled substance category.

Are Muscle Relaxers A Controlled Substance?

Not all muscle relaxers are controlled substances. Even the mechanism of these muscle relaxers acts on the central nervous system, spinal cord, and brain; they are not controlled substances.

But some muscle relaxers such as Soma and Valium are considered controlled substances as people might abuse them and depend on them.

Mechanism Of Chlorzoxazone

The exact working of Chlorzoxazone is unknown, but scientists assume it targets the spinal cord and subcortical levels of the brain to prevent multisynaptic reflex arcs involved in producing and maintaining muscle spasms. This results in a decrease in muscular and skeletal spasms, pain, and greater mobility of the muscles.

Forms And Strength Of Chlorzoxazone

This medication is available in tablet form in the strength of Chlorzoxazone 250 milligrams, 500 milligrams, 375 milligrams, and 750 milligrams.

How To Take?

One should take Chlorzoxazone along with proper rest and therapy. One should take it 3-4 times a day per the doctor's direction. It can be taken before having food or after. One should not increase or decrease the dose without taking medical help.

Dosage Of Chlorzoxazone

The recommended standard dosage for muscle relaxation is 500 milligrams (mg) three or four per day for adults. If needed, your healthcare professional may change your dosage.

The maximum dosage is 750 milligrams three or four times per day.

In case you missed the dose, take the dose immediately. Do not take the dose if the next dose is close. Do not take two doses together.

Nausea, diarrhoea, vomiting are some symptoms of overdosage of Chlorzoxazone. Get emergency medical help to prevent further negative risks.

Side Effects Of Chlorzoxazone

The common side effects of Chlorzoxazone include:

  • Drowsiness
  • Dizziness
  • Light-headedness
  • Weakness
  • Skin rash or itching
  • Yellowing of the skin or eyes
  • Stomach pain

Consult your medical health practitioner if you observe any such side effects.

Before Taking Chlorzoxazone

Your healthcare professional must note your progress at frequent intervals to ensure that the drugs work correctly and rule out any adverse effects.

Do not consume it if you are under 18.

While taking this drug, you may have liver issues. If you have more than one of the side effects mentioned above, stop taking this medication and consult your healthcare professional right away.

Pregnant and breastfeeding women should get medical help before taking medicine as the effects may affect their health (O'Shea, D., Davis, S.N., Kim, R.B. and Wilkinson, G.R., 1994).

Things To Keep In Mind While Taking Chlorzoxazone

While taking Chlorzoxazone, one should not indulge in activities that require a lot of attention and carefulness.

Consuming alcohol can make the person feel drowsier, and the sedation effect may increase.

One should follow the proper dosage as prescribed as it might turn into addiction because it affects the CNS.

Terminating the medication may also have negative effects on the health (Umar, M.T., Bello, S.O., Chika, A. and Abdulmumini, Y., 2020).

Is Chlorzoxazone The Same As Soma?

Though both these medications are muscle relaxers, Chlorzoxazone is different from Soma. It is a different drug and not a controlled substance, unlike Soma.

What Is Chlorzoxazone Similar To?

Chlorzoxazone is similar to muscle relaxers such as Robaxin and Flexeril.

Drug Interactions Of Chlorzoxazone

When Chlorzoxazone is used with other medicines, the side effects can be amplified. Some of them include:

  • Opioid prescriptions
  • Sleeping pills
  • Muscle relaxants
  • Anxiety or seizure medications
  • Antihistamines or allergy medicine
  • Sedatives
  • Tranquilizers
  • Barbiturates
  • Anaesthetics,

Before using any of these drugs along with Chlorzoxazone, consult your healthcare professional.


Chlorzoxazone is a widely used muscle relaxant. It helps to treat muscle pain and spasms. It is not a narcotic substance, but it might be addictive. Following proper dosage and instructions provides effective results. Consult your doctor and inform about the medical history to reduce the risk of negative effects.


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