Baclofen

Baclofen is an antispasmodic agent, a muscle relaxer; Baclofen is a medication that can be used to treat spasms, muscle pain, and stiffness in people with multiple sclerosis or spinal cord injury.

Baclofen was designed as a drug for treating epilepsy, and it was first made at Ciba-Geigy by the Swiss chemist Heinrich Keberle in 1962. It is sold under the brand name Lioresal.

Food and drug administration first approved it approved Baclofen on 30 October 2003. It is not classified as a controlled substance. Baclofen can be given in two ways orally (by mouth) or intrathecally (directly into the spinal cord). Baclofen can treat muscle spasms caused by conditions like spinal cord injury or multiple sclerosis.

In addition to being prescribed recreationally, Baclofen has also become increasingly popular among athletes looking to get an edge when competing against others.

How to Administer Baclofen?

Ensure that you’re following the directions carefully and drink plenty of fluids when taking this medication. You can also take it with food as long as you keep eating if interested in maintaining a healthy lifestyle!

If you’re taking this medication in its liquid form, be sure to measure out your dose carefully using a special measuring device/spoon. Please do not use household spoons because they may produce less effect than desired and risk giving yourself too much.

Your prescription dosage is based on what works best for you and your medical condition. Do not increase or change the frequency of doses without consulting with a doctor first.

Take this medication regularly to get the most benefit from it. To help you remember, take one in the morning and another at noon.

Side effects of Baclofen

Baclofen may cause serious side effects, including:

  • mood changes
  • confusion
  • depression
  • hallucinations

Get medical help right away if you have any of the symptoms listed above. The most common side effects of Baclofen include:

  • drowsiness
  • dizziness
  • weakness
  • tiredness
  • headache
  • trouble sleeping
  • nausea
  • increased urination
  • constipation

Precautions

You must not use or take this medication if you are allergic to it, and to ensure that it is safe to have it, you must first consult with your doctor. Tell your doctor if you’re suffering from these problems.

  • Mental illness or psychosis
  • Nervous system disorder
  • Kidney disease
  • Epilepsy or other seizure disorder
  • Stroke or blood clot

The risk of developing an ovarian cyst may increase when Baclofen is used; consult with your healthcare professionals to avoid any risk. You must not take Baclofen on two conditions:

During pregnancy– Your newborn baby could be experiencing withdrawal symptoms, such as tremors and rigid muscles. Watch for a drop in moodiness or irritability when you taper your dose before the due date approaches.

While breastfeeding– Some babies experience withdrawal symptoms when their mothers stop breastfeeding. Make sure you ask your doctor if it’s safe for you to breastfeed while taking this medicine, as some babies do have trouble adjusting after the end of suckling.

Taking Baclofen can be a tricky business, and if you don’t know how it affects your body, it could have disastrous consequences. For example: do not drive or operate heavy machinery until at least two weeks after taking this drug. Stopping the use of Baclofen suddenly could have some drastic withdrawal symptoms.

Dosages of Baclofen

Start therapy at a low dosage and increase gradually until optimum effect is achieved. It will usually take between 40-80 mg of tryptophan per day (in the form of supplement or food), but there may need to be additional increases if you’re having trouble finding your sweet spot for this amount.

The total daily dose should not exceed 80 milligrams, 20mg taken in single doses with breakfast & lunchtime meals; 5mg before bedtime.

If you miss a dose, take it as soon as possible and not later than 12 hours past the scheduled intake.

If your next planned time for taking medication approaches quickly (e.g., within 7-10 days), skip that missed one to avoid overlapping with an upcoming event/activity where double dosage would be too much of a hassle or even potentially dangerous.

Over dosages

Many types of research have been done on Baclofen, and it is reported that over dose may have symptoms that include:

  • General weakness
  • Vomiting
  • Respiratory insufficiency
  • Sedation
  • Unusual pupil size
  • Seizures
  • Dizziness
  • Itching
  • Hypothermia
  • Hypertension
  • Coma and death
  • Hyporeflexia
  • Headaches
  • Bradycardia  

Storage

Store this medication in a cool, dark place. Store both tablet and liquid forms of the drug separately from any other medications, so they don’t mix; the good idea is to put them inside an individual pillbox or bottle for easy disposal if needed.

You should also keep children away from these substances until you know how they interact with their body systems. Some people are more sensitive than others when exposed to too many potentially harmful things at once.

Baclofen withdrawal

People who have previously misused Baclofen reported that tolerance could develop easily.

Withdrawals symptoms are severe and potentially dangerous when not treated by medical professionals, which is why it’s important to seek help right away if you’re struggling with addiction or abuse of this medication.

Baclofen withdrawal symptoms include:

  • Increase in or return of spasticity
  • Itching
  • Low blood pressure
  • Lightheadedness
  • Tingling sensations

When untreated, early symptoms of withdrawal can progress to more severe and unpleasant ones. Advanced ones include high fever, changed mental status, or abnormal behavior in animals such as excessive fetching that could lead them away from home.

If it’s not treated soon enough, muscle stiffness may force a lion into hiding until it’s irritable before passing out stiff from hunger/dehydration because they don’t have food anymore; then finally death.

Interactions

Medication interactions are a complicated and sometimes explosive issue. This document does not contain all possible drug combinations, so be sure to check with your doctor before combining medications.

When you use some products, keep a list of them, including prescribed and non-prescribed drug and herbal products, and share it with your pharmacist and doctors.

If you’re taking other products that cause drowsiness, such as opioid pain or cough relievers (such as codeine), alcohol, marijuana, and drugs for sleep or anxiety-like alprazolam; cyclobenzaprine; cetirizine, then talk to your doctor.

Where can I Buy Baclofen?

Baclofen oral tablets are only available in its generic form. There is no brand-name version of the drug available. You can buy Baclofen online only using a doctor’s prescription. Any pharmacy willing to provide the drug without a prescription or under any illicit brand name is potentially a fraudulent pharmacy providing counterfeit medications.

Conclusion

Above, we have provided brief information about Baclofen and its history, so do check it. Always consult with your healthcare professional to ensure that the information provided on the page applies to your circumstances.

References

  1. Ghose, K., Holmes, K.M. and Matthewson, K., 1980. Complications of baclofen overdosage. Postgraduate medical journal56(662), pp.865-867. Available at: https://pmj.bmj.com/content/56/662/865.short Accessed on 10/09/2021
  2. Fromm, G.H., 1994. Baclofen as an adjuvant analgesic. Journal of pain and symptom management9(8), pp.500-509. Available at: https://www.sciencedirect.com/science/article/pii/0885392494901112 Accessed on 10/09/2021