Aspirin is a part of the nonsteroidal anti-inflammatory drug class. Aspirin was the first medicine of this type to be found. Aspirin contains salicylate, a chemical found in plants such as the willow tree and myrtle. It was used for the first time roughly 4,000 years ago. It reduces pain and swelling by blocking a particular natural chemical in your body.
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Purpose Of The Medication
- Aspirin can help with mild to severe discomfort, swelling, or both linked with a va riety of health problems, including headaches, the flu, sprains and strains, menstrual cramps, and long-term illnesses including arthritis and migraines.
- Systemic lupus erythematosus, Osteoarthritis, Rheumatoid arthritis, and other rheumatologic disorders are all treated with prescription aspirin.
- Aspirin also prevents heart attacks in persons who have already experienced a heart attack or who have angina pectoris (chest pain that occurs when the heart does not get enough oxygen).
- Nonprescription aspirin is also used to lower the risk of death in persons who have had a heart attack.
- Aspirin can also be taken alongside other medications such as antacids, pain relievers, and cough and cold medicines (Buring, J.E. 1993).
How To Consume Aspirin
Aspirin should be taken exactly as indicated on the label or as directed by your doctor. When giving aspirin to a child, always follow the guidelines on the drug package.
If aspirin makes your stomach uncomfortable, take it with food. Before swallowing the chewable tablet, you must chew it. An enteric-coated or delayed/extended-release pill should not be crushed, chewed, broken, or opened. Completely swallow the pill.
If you show signs of fever for more than three days, your discomfort lasts longer than ten days, or the painful area turns red or swollen, stop taking aspirin and see your doctor. You may have a medical problem that necessitates medical attention.
Forms & Strengths of Aspirin
Tablet : 81mg, 325mg, 500mg
Tablet, delayed-release: 162mg
Dosage
Normal Adult Dose for Osteoarthritis
Starting dose: 3 g orally per day in different doses
Maintenance: Manage dose as needed for anti-inflammatory efficacy
Normal Adult Dose for Rheumatoid Arthritis
Starting dose: 3 g orally per day in different doses
Maintenance: Manage dose as needed for anti-inflammatory efficacy
Normal Adult Dose for Systemic Lupus Erythematosus
Starting dose: 3 g orally per day in different doses
Maintenance: Manage dose as needed for anti-inflammatory efficacy
Normal Adult Dose for Fever
Oral: As needed, use 300 to 650 mg orally every 4 to 6 hours.
Maximum dose: 4 g in 24 hours
Normal Adult Dose for Pain
Oral: As needed, 300 to 650 mg orally every 4 to 6 hours
Maximum dose: 4 g in 24 hours
Side Effects Of Aspirin
- Swelling of the skin
- Bronchospasm
- Changes in the central nervous system (CNS)
- Problems with the skin
- Pain in the gastrointestinal tract (GI tract), ulceration, and bleeding
- Damage to the liver
- Hearing loss.
- Nausea
- Inhibition of platelet aggregation
- Hemolysis that occurs too soon
- Edema of the lungs (salicylate-induced, non-cardiogenic)
- Rash
- Damage to the kidneys
- The ears are ringing (tinnitus)
- Hives
- Vomiting
People who are pregnant or breastfeeding can use low-dose aspirin under the supervision of a doctor. High-dose aspirin is normally not recommended during pregnancy, according to doctors.
Anyone who has an allergy to aspirin or any other nonsteroidal anti-inflammatory medicine (NSAID), such as Ibuprofen, should avoid these medications. Since not all strokes are caused by blood clots, doctors do not prescribe aspirin during a stroke. Aspirin may worsen a stroke in some situations (Patrono, C. and Roth, G., 1995).
Storage
Keep this medication tightly closed and out of the reach of children in the container it came in. The medicine should be stored at room temperature, free from heat and moisture. Any tablets with a strong vinegar odor should be discarded.
Because many containers are not child-resistant and small children can readily open them, it is critical to keep all medicine containers out of sight and reach of children.
Is it Safe to give Aspirin to Children?
Aspirin is normally not recommended for people under the age of 18. This is because it raises the risk of Reye’s syndrome, a dangerous disorder that can develop after a viral infection such a cold, the flu, or chickenpox. Reye’s syndrome can result in death or irreversible brain damage. If a child needs to prevent blood clots after heart surgery, a doctor may prescribe aspirin under supervision.
Drug Interactions
Although some drugs should never be taken together, in other circumstances, two separate drugs can be used together even though interaction is possible. In certain circumstances, your doctor may wish to adjust the dose or take other precautions.
If you’re taking this medication, it’s especially vital to let your doctor know if you’re also taking any anti-inflammatory medications like diclofenac, ibuprofen, and naproxen. These medications, when used with aspirin, can increase the risk of gastrointestinal bleeding.
Mifepristone, acetazolamide, “blood thinners” such as warfarin, corticosteroids, dichlorphenamide, methotrexate, valproic acid, and herbal drugs are some of the items that may also interact with this drug.
