The Journey Of Lisinopril In the Human Body

The journey of medicine in the human body undergoes many stages. Metaphorically speaking, it's a voyage of a tablet that makes some influential discoveries by treating the condition. On this journey, people are a bit confused about the duration of the whole trip.

The other side of your curiosity related to your question seems practical, i.e. health consciousness, because Lisinopril gets interacted with other medicines.

This article is about a medicine called Lisinopril and its presence in the body. Let's start the journey, Bon Voyage!

The Arrival Of Lisinopril

Lisinopril is a hypertension patient's first choice. It normalises the blood pressure in an instance. The beauty of its effectiveness lies in the simple working system.

Lisinopril inhibits the production of angiotensin II and widens the blood arteries to supply blood and oxygen to the important body parts. During Hypertension, the heart is under immense pressure to pump blood.

You can also buy lisinopril over the counter from a certified online pharmacy but it is recommended to get a doctor's prescription first.

How Long Does Lisinopril Stay In Your Body?

After calming down the blood pressure, many folks are confused about the title mentioned above. Lisinopril takes about 48 to 60 hours to be completely flushed out of the body.

If it controls the blood pressure in such a low time, how can it take such a duration to exit?

Our body works in a uniform system of metabolism. Metabolism, in simple terms, is a process of absorption and mixing into the bloodstream then the medicine is also transferred into various elements of the human body. First, know how much time the medication takes to eliminate half of its life? (Lancaster, S.G. and Todd, P.A., 1988).

The Half-Life Journey Of Lisinopril

Lisinopril or even any other medicine time is observed into half-life. According to legit sources, the Half-life of Lisinopril is about 12.6 hours. It means it takes about this much time to eliminate half of its quantity. Now let's move toward the gallery of calculations.

As mentioned above, Lisinopril takes about 48 to 60 hours to push off from the system. Whereas, half-life of lisinopril  is 12 hours then why does lisinopril take such a long time to fully exit from your body?.

The answer is simple, Half-life itself works in a structured approach. It takes five half-lives of Lisinopril to exit from the system completely (Lancaster, S.G. and Todd, P.A., 1988).

Mathematically 12*5=60 or 12*4=48.

Factors Affecting Lisinopril Stay

Every voyage has some obstacles or factors that slow down the whole trip. Parallelly it is also the same in the case of Lisinopril. Various factors aid in increasing the exit duration. They are as follows:

Weight: Weight is one of the reasons that slows down the metabolism process. Excessive fat cells in the body can pressurise the liver's capacity to metabolise the medicine.

Age: Age is the stage of life. With the increase in age, there are also changes in the body. Older adults have a slow absorption capacity as the body parts are also losing their capability. Same as in children, their systems are not grown fully to absorb drugs faster.

Metabolism rate: Metabolism rate depicts how fast your body absorbs or digests the medicine. Faster the metabolism, the faster the exit duration.

Dose Frequency: The dosage pattern you follow affects the presence of the medicine. Missed doses or extra doses are common factors in increasing medicine stay.

Health conditions: Healthy body and the immune system helps to utilise the medicine properly and vice versa. Long term health conditions can cause a slow rate of dispersing the medication.

As we recently stated, it is also found in other body elements. For this, lab tests are conducted.

Can Lab Tests Of Urine/hair/ Blood Trace Lisinopril In Body?

Tests are conducted if your doctor feels you are not taking medication in a timely manner.

Another reason can be clinical purposes

  • Urine: Lisinopril stays about 1 to 2 days.
  • Hair: Hair tests show Lisinopril found for 90 days after the last dose you have taken.
  • Blood: Lisinopril stays for three days in the blood. The number is based on half-life.

How Quickly Lisinopril Lowers Blood Pressure?

The Lisinopril mechanism makes the medicine a good option for Hypertension. It lowers blood pressure within 1 hour. For maximum effectiveness, it takes about 6 hours. We can say that the peak performance of Lisinopril is 6 hours.

What If You Stop Taking Lisinopril?

You should remember the first thing, if you are stopping some medicine, you should immediately inform a health expert. Better not to make a decision which can avail troubles.

If you stop consuming medicine, there are chances of rising blood pressure. As your body becomes adapted to the mechanism, it can lead to heart stroke or rebound Hypertension.

How To Detox Lisinopril Faster?

There is no fast method to detox lisinopril. Most people do not face any symptoms after stopping Lisinopril, but their blood pressure can rise. Detox depends on the dose frequency, duration, and whether you're taking other ACE inhibitors.

Better to talk with your consultant before stopping the dose. Informed decisions are always better.


Lisinopril is a good and potent medicine for Hypertension. People are often blank about what goes in their bodies and ends up with unanswered questions.

The heart is the core of the human body that helps to pump blood and oxygen to the whole body. Disturbance in blood flow level results in serious issues. Lisinopril helps to maintain blood pressure level.

The Medicines exit time depends on several factors, observing the overall behavior of medicine mechanism, one can quickly clear his doubts on his own. Lastly, our medical voyage has come to an end.


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