Gabapentin is a medicine mostly used to treat neuropathic pain and seizures. Although it is not used as an anti-sweating agent, it may have some potential to lessen sweating. Before taking any new medication, you must talk to your doctor to see if it's right for your condition and if it might cause any side effects.

Is Excessive Sweating A Big Concern?

Hyperhidrosis, or excessive sweating, can be a significant concern for some people. Social anxiety, embarrassment, and difficulty completing daily tasks are all possible side effects. Additionally, it may result in an unpleasant odor, fungal infections, and skin irritation. In severe cases, it can negatively affect a person's quality of life and daily functioning.

However, the condition is managed with various treatments, including antiperspirants, iontophoresis, botox, and surgery. Suppose you sweat more than your natural rhythm. In that case, you should see a doctor immediately because there may be underlying medical conditions such as thyroid problems, diabetes, or infection that need to be treated.

What Are The Main Causes Of Excessive Sweating?

Hyperhidrosis, also known as excessive sweating, can take many forms. The primary reasons include the following:

  • Hyperhidrosis focal primary: Without an underlying medical condition, this is the most common cause of excessive sweating. It is characterized by excessive sweating in body parts, including the face, palms, soles, and armpits.
  • Additional hyperhidrosis: An underlying medical condition like diabetes, menopause, thyroid problems, and certain medications can cause this kind of excessive sweating.
  • Mental or emotional conditions: Excessive sweating can also be caused by emotional disorders, stress, and anxiety.
  • Hyperhidrosis idiopathic: There is no known cause for this condition, which causes excessive sweating.

A Small Brief About Hyperhidrosis

The condition known as hyperhidrosis is characterized by excessive sweating that is unrelated to heat or physical activity. It can happen in particular body parts, like the armpits, palms, soles, and face, or it can happen more often.

The severity of the condition can vary greatly, with some individuals experiencing only mild discomfort and others experiencing significant social and emotional distress. 

Additionally, hyperhidrosis can cause skin irritation, fungal infections, and an unpleasant odor. Antiperspirants, iontophoresis, botox, and surgery are some treatment options.

Do Cancer Patients Sweats A Lot?

Night sweats, also known as excessive sweating, can occur at any time of day in cancer patients. Night sweats are frequently a symptom of advanced cancer and can be brought on by cancer itself, the treatment for cancer, or other cancer-related conditions.

Night sweats are more common in cancers like lymphoma, leukemia, and lung cancer. Infections and hormonal imbalances can also cause night sweats.

Can We Use Gabapentin As Anti Sweating Medication?

Although Gabapentin is mainly used to treat seizures and neuropathic pain, some studies suggest it could be used as an anti-sweating drug. However, it is neither a medication that is typically used for this purpose nor has it been approved for use in this manner by the FDA. Gabapentin affects the body's chemicals and nerves that cause seizures and some kinds of pain. It is not clear how exactly it involves sweating or how it works.

The Proof Center

Gabapentin in the treatment of severe sweating experienced by advanced cancer patients


In this study, the researchers examined the use of Gabapentin as a treatment for primary focal hyperhidrosis. It was a randomized, double-blind, placebo-controlled trial. Randomly assigned to receive Gabapentin or a placebo for four weeks, 32 patients with excessive sweating in the axillae (underarms) were included in the study.

According to the patients' self-assessments and gravimetric measurements, the study found that Gabapentin significantly reduced sweating. Also, the study found that Gabapentin was well tolerated and didn't cause serious side effects.

It is important to note that this was a small study with a precise sample size. More study is needed to confirm these findings and determine if Gabapentin's long-term safety and effectiveness in treating excessive sweating are both actual. Additionally, Gabapentin is not typically prescribed for this purpose and has not been approved by the FDA for use in this manner.

Are There Any Other Pills To Stop Sweating?

People or patients can take several medications to stop sweating too much, including:
Anticholinergics: These medications inhibit acetylcholine, a chemical involved in sweat production. Glycopyrrolate and oxybutynin are two examples of anticholinergic drugs.

Clonidine: This medication lowers blood pressure and makes you sweat less.
The toxin of botulism: Botox injections temporarily paralyze the sweat glands, reducing sweating.

Antidepressants with tricyclics: Although medications like imipramine and nortriptyline can be used to lessen sweating, they are typically not considered first-line treatments due to the possibility of side effects.

It is essential to remember that these medicines should only be taken under the direction and supervision of a physician because they may cause undesirable side effects and may not be appropriate for all patients. Not all patients may benefit from these medications, and some may need to experiment with various drugs before settling on the most effective one.

Can Gabapentin Be The Next On Anti Sweat Pills List?

Gabapentin has been looked into as a way to treat excessive sweating, but it hasn't been filtered and approved by the FDA for this purpose and isn't a medication usually used for this. More research is required to confirm the safety and efficacy of Gabapentin as a treatment for excessive sweating. The studies conducted on using Gabapentin for excessive sweating have been limited and have produced mixed results.


In conclusion, seizures and neuropathic pain are the primary uses of Gabapentin. However, despite studies suggesting this possibility, the FDA has not approved it for use as an anti-sweating medication.

Hyperhidrosis, also called excessive sweating, is a condition that can profoundly impact a person's life. Antiperspirants, iontophoresis, botox, and surgery are some available treatments. The article's study is a small trial with a small sample size; additional research is needed to confirm Gabapentin's safety and effectiveness as a treatment for excessive sweating.


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