robaxin vs flexeril

The generic name for Robaxin is Methocarbamol, Cyclobenzaprine, being the generic name of Flexeril. Methocarbamol and Cyclobenzaprine are examples of skeletal muscle relaxants (SMRs) that your doctor might prescribe if you have muscle pain. Robaxin and Flexeril are both effective treatments for musculoskeletal pain and muscle spasms.

Robaxin vs. Flexeril are classified as antispasmodic agents and effective in treating acute painful musculoskeletal disorders that cause discomfort and muscle spasms.

What are the Differences between Flexeril and Robaxin?

main difference between flexeril and robaxin

• Flexeril was approved for medical use in the United States in 1977, Robaxin was approved by FDA on 16 July 1957.
• The precise mechanism of Flexeril is still not entirely determined. Still, the drug seems to initially act at the brain stem to lessen tonic somatic motor activity, affecting both gamma and alpha motor neurons, leading to decreased muscle spasms. The mechanism of Robaxin is still not been confirmed.
• The dosage form of Flexeril is tablet and capsule. Robaxin comes in the dosage form of a tablet and injectable solution.

Difference between their Side Effects

General side effects of Robaxin are-

  • Stomach upset
  • Nausea
  • Vomiting
  • Flushing
  • Constipation

General side effects of Flexeril-

  • Dry mouth or throat
  • Headache
  • Blurred vision
  • Drowsiness
  • Dizziness

Differences between their Warnings

• People experiencing thyroid disorder, heart block, congestive heart failure, a heart rhythm disorder, or have recently had a heart attack should not consume the medicine.
• Do not use the drug if you have taken an MAO inhibitor in the past 14 days.
• The drug is not approved for people younger than 15-year-old.
• Brief your doctor about your past and current medical conditions and medicines if you are consuming any.
• Older people may be more sensitive to the effects of this drug.

• Do not take the drug if you have an allergy to methocarbamol.
• The drug may impair your thinking. Be alert or avoid driving or activities that require mental alertness.
• Avoid taking alcohol when on this medication.
• The drug is not approved for people younger than 16-year-old unless to treat tetanus.

For Robaxin and Flexeril at a low-cost

Robaxin and Flexeril during Pregnancy and Breastfeeding?

Robaxin and flexeril during pregnancy and breastfeeding

• For Robaxin, there are no adequate studies that can determine the safety and effectiveness in pregnancy. Pregnant ladies should avoid muscle relaxers as it may cause harm to the unborn.
• Likewise, in breastfeeding, it is still not known whether the drug enters breast milk. The medicine should also be avoided in nursing mothers.
• No adequate studies of Flexeril in the pregnant woman. However, animals suggest no important effect on the fetus. Therefore, Flexeril can be used only when your health provider feels it is necessary.
• It is not known that Flexeril is secreted in milk. Caution is recommended in using this drug while breastfeeding.

Robaxin vs. Flexeril: who is more Effective?

Flexeril is the most studied drug and hence has more supporting proof of its effectiveness. According to the experiment done on patients, they felt slightly sounder improvements in local pain with Cyclobenzaprine (48% vs. 40%).

Methocarbamol is the best-known brand, while Roboxin is an effective muscle relaxant recommended as a pain reliever for short-term muscle pain and muscle spasms. Methocarbamol is helpful in the treatment of seizures and muscle spasms as a result of the ingestion of toxic substances in cats and dogs.


Robaxin is for short-term treatment as prescribed by your physician. Similarly, Flexeril is not used for more than 2-3 weeks. Both Flexeril and Robaxin are used as muscle relaxants. It depends on your condition and medical history, which will be more effective for you. Take guidance from your health provider; they will direct the best suitable drug for you after examining your condition.

Another option is to select a specific muscle relaxant (such as methocarbamol or other drugs of the same class) based on the quality of the drug and the condition of the patient. When considering skeletal muscle relaxants for use in the elderly, as an aid to treat chronic pain, or in patients with multiple comorbidities who receive polypharmaceutical therapy that includes opioids and skeletal muscle medications, the medication selection for each patient needs careful consideration of these factors.


Robaxin is a CNS depressant with sedative and musculoskeletal relaxant properties.

Methocarbamol is mistaken as a narcotic due to its side effects of drowsiness, but it isn’t a narcotic. It is a CNS depressant and muscle relaxant to treat pain.

Both Robaxin and Flexeril drugs are muscle relaxants utilized to manage skeletal muscle conditions such as injury or pain. They are used mutually with rest and physical therapy.

According to the list released, Robaxin is the best muscle relaxant.


  1. TOURAY, T. and SOLWAY, S., 2003. Muscle relaxants for nonspecific low back pain: a systematic review within the framework of the cochrane collaboration. Spine28(17), pp.1978-1992. Available at: Accessed on 14/09/2021
  2. Post, R.E. and Dickerson, L.M., 2010. Dizziness: a diagnostic approach. American family physician82(4), pp.361-368. Available at: Accessed on 14/09/2021

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